Journals / Journal of Experimental and Clinical Medicine / 2026 / Volume: 42 Issue: 2

The histological examination of vena saphena magna as a graft In coronary artery bypass surgery

Koray Ak(MARMARA UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, DEPARTMENT OF CARDIOVASCULAR SURGERY)0000-0003-2782-5275
Ahmet Midi(Altınbaş University, School of Medicine, Department of Pathology)0000-0002-6197-7654
Ahmet Tepecik(Marmara University, School of Medicine, Intern Dr.)0009-0007-6042-068X
Cemre Can Ulukaya(Marmara University, School of Medicine, Intern Dr.)0009-0004-6697-2053
Mehmet Emin Deligöz(Marmara University, School of Medicine, Intern Dr.)0009-0000-4364-914X
Sercan Topal(Marmara University, School of Medicine, Intern Dr.)0009-0006-4353-4610
Sinan Akbaş(Marmara University, School of Medicine, Department of Cardiovascular surgery)0000-0003-3727-0891
Pages
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Publication Date
2025-06-30
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This study highlights the importance of examining the histology of vena saphena magna grafts to ensure their suitability as a bypass conduit in CABG surgery.

📌 3 Key Takeaways

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Objective & Hypothesis:Coronary artery bypass surgery (CABG) is one of the most frequently performed surgical procedures worldwide, owing to the increasing incidence of coronary artery disease, which remains a leading cause of death globally.
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Key Findings & Data:Following CABG, the development of occlusion in vein grafts is one of the significant indicators of poor prognosis, resulting in an increased risk of recurrent ischemic events and repeat revascularization.
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Conclusion & Impact:This study highlights the importance of examining the histology of vena saphena magna grafts to ensure their suitability as a bypass conduit in CABG surgery.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Coronary artery bypass surgery · Vena saphena magna · Graft

Abstract

Coronary artery bypass surgery (CABG) is one of the most frequently performed surgical procedures worldwide, owing to the increasing incidence of coronary artery disease, which remains a leading cause of death globally. Following CABG, the development of occlusion in vein grafts is one of the significant indicators of poor prognosis, resulting in an increased risk of recurrent ischemic events and repeat revascularization. In the early and late postoperative periods, the use of healthy grafts with intact endothelium is critical to reduce mortality and morbidity rates. In this study, the histopathological findings of the vena saphena magna grafts in 12 patients who underwent CABG were evaluated to identify any preoperative degenerative changes in the grafts. The findings of the study showed that preoperative morphological degeneration was minimal in most grafts. However, in one sample, intimal fibrosis narrowed the lumen, while another sample exhibited mild medial sclerosis. In contrast, all other samples showed minimal or no degeneration. Consequently, assessing the histopathological condition of vessels before the operation is crucial to avoid using unsuitable grafts and to direct the surgeon to use different grafts if necessary. This study highlights the importance of examining the histology of vena saphena magna grafts to ensure their suitability as a bypass conduit in CABG surgery.

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Cite This Article

Ak, K., Midi, A., Tepecik, A., Ulukaya, C. C., Deligöz, M. E., Topal, S., Akbaş, S. (2025). The histological examination of vena saphena magna as a graft In coronary artery bypass surgery. Journal of Experimental and Clinical Medicine, Volume: 42 Issue: 2. https://ajindex.com/articles/1422583

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