SavedAdd your journal

Journals / Journal of Clinical and Experimental Investigations / 2026 / Cilt: 6 Sayı: 1

-

Vernal keratokonjonktivitli olgularda ortalama trombosit hacmi ve nötrofil/lenfosit oranı

Bilal Elbey
Ümit Yazgan
Adnan Yıldırım
Ümit Karaalp
Alparslan Şahin
Pages
40–43
Publication Date
2015-05-10
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

J Clin Exp Invest 2015; 6 (1): 40-43

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: It was aimed to investigate the neutrophil, eosinophil, lymphocyte, platelet count, neutrophil to lymphocyte ratio (NLR) and mean platelet volume (MPV) in patients with vernal keratoconjunctivitis (VKC).Methods: The medical records of the VKC patients who admitted to ophthalmology polyclinic were evaluated.
📊
Key Findings & Data:Data were compared between the groups.Results: Thirty patients and 30 control subjects were studied.
💡
Conclusion & Impact:J Clin Exp Invest 2015; 6 (1): 40-43
🔬Design:Makale
📍Scope:2015 Verileri
⚙️Variables:Nötrofil lenfosit oranı · ortalama trombosit hacmi · vernal keratokonjonktivit

Abstract

Objective: It was aimed to investigate the neutrophil, eosinophil, lymphocyte, platelet count, neutrophil to lymphocyte ratio (NLR) and mean platelet volume (MPV) in patients with vernal keratoconjunctivitis (VKC).Methods: The medical records of the VKC patients who admitted to ophthalmology polyclinic were evaluated. Age and sex matched control group was consisted with patients without any systemic or ocular disease except strabismus. Age and gender of all participants were recorded. Hemogram parameters such as mean platelet volume (MPV), neutrophil, eosinophil, lymphocyte, platelet count, NLR were measured by automatized analyzer. Data were compared between the groups.Results: Thirty patients and 30 control subjects were studied. There were no significant differences with respect to age and gender between groups. The mean MPV and NLR values were higher but not statistically significant in VKC group compared to control group (p=0.19, p=0.16, respectively). Conclusion: The results of the current study demonstrated that MPV and NLR values were not associated with VKC. Higher MPV and NLR results in patients with VKC although the differences were not reach statistically significances may suggest that MPV and NLR may be auxiliary parameter. J Clin Exp Invest 2015; 6 (1): 40-43

Özet

Amaç: Bu çalışmada vernal keratokonjonktiviti (VKK) olan hastaların nötrofil, eozinofil, lenfosit, trombosit sayı- sı, nötrofil/lenfosit oranı (NLO), ortalama trombosit hacmi (MPV) değerlendirilmesi amaçlanmıştır. Yöntemler: Bu çalışmada göz hastalıkları polikliniğine başvurmuş ve VKK tanısı almış olguların dosya kayıtları retrospektif olarak incelendi. Şaşılık dışında herhangi bir sistemik ve oküler hastalığı bulunmayan yaş ve cinsiyet uyumlu olgular kontrol grubuna dahil edildi. Tüm katı- lımcıların yaş ve cinsiyet verileri kaydedildi. Hemogram değerlerinden; MPV nötrofil, eozinofil, lenfosit, trombosit sayımı, NLO otomatik analizörlerle ölçüldü. Elde edilen veriler iki grup arasında karşılaştırıldı. Bulgular: Çalışma kapsamında 30 VKK ve 30 kontrol olgusu değerlendirildi. Gruplar arasında yaş ve cinsiyet açısından anlamlı farklılık saptanmadı. MPV ve NLO, VKK grubunda kontrol grubuna oranla daha yüksek olmasına rağmen istatistiksel olarak anlamlı değildi (sırasıyla p=0,19 ve p=0,16). Sonuç: Bu çalışmanın sonucunda MPV ve NLO değerlerinin VKK hastalığıyla ilişkili olmadığını gösterilmiştir. MPV ve NLO değerlerinin VKK’da istatistiksel olarak anlamlı olmamalarına rağmen daha yüksek olması VKK için yardımcı parametre olarak kullanılabilir. Anahtar kelimeler: Nötrofil lenfosit oranı, ortalama trombosit hacmi, vernal keratokonjonktivit

🔖

Cite This Article

Elbey, B., Yazgan, Ü., Yıldırım, A., Karaalp, Ü., Şahin, A. (2015). -. Journal of Clinical and Experimental Investigations, Cilt: 6 Sayı: 1, 40–43. https://doi.org/10.5799/ahinjs.01.2015.01.0483

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (56)

  1. Kanski JJ. Clinical ophthalmology. A systematic approach
  2. nd ed Boston, Massachusetts: ButterworthHeinemann;629.
  3. El-Asrar A.A, Al-Mansouri S, Tabbara K, et al. Immunopathogenesis
  4. of conjunctival remodeling in vernal
  5. keratoconjunctivitis. Eye 2005;20:71-79.
  6. Bonini S, Bonini S, Lambiase A, et al. Vernal keratoconjunctivitis
  7. revisited: a case series of 195 patients with
  8. long-term follow up. Ophthalmology 2000;107:1157-
  9. Kosrirukvongs P, Vichyanond P, Wongsawad W. Vernal
  10. keratoconjunctivitis in Thailand. Asian Pac J Allergy
  11. Immunol 2003;21:25-30.
  12. Şahin A, Şahin M, Yüksel H, et al. The mean platelet
  13. volume in patients with retinal vein occlusion. J Ophthalmol;236371.
  14. Çil H, Yavuz C, İslamoğlu Y, et al. Platelet count and
  15. mean platelet volume in patients with in-hospital
  16. deep venous thrombosis. Clin Appl Thromb Hemost;18:650-653.
  17. Giles H, Smith R, Martin J. Platelet glycoprotein IIb-IIIa
  18. and size are increased in acute myocardial infarction.
  19. Eur J Clin Invest. 1994;24:69-72.
  20. Alkhouri N, Morris SG, Campbell C, et al. Neutrophil
  21. to lymphocyte ratio: a new marker for predicting steatohepatitis
  22. and fibrosis in patients with nonalcoholic
  23. fatty liver disease. Liver Int 2012;32:297-302.
  24. Cho SY, Lee A, Lee HJ, et al. Mean platelet volume
  25. in Korean patients with hepatic diseases. Platelets;23:648-649.
  26. Arikanoglu A, Yucel Y, Acar A, et al. The relationship of
  27. the mean platelet volume and C-reactive protein levels
  28. with mortality in ischemic stroke patients. Eur Rev
  29. Med Pharmacol Sci 2013;17:1774-1777.
  30. Celik T, Kaya M.G, Akpek M, et al, Predictive value
  31. of admission platelet volume indices for in-hospital
  32. major adverse cardiovascular events in acute STsegment
  33. elevation myocardial infarction. Angiology;66:155-162
  34. Ranjith M, Divya R, Mehta V, et al. Significance of
  35. platelet volume indices and platelet count in ischaemic
  36. heart disease. J Clin Pathol 2009;62:830-833.
  37. Hourani S, Cusack N. Pharmacological receptors on
  38. blood platelets. Pharmacol Rev 1991;43:243-298.
  39. Baudouin C, Liang H, Bremond G.D, et al. CCR4 and
  40. CCR5 expression in conjunctival specimens as differential
  41. markers of T H 1/T H 2 in ocular surface disorders. J Allergy Clin Immunol;116:614-619.
  42. Aragona P, Romeo G, Puzzolo D, et al. Impression
  43. cytology of the conjunctival epithelium in patients with
  44. vernal conjunctivitis. Eye 1996;10:82-85.
  45. Rifaioglu E, Şen B, Ekiz Ö, Dogramaci A. Neutrophil
  46. to lymphocyte ratio in Behcet’s disease as a marker of
  47. disease activity. Acta Dermatovenerol Alp Pannonica
  48. Adriat 2014;23:65-67.
  49. Akboğa MK, Akyel A, Şahinarslan A, et al. Neutrophil
  50. to lymphocyte ratio is increased in patients with rheumatic
  51. mitral valve disease. Anadolu Kardiyol Derg; [Epub ahead of print]
  52. Oray M, Toker E. Tear cytokine levels in vernal keratoconjunctivitis:
  53. the effect of topical 0.05% cyclosporine
  54. a therapy. Cornea 2013;32:1149-1154.
  55. Çatak O, Aydemir O, Üstündağ B. Vernal keratokonjonktivitte
  56. gözyaşı interlökin-16 düzeyleri. Dicle Med J;40:422-425.