Journals / Harran Üniversitesi Veteriner Fakültesi Dergisi / 2026 / Volume: 15 Issue: 3

Evaluation of Ovarian and Uterine Pathological Lesions in Dogs Undergoing Ovariohysterectomy

Ovariohisterektomi Geçiren Köpeklerde Ovaryum ve Uterustaki Patolojik Lezyonların Değerlendirilmesi

Yavuz Musabeşeoğlu(BURDUR MEHMET AKİF ERSOY ÜNİVERSİTESİ, VETERİNER FAKÜLTESİ)0000-0001-6152-7787
Onur Çelikoğlu(BURDUR MEHMET AKİF ERSOY ÜNİVERSİTESİ)0000-0003-2743-7424
İbrahim Taşal(BURDUR MEHMET AKİF ERSOY UNIVERSITY)0000-0003-4632-3115
Zafer Özyıldız(BURDUR MEHMET AKİF ERSOY UNIVERSITY)0000-0002-6009-9191
Muhammed Albayrak(BURDUR MEHMET AKİF ERSOY ÜNİVERSİTESİ)0009-0006-1758-1042
Pages
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Publication Date
2026-09-23
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

These findings indicate that reproductive pathological lesions, including clinically unapparent lesions, may be present at a considerable rate in ovariohysterectomy materials.

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Objective & Hypothesis:This study aimed to evaluate the types, frequency, and distribution of pathological lesions observed in the ovarian and uterine tissues of female dogs subjected to ovariohysterectomy at the Department of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Burdur Mehmet Akif Ersoy University.
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Key Findings & Data:A total of 67 ovarian and uterine tissue samples obtained from bitches of different breeds and ages were examined.
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Conclusion & Impact:These findings indicate that reproductive pathological lesions, including clinically unapparent lesions, may be present at a considerable rate in ovariohysterectomy materials.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Dog · histopathology · ovarian pathology

Abstract

This study aimed to evaluate the types, frequency, and distribution of pathological lesions observed in the ovarian and uterine tissues of female dogs subjected to ovariohysterectomy at the Department of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Burdur Mehmet Akif Ersoy University. A total of 67 ovarian and uterine tissue samples obtained from bitches of different breeds and ages were examined. The samples were fixed in 10% formaldehyde, routinely processed, embedded in paraffin blocks, sectioned at 4-5 µm, and stained with Hematoxylin and Eosin for histopathological examination under a light microscope. Pathological lesions were detected in 23.88% of ovarian tissues. The most common ovarian lesions were follicular cysts (n=5; 7.46%) and luteal cysts (n=4; 5.97%), followed by paraovarian cysts (n=3; 4.48%) and polycystic ovaries (n=2; 2.98%). Oophoritis and ovarian remnant syndrome were each identified at a rate of (n=1;1.49%). In uterine tissues, pyometra was detected at a rate of (n=6; 8.95%), while pyometra associated with cystic endometrial hyperplasia was identified at a rate of (n=8; 11.94%). Metritis and serosal cysts were observed at a rate of (n=1; 1.49%). These findings indicate that reproductive pathological lesions, including clinically unapparent lesions, may be present at a considerable rate in ovariohysterectomy materials. Histopathological examination plays a crucial role in detecting clinically unapparent lesions and contributes significantly to the evaluation of reproductive health.

Özet

Bu çalışmanın amacı, XXXXX Üniversitesi Veteriner Fakültesi XXXXX Anabilim Dalı’nda rutin ovariohisterektomi uygulanan dişi köpeklerden elde edilen ovaryum ve uterus dokularında gözlenen patolojik lezyonların türlerini, sıklıklarını ve dağılımlarını değerlendirmektir. Farklı ırk ve yaşlardaki toplam 67 dişi köpeğe ait ovaryum ve uterus doku örneği incelendi. Doku örnekleri %10’luk formaldehit solüsyonunda tespit edildi, rutin histolojik işlemlerden geçirilerek parafin bloklara gömüldü, 4–5 µm kalınlığında kesitler alındı ve ışık mikroskobunda histopatolojik inceleme amacıyla Hematoksilen ve Eozin ile boyandı. Ovaryum dokularının %23,88’inde patolojik lezyonlar saptandı. En yaygın ovaryal lezyonlar foliküler kist (%7,46) ve luteal kist (%5,97) olup, bunları paraovaryan kist (%4,48) ve polikistik over (%2,98) izledi. Ooforitis ve ovaryum kalıntı sendromu ise ayrı ayrı %1,49 oranında belirlendi. Uterus dokularında piyometra %8,95 oranında saptanırken, kistik endometriyal hiperplazi ile birlikte görülen piyometra %11,94 oranında belirlendi. Metritis ve serozal kistler ise %1,49 oranında gözlendi. Bu bulgular, rutin ovariohisterektomi materyallerinde subklinik reprodüktif patolojilerin dikkate değer bir oranda bulunduğunu göstermektedir. Histopatolojik inceleme, klinik olarak belirti vermeyen lezyonların saptanmasında kritik bir rol oynamakta ve reprodüktif sağlığın değerlendirilmesine önemli katkı sağlamaktadır.

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Cite This Article

Musabeşeoğlu, Y., Çelikoğlu, O., Taşal, İ., Özyıldız, Z., Albayrak, M. (2026). Evaluation of Ovarian and Uterine Pathological Lesions in Dogs Undergoing Ovariohysterectomy. Harran Üniversitesi Veteriner Fakültesi Dergisi, Volume: 15 Issue: 3. https://doi.org/10.31196/huvfd.1939693

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References (22)

  1. Arlt, SP., Haimerl, P. (2016). Cystic ovaries and ovarian neoplasia in the female dog: A systematic review. Reproduction in Domestic Animals, 51, 3-11. https:// doi.org/10.1111/rda.12781
  2. Ball, RL., Birchard, SJ., May, LR., Threlfall, WR., Young, GS. (2010). Ovarian remnant syndrome in dogs and cats: 21 cases (2000-2007). Journal of the American Veterinary Medical Association, 236(5), 548-553.
  3. Bilen, EK., Karadağ, MA., Akgül, G., Gülendağ, E. (2025). Comparison of acute phase and haemostatic responses following ovariohysterectomy via midline or flank approach in dogs. Pakistan Veterinary Journal, 45(2), 866-872. DOI: 10.29261/ pakvetj/2025.152
  4. Costa, AS., Silva, MEM., dos Santos, TR., Bisinoto, MB., Tsuruta, SA., Borges, EBA., Saut, JPE. (2019). A retrospective study of reproductive disorders in female dogs from the city of Uberlândia, Minas Gerais, Brazil. Semina: Ciências Agrárias, 40(5, Suppl. 1), 2299-2308. DOI: 10.5433/1679-0359.2019v40n5Supl1p2299
  5. Domrazek, K., Kondratek, K., Tobolewski, F., Jurka, P. (2025). Prevalence, diagnosis, and treatment of ovarian cysts in bitches and queens: A meta-analysis. Animals, 15(19), 2800. https://doi.org/10.3390/ ani15192800
  6. Hanim, MS., Chotimanukul, S. (2025). Age-related canine reproductive health: Impact on fertility and disorders. Journal of Veterinary Science, 26(Suppl. 1), S139. doi: 10.4142/jvs.25218
  7. Jitpean, S., Hagman, R., Ström Holst, B., Höglund, OV., Pettersson, A., Egenvall, A. (2012). Breed variations in the incidence of pyometra and mammary tumours in Swedish dogs. Reproduction in Domestic Animals, 47, 347-350. https://doi.org/10.1111/rda.12103
  8. Kim, H., Choi, H., Kim, H., Choi, J. (2012). A giant parovarian cyst in a dog with a granulosa cell tumor. Journal of Veterinary Medical Science, 74(3), 385-389. https:// doi.org/10.1292/jvms.11-0414
  9. Knauf, Y., Köhler, K., Knauf, S., Wehrend, A. (2018). Histological classification of canine ovarian cyst types with reference to medical history. Journal of Veterinary Science, 19(6), 725-734. https://doi. org/10.4142/jvs.2018.19.6.725
  10. Lection, J., Cornelius, AJ., Moxon, R., Russenberger, J., de Amorim, MD., Cheong, SH. (2021). Incidence and risk factors for canine mastitis and metritis in two guide dog populations. Animal Reproduction Science, 231, 106802. https://doi.org/10.1016/j. anireprosci.2021.106802
  11. Maya-Pulgarin, D., Gonzalez-Dominguez, MS., Aranzazu- Taborda, D., Mendoza, N., Maldonado-Estrada, JG. (2017). Histopathologic findings in uteri and ovaries collected from clinically healthy dogs at elective ovariohysterectomy: A cross-sectional study. Journal of Veterinary Science, 18(3), 407-414. https://doi.org/10.4142/jvs.2017.18.3.407
  12. McRae, GR., Coutinho da Silva, MA., Runcan, EE., Stephens, JA., Premanandan, C. (2025). Histological studies in the endometrium of fertile and subfertile bitches. Reproduction in Domestic Animals, 60(4), e70055. https://doi.org/10.1111/rda.70055
  13. Nebel-Karp, A., Mahoney, D., Whitacre, M., Bauer, B., Lyle, S. (2025). Infertility caused by oophoritis in a dog resolved by hemiovariectomy. Clinical Theriogenology, 17. https://doi.org/10.58292/ CT.v17.10638
  14. Praderio, RG., Mitacek, MG., Favre, RN., Rearte, R., de la Sota, RL., Stornelli, MA. (2019). Uterine endometrial cytology, biopsy, bacteriology, and serum C-reactive protein in clinically healthy diestrus bitches. Theriogenology, 131, 153-161. https://doi. org/10.1016/j.theriogenology.2019.03.039
  15. Romagnoli, S., Krekeler, N., De Cramer, K., Kutzler, M., McCarthy, R., Schaefer-Somi, S. (2024). WSAVA guidelines for the control of reproduction in dogs and cats. Journal of Small Animal Practice, 65(7), 424-559.
  16. Roos-Pichenot, J., Zakošek Pipan, M. (2025). “My bitch is empty!” An overview of the preconceptional causes of infertility in dogs. Veterinary Sciences, 12(7), 663. https://doi.org/10.3390/vetsci12070663
  17. Sasidharan, JK., Patra, MK., Singh, LK., Saxena, AC., De, UK., Singh, V.,.Krishnaswamy, N. (2021). Ovarian cysts in the bitch: An update. Topics in Companion Animal Medicine, 43, 100511. https://doi.org/10.1016/j. tcam.2021.100511
  18. Tarafder, M., Samad, MA. (2010). Prevalence of clinical diseases of pet dogs and risk perception of zoonotic infection by dog owners in Bangladesh. Bangladesh Journal of Veterinary Medicine, 8(2), 163-174.
  19. Woźna-Wysocka, M., Rybska, M., Błaszak, B., Jaśkowski, BM., Kulus, M., Jaśkowski, JM. (2021). Morphological changes in bitches endometrium affected by cystic endometrial hyperplasia-pyometra complex: the value of histopathological examination. BMC Veterinary Research; 17, 174.
  20. Xavier, RGC., Santana, CH., de Castro, YG., de Souza, TGV., do Amarante, VS., Santos, RL., Silva, ROS. (2023). Canine pyometra: A short review of current advances. Animals, 13(21), 3310. https://doi. org/10.3390/ani13213310
  21. Zambelli, D., Ballotta, G., Guerra, D., Cunto, M. (2025). Ovarian remnant syndrome in bitches and queens: Clinical aspects and potential neoplastic transformations. Animals, 15(21), 3106. https://doi. org/10.3390/ani15213106
  22. Sasidharan, JK., Patra, MK., Singh, LK., Saxena, AC., De, UK., Singh, V.,.Krishnaswamy, N. (2021). Ovarian cysts in the bitch: An update. Topics in Companion Animal Medicine, 43, 100511. https://doi.org/10.1016/j. tcam.2021.100511