Journals / Journal of Clinical and Experimental Investigations / 2026 / Cilt: 5 Sayı: 2

Comparison of the hemodynamic effects of etomidate between hypertensive and normotensive patients

Pages
164–168
Publication Date
2014-06-01
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J Clin Exp Invest 2014; 5 (2): 164-168

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Comparison of the hemodynamic effect of ethomidate induction in normotensive and hypertensive patients.
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Key Findings & Data:Methods: Forty ASA 1-2 patients were included.
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Conclusion & Impact:J Clin Exp Invest 2014; 5 (2): 164-168
🔬Design:Makale
📍Scope:2014 Verileri
⚙️Variables:Hemodinamik etki · etomidat · hipertansiyon

Abstract

Objective: Comparison of the hemodynamic effect of ethomidate induction in normotensive and hypertensive patients. Methods: Forty ASA 1-2 patients were included. After informed consent were obtained, patients were divided into two group; Group H: Hypertensive patients, Group N: Normotensive patients. Fentanile and midazolam were administrated for premedication. Anesthesia induction was performed by etomidate 0.3 mg/kg and rocuronium 0.6 mg/kg. Arterial pressures and heart rates were measured at certain intervals: control, pre-intubation and 1, 3 and 5 min post-intubation. Myoclonic movements and hemodynamic parameters were noted by an anesthetist who was masked to the groups. Results: Hemodynamic parameters were higher in hypertensive patients but were in clinically tolerable limits. Conclusion: No hemodynamic instability was observed in anesthesia induction with ethomidate in neither hypertensive nor normotensive patients. J Clin Exp Invest 2014; 5 (2): 164-168

Özet

Amaç: Etomidat ile anestezi indüksiyonunun hipertansif ve normotansif hastalarda hemodinamik etkilerini karşılaştırmayı amaçladık. Yöntemler: Etik komite onayı ve hastaların yazılı ve sözlü onamları alındıktan sonra genel anestezi altında çeşitli elektif cerrahi girişim uygulanacak olan 40 ardışık ASA I-II hasta çalışmaya alındı. Hastalar rastgele 2 gruba ayrıldı: Grup H (Hipertnasif hastalar), Grup N (Normotansif hastalar). Hastalar anestezi indüksiyonundan önce fentanil ve midazolam ile premedike edildi. Anestezi indüksiyonu etomidat 0.3 mg/kg ve rokuornyum 0.6 mg/kg ile yapıldı. Arteriyal basınçlar ve kalp hızı şu zamanlarda ölçüldü: kontrol, entübasyon öncesi ve entübasyondan 1, 3, 5 dakika sonra. Grup ayrımından habersiz bir anestezist tarafından miyoklonik hareketler ve hemodinamik parametreler kaydedildi. Bulgular: Hemodinamik parametreler tüm dönemlerde hipertansif hastalarda daha yüksekti fakat kabul edilebilir klinik sınırlar içindeydi. Sonuç: Ne hipertansif ne de normotansif hastalarda anestezi indüksiyonunda etomidatla hemodinamik instabilite yoktu.

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Cite This Article

Çiftçi, T., Daşkaya, H., Uzman, S., Gün, Y., Toptaş, M., İnal, F. Y., Demir, M. (2014). Comparison of the hemodynamic effects of etomidate between hypertensive and normotensive patients. Journal of Clinical and Experimental Investigations, Cilt: 5 Sayı: 2, 164–168. https://doi.org/10.5799/ahinjs.01.2014.02.0383

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