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Journals / İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi / 2026 / Sayı: 25

The Prognostic Importance of Protein Energy Wasting in Chronic Kidney Disease: A Sectional Monocentric Study

Kronik Böbrek Hastalıklarında Protein Enerjisi İsrafının Prognostik Önemi: Kesitsel Tek Merkezli Bir Çalışma

Sümeyye Kemaneci(BURDUR MEHMET AKİF ERSOY ÜNİVERSİTESİ, SAĞLIK BİLİMLERİ FAKÜLTESİ)0000-0001-6974-8461
Alev Keser(ANKARA ÜNİVERSİTESİ)0000-0003-2620-6747
Pages
180–195
Publication Date
2025-04-29
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

So, using the PEW tool at certain intervals from the moment of diagnosis will be a practical and effective intervention in reducing the prevalence of malnutrition.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: The purpose of this study is to determine the frequency of Protein Energy Wasting (PEW) in individuals with chronic kidney disease (CKD) and evaluate the relationship between PEW and anthropometric measurements, biochemical parameters, and nutritional status of individuals.
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Key Findings & Data:Method: The study was conducted with 119 predialysis individuals aged 19 and over with CKD.
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Conclusion & Impact:So, using the PEW tool at certain intervals from the moment of diagnosis will be a practical and effective intervention in reducing the prevalence of malnutrition.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Antropometrik ölçümler · beslenme · kronik böbrek hastalığı

Abstract

Aim: The purpose of this study is to determine the frequency of Protein Energy Wasting (PEW) in individuals with chronic kidney disease (CKD) and evaluate the relationship between PEW and anthropometric measurements, biochemical parameters, and nutritional status of individuals. Method: The study was conducted with 119 predialysis individuals aged 19 and over with CKD. The biochemical parameters and anthropometric measurements of the participants were evaluated, and their nutritional status was determined by Subjective Global Assessment (SGA) and PEW criteria. Nutritional status was classified as good, moderate nutritional deficiency, and severe malnutrition according to SGA. The presence of PEW was accepted if ≥3 categories for PEW were met. Results: According to SGA, 20.2% of the individuals had moderate/severe malnutrition and 8.4% PEW. It was determined that with the increase in the number of PEW criteria in individuals, the body weight, body mass index (BMI), upper middle arm circumference, triceps skin fold thickness and body fat percentage; serum total protein, albumin, calcium and magnesium levels; intake amounts of many macro and micro nutrients have decreased significantly. It was detected that BMI (26.8%), albumin (18.6%), fiber (14.1%) and magnesium (15.7%) were the parameters most explaining the number of PEW criteria met by individuals. Conclusion: PEW was related to anthropometric measurements, biochemical parameters and nutrient intakes. So, using the PEW tool at certain intervals from the moment of diagnosis will be a practical and effective intervention in reducing the prevalence of malnutrition.

Özet

Amaç: Bu çalışmanın amacı kronik böbrek hastalığı (KBH) olan bireylerde Protein Enerji Kaybı (PEK) sıklığını belirlemek ve PEK ile bireylerin antropometrik ölçümleri, biyokimyasal parametreleri ve beslenme durumları arasındaki ilişkiyi değerlendirmektir. Yöntem: Çalışma 19 yaş ve üzeri KBH'li 119 diyaliz öncesi birey ile gerçekleştirildi. Katılımcıların biyokimyasal parametreleri ve antropometrik ölçümleri değerlendirilerek beslenme durumları Subjektif Global Değerlendirme (SGD) ve PEK kriteri ile belirlendi. Beslenme durumu SGA'ya göre iyi, orta derecede beslenme yetersizliği ve ciddi beslenme yetersizliği olarak sınıflandırıldı. PEK için ≥3 kategorinin karşılanması durumunda PEK'in varlığı kabul edildi. Bulgular: SGD'ye göre bireylerin %20,2'sinde orta/ciddi malnütrisyon, %8,4'ünde PEK vardı. Bireylerde PEK kriterlerinin sayısının artmasıyla birlikte vücut ağırlığı, beden kütle indeksi (BKİ), üst orta kol çevresi, triseps deri kıvrım kalınlığı ve vücut yağ yüzdesinin; serum toplam protein, albümin, kalsiyum ve magnezyum düzeyleri; birçok makro ve mikro besinin alım miktarları önemli ölçüde azalmıştır. Bireylerin karşıladığı PEK kriteri sayısını en çok açıklayan parametrelerin BKİ (%26,8), albümin (%18,6), posa (%14,1) ve magnezyum (%15,7) olduğu belirlendi. Sonuç: PEK antropometrik ölçümler, biyokimyasal parametreler ve besin alımıyla ilişkiliydi. Dolayısıyla tanı anından itibaren PEK aracının belirli aralıklarla kullanılması malnütrisyon prevalansının azaltılmasında pratik ve etkili bir müdahale olacaktır.

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Cite This Article

Kemaneci, S., Keser, A. (2025). The Prognostic Importance of Protein Energy Wasting in Chronic Kidney Disease: A Sectional Monocentric Study. İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi, Sayı: 25, 180–195. https://doi.org/10.38079/igusabder.1514884

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