Journals / Bozok Tıp Dergisi / 2025 / Cilt: 15 Sayı: 4

THE EFFECT OF VARICOCELECTOMY ON SEMEN PARAMETERS IN INFERTILE PATIENTS

İNFERTİL HASTALARDA UYGULANAN VARİKOSELEKTOMİNİN SPERMİOGRAM PARAMETRELERİNE ETKİSİ

Mostafa Sultanı Afghan(YOZGAT BOZOK ÜNİVERSİTESİ)0000-0001-6508-0628
Mehmet Caniklioğlu(YOZGAT BOZOK ÜNİVERSİTESİ)0000-0003-2216-5677
Volkan Selmi(YOZGAT BOZOK ÜNİVERSİTESİ)0000-0003-2605-9935
Ayşen Caniklioğlu(YOZGAT BOZOK ÜNİVERSİTESİ)0000-0001-8128-6044
Pages
491–495
Publication Date
2025-12-15
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These findings have important implications for clinical decision-making, both in preparing patients for assisted reproductive techniques and in enhancing the potential for natural conception.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim : Varicocele is one of the most significant treatable causes of male infertility.
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Key Findings & Data:Materials and Methods: The study retrospectively evaluated data from patients aged 18–40 years who presented to the urology outpatient clinic with primary infertility and underwent varicocelectomy for at least grade 2 varicocele.
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Conclusion & Impact:These findings have important implications for clinical decision-making, both in preparing patients for assisted reproductive techniques and in enhancing the potential for natural conception.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Varikosel · varikoselektomi · infertilite

Abstract

Aim : Varicocele is one of the most significant treatable causes of male infertility. It contributes to infertility through various mechanisms, the most frequently implicated being elevated scrotal temperature and oxidative stress. Varicocelectomy aims to mitigate these effects and thereby enhance fertility potential. This study aimed to evaluate whether varicocelectomy in infertile patients leads to improvements in semen parameters. Materials and Methods: The study retrospectively evaluated data from patients aged 18–40 years who presented to the urology outpatient clinic with primary infertility and underwent varicocelectomy for at least grade 2 varicocele. Recorded semen parameters included semen volume, total sperm count, sperm concentration, percentage of progressively motile sperm, and total motile sperm percentage. Preoperative and postoperative semen analysis results were compared. Results: Analysis of 110 patients revealed statistically significant postoperative improvements in total sperm count (p<0.001), sperm concentration (p<0.001), percentage of progressively motile sperm (p=0.007), and total motile sperm percentage (p=0.044). No significant change was observed in semen volume (p=0.150). Conclusion: While many studies emphasize the positive effects of varicocelectomy, some argue that varicocele has no substantial impact on fertility and that its treatment may not contribute to improved fertility outcomes. Our study supports the notion that varicocelectomy yields statistically and clinically significant improvements in semen parameters and sperm quality in patients with primary infertility. These findings have important implications for clinical decision-making, both in preparing patients for assisted reproductive techniques and in enhancing the potential for natural conception.

Özet

Amaç: Varikosel erkek infertilitesinin tedavi edilebilir en önemli nedenlerinden biridir. Varikosel çeşitli mekanizmalarla infertiliteye sebebiyet vermekte olup en çok suçlanan mekanizmalar yüksek ısı ve oksidatif strestir. Varikoselektomi ile bu etkilerin önüne geçilerek fertiliteye katkı sağlanmaktadır. Çalışmamızda infertil hastalarda yapılan varikoselektominin semen parametrelerinde iyileşmeye katkısı olup olmadığını değerlendirmek amaçlanmıştır. Gereç-Yöntem: Primer infertilite nedeniyle üroloji polikliniğine başvuran ve en az grade 2 varikoseli olup varikoselektomi yapılmış olan 18-40 yaşları arasında hastaların sistemde kayıtlı olan verileri retrospektif olarak değerlendirildi. Hastaların semen analizlerinde semen hacmi, total sperm sayısı, sperm konsantrasyonu, ileri hareketli sperm yüzdeleri ve toplam hareketli sperm oranları semen parametreleri olarak kayıt altına alındı. Hastaların spermiogram değerleri preoperatif ve postoperatif olarak karşılaştırıldı. Bulgular: İncelenen 110 hastanın operasyon öncesi ve sonrası bakılan semen parametrelerinde toplam sperm sayısı (p<0,001), sperm konsantrasyonu (p<0,001), ileri hareketli sperm oranları (p=0,007) ve total hareketli sperm oranlarında (p=0,044) postoperatif anlamlı artış vardı. Semen volümlerinde anlamlı değişiklik yoktu.(p=0,150) Sonuç: Yapılan çalışmaların çoğu varikoselektominin olumlu sonuçlarından bahsederken varikoselin infertilite üzerine etkisi ve tedavisinin fertiliteye katkısı olmadığını savunanlar da vardır. Çalışmamız varikoselektominin primer infertil hastalarda semen parametreleri ve sperm kalitesi üzerinde anlamlı ve klinik açıdan değerli etkileri olduğunu desteklemektedir. Bu veriler, hem yardımcı üreme tekniklerine hazırlık hem de doğal yolla gebe kalma şansının artırılması bağlamında klinik kararları desteklemektedir.

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Cite This Article

Taşpınar, M. Ş., Afghan, M. S., Caniklioğlu, M., Selmi, V., Caniklioğlu, A. (2025). THE EFFECT OF VARICOCELECTOMY ON SEMEN PARAMETERS IN INFERTILE PATIENTS. Bozok Tıp Dergisi, Cilt: 15 Sayı: 4, 491–495. https://doi.org/10.16919/bozoktip.1790500

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