AI Summary & Key Takeaways
AI InsightConclusion: This study is the first to detect increased dispersions of P wave and Tp-e intervals (without an increase in QTc disp.) during the evaluation of atrial and ventricular arrhythmia risks during COPD acute attacks.
📌 3 Key Takeaways
Özet
Objective: Hypoxemia, hypercapnia, and increased automaticity during exacerbations contribute to abnormal atrial and ventricular repolarization in chronic obstructive pulmonary disease (COPD), raising the risk of arrhythmias. This study aimed to predict the likelihood of arrhythmias by analyzing electrocardiograms (ECGs) of patients experiencing COPD attacks. Material and Methods: A total of 120 patients (66 in the COPD group and 54 in the control group) were included. Statistical analysis compared QT and QTc interval maximum (max), minimum (min), and dispersion (disp); T-wave peak to end (Tp-e) max, min, and disp; Tp-e max/QT max, Tp-e max/QTc max ratios; and P wave max, min, and disp durations among patients. Results: Of the males in the study, 48 (64%) were in the COPD group and 27 (36%) in the control group, while 18 (40%) of the females were in the COPD group and 27 (60%) in the control group. There were no significant differences in patient ages or levels of sodium and potassium (p = 0.189, 0.353, and 0.071). Significant differences were found in QT max and min between groups, while QT disp showed no significant difference (p < 0.001, p < 0.001, and p = 0.490). Tp-e max, min, and disp values differed significantly between the COPD and control groups (p = 0.041, p < 0.001, and p = 0.001, respectively). No significant difference was observed between groups in terms of P max duration (p = 0.442), but significant differences were found in P min and disp durations (p = 0.003 and p < 0.001, respectively). Receiver operating characteristic analysis identified 30 ms as the cutoff for both P disp and Tp-e disp values, showing a significant difference. Conclusion: This study is the first to detect increased dispersions of P wave and Tp-e intervals (without an increase in QTc disp.) during the evaluation of atrial and ventricular arrhythmia risks during COPD acute attacks.