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Journals / International Journal of Pure and Applied Sciences / 2024 / Volume: 10 Issue: 2

Investigation the Biological Activities of Chenopdium foliosum Methanol Extract

Özge Vazgeçen(İNÖNÜ ÜNİVERSİTESİ)0009-0000-7260-4442
Irmak Icen Taskın(INONU UNIVERSITY)0000-0002-1612-0563
Meryem Rüveyda Sever(İNÖNÜ ÜNİVERSİTESİ)0000-0001-9271-1528
Pelin Yılmaz Sancar(FIRAT ÜNİVERSİTESİ)0000-0002-6134-622X
Pages
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Publication Date
2024-12-31
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Elde edilen bulgular C. folisoum metanol ekstraktının HCT116, A549 ve C. albicans'a karşı hem antikanser hem de antifungal etkiye sahip olduğunu göstermektedir.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Chenopodium cinsi Türkiye dahil hemen hemen dünyanın her yerinde yayılış göstermektedir.
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Key Findings & Data:Bu cinse ait türler farklı ülkelerin geleneksel tıbbında çeşitli hastalıkların tedavisinde kullanılmaktadır.
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Conclusion & Impact:Elde edilen bulgular C. folisoum metanol ekstraktının HCT116, A549 ve C. albicans'a karşı hem antikanser hem de antifungal etkiye sahip olduğunu göstermektedir.
🔬Design:Lab & Field Experiment
📍Scope:Comprehensive Sample
⚙️Variables:Chenopodium · anti-cancer · anti-bacterial

Abstract

Chenopodium cinsi Türkiye dahil hemen hemen dünyanın her yerinde yayılış göstermektedir. Bu cinse ait türler farklı ülkelerin geleneksel tıbbında çeşitli hastalıkların tedavisinde kullanılmaktadır. Chenopodium cinsinin farklı türleri anti-kanser, anti-mantar ve anti-bakteriyel etkiler göstermektedir. Chenopo-dium foliosum (C. folisoum) ile ilgili literatürde büyük bir boşluk bulunmak-tadır. Bu çalışmada C. folisoum bitkisinin metanol ekstraktının biyolojik ak-tiviteleri araştırıldı. Anti-kanser aktivitesi, HCT-116 ve A549 hücre hatlarında 3-(4,5-Dimetiltiazol-2-il)-2,5-difeniltetrazolyum bromür (MTT) analizi kullanılarak değerlendirildi. Anti-bakteriyel ve ati-fungal aktivitesi minimum inhibisyon konsantrasyonu (MIC) tahlili ile incelenmiştir. C. folisoum'un metanol ekstraktı, HCT116 ve A549 hücre hatlarının hücre canlılığını sırasıyla %73,4 ± %15,3 ve %78,7 ± %2,3'e düşürdüğü saptanmıştır. C. folisoum ayrıca candida albicans'ın (C. albicans) hücre canlılığını %91,2'ye düşürdüğü saptanmıştır. Elde edilen bulgular C. folisoum metanol ekstraktının HCT116, A549 ve C. albicans'a karşı hem antikanser hem de antifungal etkiye sahip olduğunu göstermektedir.

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Cite This Article

Vazgeçen, Ö., Taskın, I. I., Sever, M. R., Sancar, P. Y. (2024). Investigation the Biological Activities of Chenopdium foliosum Methanol Extract. International Journal of Pure and Applied Sciences, Volume: 10 Issue: 2. https://doi.org/10.29132/ijpas.1433939

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