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Journals / Acta Medica / 2020 / Cilt: 51 - Sayı: 2

Stroke-Like Hemiparesis During Acute Lymphoblastic Leukemia Treatment

İnci Yaman BAJİN
Barış KUŞKONMAZ
Şule ÜNAL
Mualla ÇETİN
Selin ARDALI
Kader KARLI OĞUZ
Fatma GÜMRÜK
Pages
43–48
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Clinical findings including headache, nausea, emesis, lethargy, altered mental status, blurred vision, aphasia, dysphasia, hemiparesis and cranial magnetic resonance imaging findings of restricted diffusion that does not comply with the territory of any artery should alert the physician for methotrexate-induced acute encephalopathy.

📌 3 Key Takeaways

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Objective & Hypothesis:In this case report; a 12-year-old male with acute lymphoblastic leukemia who developed transient left hemiparesis associated with dysphasia and central facial paralysis 14 days after high dose methotrexate (5g/m2 ) and intrathecal methotrexate (12 mg, according to age) treatment has been reported.
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Key Findings & Data:Cranial magnetic resonance imaging revealed restricted diffusion in bilateral centrum semiovale compatible with methotrexate-induced acute encephalopathy.
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Conclusion & Impact:Clinical findings including headache, nausea, emesis, lethargy, altered mental status, blurred vision, aphasia, dysphasia, hemiparesis and cranial magnetic resonance imaging findings of restricted diffusion that does not comply with the territory of any artery should alert the physician for methotrexate-induced acute encephalopathy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

In this case report; a 12-year-old male with acute lymphoblastic leukemia who developed transient left hemiparesis associated with dysphasia and central facial paralysis 14 days after high dose methotrexate (5g/m2 ) and intrathecal methotrexate (12 mg, according to age) treatment has been reported. Cranial magnetic resonance imaging revealed restricted diffusion in bilateral centrum semiovale compatible with methotrexate-induced acute encephalopathy. All clinical symptoms resolved completely without any treatment. Clinical findings including headache, nausea, emesis, lethargy, altered mental status, blurred vision, aphasia, dysphasia, hemiparesis and cranial magnetic resonance imaging findings of restricted diffusion that does not comply with the territory of any artery should alert the physician for methotrexate-induced acute encephalopathy.

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Cite This Article

BAJİN, İ. Y., KUŞKONMAZ, B., ÜNAL, Ş., ÇETİN, M., ARDALI, S., OĞUZ, K. K., GÜMRÜK, F. (2020). Stroke-Like Hemiparesis During Acute Lymphoblastic Leukemia Treatment. Acta Medica, Cilt: 51 - Sayı: 2, 43–48. https://ajindex.com/articles/141618

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