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Journals / Bozok Tıp Dergisi / 2026 / Cilt: 16 Sayı: 3

Arterial Vascular Anatomy of the Upper Thoracic–Lower Cervical Spinal Cord in Guinea Pigs:A Corrosion Cast Study

KOBAYDA MEDULLA SPİNALİS’İN ÜST TORAKAL– ALT SERVİKAL BÖLGESİNİN ARTERİYEL VASKÜLER ANATOMİSİNİN KOROZYON KAST YÖNTEMİ İLE İNCELENMESİ

Bahadır Murat Demirel(BOZOK ÜNİVERSİTESİ)0000-0002-5869-9753
Levent Sarıkçıoğlu(AKDENİZ ÜNİVERSİTESİ)0000-0002-0825-6225
Fatoş Belgin Yıldırım(AKDENİZ ÜNİVERSİTESİ)0000-0002-1939-6936
Yaşar Uçar(AKDENİZ ÜNİVERSİTESİ)0009-0009-5487-0929
Nurettin Oğuz(AKDENİZ ÜNİVERSİTESİ)0000-0001-6864-8872
Pages
412–422
Publication Date
2026-09-25
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These findings may provide anatomical insight for experimental spinal cord studies and spinal surgical procedures.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of this study was to investigate the arterial vascular anatomy of the upper thoracic–lower cervical region of the guinea pig spinal cord using the corrosion cast technique and to evaluate the collateral circulation of this region.
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Key Findings & Data:After polymerization, tissues were macerated to obtain vascular casts.
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Conclusion & Impact:These findings may provide anatomical insight for experimental spinal cord studies and spinal surgical procedures.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Medulla Spinalis · Kobay · Damar Sistemi

Abstract

Objective: The aim of this study was to investigate the arterial vascular anatomy of the upper thoracic–lower cervical region of the guinea pig spinal cord using the corrosion cast technique and to evaluate the collateral circulation of this region. Material and Methods: Twenty adult male guinea pigs were included in the study. Following perfusion and fixation procedures, Takilon- and Mercox-based corrosion cast materials were injected into the vascular system. After polymerization, tissues were macerated to obtain vascular casts. The specimens were examined and photographed under a stereomicroscope. Results: The guinea pig spinal cord was supplied by the anterior spinal artery, posterior spinal artery, anterolateral spinal artery, posterolateral spinal artery, and vertebral artery. Arterial vascularization of the upper thoracic–lower cervical region was weaker compared with the other spinal segments. However, numerous anastomotic connections were observed between the longitudinal arteries. The anterior spinal artery showed deviation from the midline in most specimens. Tortuous courses and vascular variations were also detected in some preparations. Conclusion: The vascular structures of the upper thoracic–lower cervical spinal cord in guinea pigs showed similarities to human spinal cord anatomy. Anastomotic connections between longitudinal arteries may contribute to collateral circulation. These findings may provide anatomical insight for experimental spinal cord studies and spinal surgical procedures.

Özet

Amaç: Bu çalışmada kobay medulla spinalis’in üst torakal–alt servikal bölgesinin arteriyel vasküler anatomisinin korozyon kast yöntemi kullanılarak üç boyutlu olarak ortaya konulması amaçlandı. Ayrıca bölgedeki kollateral dolaşım özelliklerinin değerlendirilmesi hedeflendi. Gereç ve Yöntemler: Çalışmada 20 erişkin erkek kobay kullanıldı. Perfüzyon ve fiksasyon işlemlerinin ardından damar sistemine Takilon ve Mercox esaslı korozyon kast materyalleri enjekte edildi. Polimerizasyon sonrası dokular masere edilerek vasküler kalıplar elde edildi. Preparatlar stereomikroskop altında incelendi ve fotoğraflandı. Bulgular: Kobay medulla spinalis’inin a. spinalis anterior, a. spinalis posterior, a. spinalis anterolateralis, a. spinalis posterolateralis ve a. vertebralis tarafından beslendiği gözlendi. Alt servikal–üst torakal bölgede arteriyel yoğunluğun diğer segmentlere göre daha zayıf olduğu saptandı. Bununla birlikte longitudinal damarlar arasında çok sayıda anastomotik bağlantı bulunduğu görüldü. A. spinalis anterior’un çoğu olguda orta hattan deviasyon gösterdiği belirlendi. Bazı preparatlarda ise kıvrımlı seyir ve varyasyonlar gözlendi. Sonuç: Kobay spinal kordunun üst torakal–alt servikal bölgesindeki vasküler yapıların insan anatomisi ile benzer özellikler taşıdığı görüldü. Longitudinal damarlar arasındaki anastomozların kollateral dolaşıma katkı sağlayabileceği değerlendirildi. Elde edilen bulguların deneysel spinal kord çalışmaları ve spinal cerrahi girişimler açısından anatomik katkı sağlayabileceği düşünülmektedir.

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Cite This Article

Demirel, B. M., Sarıkçıoğlu, L., Yıldırım, F. B., Uçar, Y., Oğuz, N. (2026). Arterial Vascular Anatomy of the Upper Thoracic–Lower Cervical Spinal Cord in Guinea Pigs:A Corrosion Cast Study. Bozok Tıp Dergisi, Cilt: 16 Sayı: 3, 412–422. https://doi.org/10.16919/bozoktip.1961627

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