Journals / Harran Üniversitesi Veteriner Fakültesi Dergisi / 2025 / Volume: 14 Issue: 2

Mineral and Heavy Metal Contents of Traditional Cheeses Produced in Southeastern Anatolia, Türkiye

Güneydoğu Anadolu’da Üretilen Geleneksel Peynirlerin Mineral ve Ağır Metal İçerikleri, Türkiye

Semra Gürbüz(MARDİN ARTUKLU ÜNİVERSİTESİ)0000-0002-7099-0308
Aslı Çelikel(MARDIN ARTUKLU UNIVERSITY)0000-0003-0583-295X
Pages
—
Publication Date
2025-12-24
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These findings underscore the importance of regularly monitoring heavy metals, including Pb, Cd, and As, in traditional cheeses to ensure food safety and protect public health.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:This study aimed to determine the mineral and heavy metal contents of traditional cheeses from the Southeastern Anatolia region of Türkiye, and to assess inter-provincial differences as well as potential public health risks.
📊
Key Findings & Data:A total of 30 cheese samples were analyzed for 15 minerals using the Inductively Coupled Plasma–Mass Spectrometry (ICP-MS), including Mardin Melted Cheese (Mardin), Şırnak Herbed Cheese (Şırnak), Batman Koçer Cheese (Batman), Diyarbakır Braided Cheese (Diyarbakır), and Urfa/Şanlıurfa Cheese (Şanlıurfa).
💡
Conclusion & Impact:These findings underscore the importance of regularly monitoring heavy metals, including Pb, Cd, and As, in traditional cheeses to ensure food safety and protect public health.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:ICP-MS · Traditional cheeses · Mineral

Abstract

This study aimed to determine the mineral and heavy metal contents of traditional cheeses from the Southeastern Anatolia region of Türkiye, and to assess inter-provincial differences as well as potential public health risks. A total of 30 cheese samples were analyzed for 15 minerals using the Inductively Coupled Plasma–Mass Spectrometry (ICP-MS), including Mardin Melted Cheese (Mardin), Şırnak Herbed Cheese (Şırnak), Batman Koçer Cheese (Batman), Diyarbakır Braided Cheese (Diyarbakır), and Urfa/Şanlıurfa Cheese (Şanlıurfa). Intergroup differences were evaluated using ANOVA and Kruskal–Wallis tests, relationships between minerals were assessed with correlation analysis, and geographical origins were examined using Principal Component Analysis (PCA). Mean mineral concentrations, from highest to lowest, were Na > Ca > K > Mg > Zn > Fe > Al > Pb > Cu > Cd > Mn > Cr > Ni > Se > As. Correlation analysis indicated strong positive associations between certain minerals, such as Pb and Cd, and notable negative associations, such as Zn and Ni, suggesting some elements co-occur while others vary inversely due to shared environmental or production-related factors. Principal Component Analysis identified six components explaining 80.80% of variance, showing province-specific patterns: higher Pb and Cd in Şırnak, elevated Ni, Mg, and Mn in Şanlıurfa, increased Ca and Zn in Diyarbakır and Batman, and an intermediate composition in Mardin. These findings underscore the importance of regularly monitoring heavy metals, including Pb, Cd, and As, in traditional cheeses to ensure food safety and protect public health.

Özet

Bu çalışma, Türkiye’nin Güneydoğu Anadolu bölgesindeki Mardin, Batman, Şırnak, Diyarbakır ve Şanlıurfa illerinde üretilen geleneksel peynirlerde mineral ve ağır metal düzeylerinin belirlenerek iller arası farklılıkların ve olası halk sağlığı risklerinin değerlendirmesi amaçlanmıştır. Toplam 30 peynir örneği, İndüktif Eşleşmiş Plazma–Kütle Spektrometresi – ICP-MS yöntemi ile 15 mineral açısından analiz edilmiştir. Mineral maddelerin konsantrasyonlarındaki gruplar arası farklar ANOVA ve Kruskal–Wallis testleri ile, mineral maddeler arasındaki ilişkiler korelasyon analizi ile ve peynirlerin coğrafi orijinleri Başlıca Bileşen Analizi (PCA) ile değerlendirilmiştir. Analizi yapılan minerallerin ortalama konsantrasyonları büyükten küçüğe Ca > Na > K > Mg > Zn > Fe > Al > Pb > Cu > Cd > Mn > Cr > Ni > Se olarak belirlenmiş olup, Mg, K ve Ca Mardin peynirlerinde oldukça yüksek konsantrasyonlarda bulunmuştur. Peynirlerde Pb, Cd ve As gibi ağır metallerin düzenli olarak izlenmesinin gıda güvenliğinin sağlanması açısından önemli olduğu değerlendirilmiştir.

🔖

Cite This Article

Gürbüz, S., Çelikel, A. (2025). Mineral and Heavy Metal Contents of Traditional Cheeses Produced in Southeastern Anatolia, Türkiye. Harran Üniversitesi Veteriner Fakültesi Dergisi, Volume: 14 Issue: 2. https://doi.org/10.31196/huvfd.1820603

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (41)

  1. Aday S, Karagul Yuceer Y, 2014: Physicochemical and sensory properties of Mihalic cheese. Int J Food Prop, 17 (10), 2207–2227. https://doi.org/https://doi.org/10.1080/10942912.2013.790904
  2. Aggarwal A, Parmar A, Panigrahi SP, Verma T, Dhyani P, Bajya SL, Singh MS, 2024: Exploring the probiotic and prebiotic dynamics of cheese: An updated review. Ann Phytomed, 13 (1), 360–369. http://dx.doi.org/10.54085/ap.2024.13.1.36
  3. Ali AAH, 2023: Overview of the vital roles of macro minerals in the human body. J Trace Elem Minerals, 4: 100076.
  4. Altınsoy C, Taban G, Tajdar-Oranj B, Sadighara P, Basaran B, 2025: Occurrence of potentially toxic metals in Turkish cheese with dietary intake and health risk assessment. Scientific Reports, 15 (1), 33416. https://doi.org/https://doi.org/10.1038/s41598-025-18813-1
  5. Balali-Mood M, Naseri K, Tahergorabi Z, Khazdair MR, Sadeghi M, 2021: Toxic mechanisms of five heavy metals: Mercury, lead, chromium, cadmium, and arsenic. Front Pharmacol, 12, 643972. doi: 10.3389/fphar.2021.643972
  6. Bansal V, Veena N, 2024: Understanding the role of pH in cheese manufacturing: General aspects of cheese quality and safety. J Food Sci Technol, 61 (1), 16–26. https://doi.org/https://doi.org/10.1007/s13197-022-05631-w
  7. Capcarova M, Frigenti M, Arvay J, Janco I, Harangozo L, Bandlerova A, Sartoni M, Guidi A, Stawarz R, Formicki G, 2024: Levels of essential and trace elements in mozzarella available on the Slovak market with the estimation of consumer exposure. Biol Trace Elem Res, 202 (5), 2357–2366. https://doi.org/https://doi.org/10.1007/s12011-023-03813-x
  8. Cesare Marincola F, Palmas C, Lastres Couto MA, Paz I, Cremades J, Pintado J, Bruni L, Picone G, 2025: Metabolic Profile of Senegalese Sole (Solea senegalensis) Muscle: Effect of Fish–Macroalgae IMTA-RAS Aquaculture. Molecules, 30, 2518.
  9. Codex Alimentarius Commission, 2024: FAO/WHO—Codex Alimentarius Commission. General Standard for Contaminants and Toxins in Food and Feed (CXS 193-1995); Updated 2023; FAO: Rome, Italy, (Available online: https://www.fao.org/fao-who-codexalimentarius/sh-proxy/en/? lnk=1&url=https%253A%252F%252Fworkspace.fao.org%252Fsites%252Fcodex%252FStandards%252FCXS%2B193-1995%252FCXS_193e.pdf (Accessed date: 27.11.2025).
  10. Elafify M, El-toukhy M, Sallam K, Sadoma N, Abd-Elghany S, Abdelkhalek A, El-Baz A, 2023: Heavy metal residues in milk and some dairy products with insight into their health risk assessment and the role of Lactobacillus rhamnosus in reducing the lead and cadmium load in cheese. Food Chem Adv, 2, 100261.
  11. Erol S, Ürkek B, 2025: Safety and nutritional profile of traditional Turkish cheeses: A comprehensive study on their mineral content, heavy metal contamination, and health risks of Aho, Golot, and Telli. Food Sci Nutr, 13 (7), e70560. https://doi.org/https://doi.org/10.1002/fsn3.70560
  12. European Commission, 2023: Regulation (EU) 2023/915 of 25 April 2023 on Maximum Levels of Certain Contaminants in Foodstuffs; Official Journal of the European Union, L119, 5 May 2023; Publications Office of the European Union: Brussels, Belgium, pp. 103–157.
  13. Farag MA, Abib B, Qin Z, Ze X, Ali SE, 2023: Dietary macrominerals: Updated review of their role and orchestration in human nutrition throughout the life cycle with sex differences. Curr Res Food Sci, 6, 100450. https://doi.org/10.1016/j.crfs.2023.100450
  14. Fox PF, Guinee TP, Cogan TM, McSweeney PLH, 2017: Cheese: Historical aspects. In Fundamentals of cheese science (pp. 1–10). Springer.
  15. Górska-Warsewicz H, Rejman K, Laskowski W, Czeczotko M, 2019: Milk and dairy products and their nutritional contribution to the average polish diet. Nutrients, 11 (8), 1771. https://doi.org/10.3390/nu11081771
  16. Gürbüz S, Çelikel Güngör A, 2020: Uludere Otlu Gömme Peynirinin Kimyasal ve Mikrobiyolojik Özellikleri, 4. Uluslararası Hipokrat Tıp ve Sağlık Bilimleri Kongresi 25-26 Eylül 2020, Antalya, Türkiye, ss. 163-168
  17. İșleyici Ö, Sancak YC, Tuncay RM, Yücel UM, 2017: Determination of mineral substance and heavy metal levels in Divle tulum cheese. Van Vet J, 28(3), 151–156.
  18. Kamber U, 2015: Traditional Turkey cheeses and their classification. Van Vet J, 26 (3), 161–171.
  19. Kılıç Altun S, Aydemir ME, 2021: Determination of some minerals and heavy metal levels in Urfa cheese and cow’s milk. Food and Health, 7 (3), 185–193. https://doi.org/https://doi.org/10.3153/FH21020
  20. Korenovská M, Suhaj M, 2008: Chemometric study of the contents of minerals and risk elements in some European hard cheeses. J Food Nutr Res, 47 (2).
  21. Köse Ş, Ceylan M, Altun İ, Erim Köse Y, 2022: Determınatıon of some basıc propertıes of tradıtıonal malatya cheese. Food Sci Technol, 42, e03921. https://doi.org/https://doi.org/10.1590/fst.03921
  22. Maione C, Barbosa F, Melgaço Barbosa R, 2019: Predicting the botanical and geographical origin of honey with multivariate data analysis and machine learning techniques: A review. Comput Electron Agric. 157, 436–446.
  23. Manuelian CL, Currò S, Penasa M, Cassandro M, De Marchi M, 2017: Characterization of major and trace minerals, fatty acid composition, and cholesterol content of Protected Designation of Origin cheeses. J Dairy Sci, 100 (5), 3384–3395. https://doi.org/https://doi.org/10.3168/jds.2016-12059
  24. Mehri A, 2020: Trace elements in human nutrition (II)–an update. Int J Prev Med, 11 (1), 2. Doi: 10.4103/ijpvm.IJPVM_48_19.
  25. Mendil D, 2006: Mineral and trace metal levels in some cheese collected from Turkey. Food Chem, 96(4), 532–537. https://doi.org/doi:10.1016/j.foodchem.2005.03.006
  26. Muneam R, Abojassim AA, 2023: Assessment of health risks for heavy metals in Iraqi, Iranian and Turkish of cheese samples available of Iraqi markets. Jordan J Phys, 16 (4), 491–500. Doi:https://doi.org/10.47011/16.4.12
  27. Necula D, Ungureanu-Iuga M, Dan SD, Tamas-Krumpe O, Ogean L, 2023: Analysis of the mineral profile of milk and swiss cheese from tara dornelor in relation to seasonal and technological factors. Stud Univ Babes-Bolyai Chem, 68 (3), 35–49. Doi:10.24193/subbchem.2023.3.03
  28. Ozlu H, Urcar S, Atasever M, 2012: Erzurum’da tüketime sunulan kaşar peynirlerinin mineral madde içeriği ve ağır metal kontaminasyonu. Kafkas Üniv Vet Fak Derg, 18 (2), 205–208.
  29. Paksoy N, Dinç H, Altun,SK, 2018: Evaluation of levels of essential elements and heavy metals in milks of dairy donkeys, goats and sheep in Turkey. Pak J Zool, 50(3).
  30. Razzaque MS, Wimalawansa SJ, 2025: Minerals and human health: from deficiency to toxicity. Nutrients, 17 (3), 454. https://doi.org/https://doi.org/10.3390/nu17030454
  31. Rizzoli R, Biver E, 2024: Role of fermented dairy products in the health benefits of a mediterranean diet. Aging Clin Exp Res, 36 (1):75. Doi: 10.1007/s40520-024-02721-x.
  32. Singh M, Ranvir S, Rajan Sharma RS, Gandhi K, Mann B, 2019: Assessment of contamination of milk and milk products with heavy metals. Indian J Dairy Sci, 72 (6), 608–615.
  33. Souto MRS, Pimenta AM, Catarino RIL, Leal MFC. Simões ETR, 2025: Heavy Metals in Milk and Dairy Products: Safety and Analysis. Pollutants, 5(3), 29. https://doi.org/10.3390/pollutants5030029
  34. Sukmana H, Rizwana I, Dobozi R, Al-Tayawi AN, Szabó BP, Özer B, Kertész S, 2025: A review of various protein separation techniques and valorization of cheese whey and buttermilk. Eur Food Res Technol, 1–17. https://doi.org/https://doi.org/10.1007/s00217-025-04877-w
  35. TOB, 2025a: Tarım ve Orman Bakanlığı, https://gelenekselpeynirler.tarimorman.gov.tr/Peynir/Detay/1053 (Accessed date: 20.11.2025).
  36. TOB, 2025b: Tarım ve Orman Bakanlığı, https://gelenekselpeynirler.tarimorman.gov.tr/Peynir/Detay/1157 (Accessed date: 20.11.2025).
  37. TOB, 2025c: Tarım ve Orman Bakanlığı, https://gelenekselpeynirler.tarimorman.gov.tr/Peynir/Detay/1051 (Accessed date: 20.11.2025).
  38. TPMK, 2013: Türk Patent ve Marka Kurumu, https://ci.turkpatent.gov.tr/cografi-isaretler/detay/38018 (Accessed date: 19.11.2025).
  39. TPMK, 2021: Türk Patent ve Marka Kurumu, https://ci.turkpatent.gov.tr/cografi-isaretler/detay/38631 (Accessed date: 19.11.2025).
  40. Turkish Food Codex. (2023). Turkish Food Codex Contaminants Regulation. Official gazette date: 05.11.2023, Number: 32360.
  41. Mehri A, 2020: Trace elements in human nutrition (II)–an update. Int J Prev Med, 11 (1), 2. Doi: 10.4103/ijpvm.IJPVM_48_19.