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Journals / Acta Medica Nicomedia / 2024 / Cilt: 7 Sayı: 3

Fragmented QRS Pattern Predicts Poor Prognosis in Sepsis and Septic Shock

Fragmente QRS Paterni Sepsis ve Septik Şokta Kötü Prognozu Öngörür

Pınar Karabacak(SÜLEYMAN DEMİREL ÜNİVERSİTESİ, TIP FAKÜLTESİ, CERRAHİ TIP BİLİMLERİ BÖLÜMÜ, ANESTEZİYOLOJİ VE REANİMASYON ANABİLİM DALI, YOĞUN BAKIM BİLİM DALI)0000-0002-6210-5962
Mustafa Karabacak(SÜLEYMAN DEMİREL ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, KARDİYOLOJİ ANABİLİM DALI)0000-0001-6879-5522
Özlem Polat(İSTANBUL ÜNİVERSİTESİ TIP FAKÜLTESİ CERRAHİ TIP BİLİMLERİ BÖLÜMÜ, ANESTEZİYOLOJİ VE REANİMASYON ANABİLİM DALI YOĞUN BAKIM BİLİM DALI)0000-0003-3806-5574
Yağmur Kara(ISPARTA ŞEHİR HASTANESİ YOĞUN BAKIM KLİNİĞİ)0000-0003-4117-0455
Pages
257–262
Publication Date
2024-10-27
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This study aimed to determine whether fQRS patterns were associated with short-term overall survival(OS).

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Myocardial dysfunction due to sepsis is a clinical condition associated with a high rate of mortality.
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Key Findings & Data:Methods: 76 patients with sepsis and 68 patients with septic shock were included in the study.
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Conclusion & Impact:This study aimed to determine whether fQRS patterns were associated with short-term overall survival(OS).
🔬Design:Klinik Araştırma
📍Scope:Comprehensive Sample
⚙️Variables:Sepsis · Septik Şok · Elektrokardiyografi

Abstract

Objective: Myocardial dysfunction due to sepsis is a clinical condition associated with a high rate of mortality. Fragmented QRS (fQRS) is a marker that is associated with the function of the myocardium. This study aimed to determine whether fQRS patterns were associated with short-term overall survival(OS). Methods: 76 patients with sepsis and 68 patients with septic shock were included in the study. SOFA score and APACHE II score were calculated, and the fQRS pattern has been assessed.. Results: In the septic shock group, APACHE II score, SOFA score and mortality were significantly higher [38 (%50) vs 45 (%65), respectively; p<0.01]. Duration of mechanical ventilation, the fQRS pattern, and hospitalization time predicted the mortality. The fQRS pattern's presence was linked to a decreased short-term survival in both groups Conclusion: fQRS pattern and mortality were significantly higher especially septic shocks. However, in both groups, the presence of the fQRS has been found to have a correlation with mortality and independently predicted worse OS. Thus, we propose that the fQRS pattern could serve as a novel prognostic indicator for septic patients.

Özet

Amaç: Sepsise bağlı miyokardiyal disfonksiyon, yüksek mortalite oranı ile ilişkili klinik bir durumdur. Parçalanmış QRS (fQRS) miyokardın fonksiyonu ile ilişkili bir belirteçtir. Bu çalışmanın amacı fQRS paternlerinin kısa dönem genel sağkalım (OS) ile ilişkili olup olmadığını belirlemektir. Yöntem: Çalışmaya 76 sepsis ve 68 septik şok hastası dahil edildi. SOFA skoru ve APACHE II skoru hesaplandı ve fQRS paterni değerlendirildi. Bulgular: Septik şok grubunda APACHE II skoru, SOFA skoru ve mortalite anlamlı olarak daha yüksekti [sırasıyla 38 (%50) vs 45 (%65); p<0.01]. Mekanik ventilasyon süresi, fQRS paterni ve hastanede yatış süresi mortaliteyi öngörmüştür. FQRS paterninin varlığı her iki grupta da kısa dönem sağkalımda azalma ile ilişkilendirilmiştir Sonuç: fQRS paterni ve mortalite özellikle septik şoklarda anlamlı olarak daha yüksekti. Bununla birlikte, her iki grupta da fQRS varlığının mortalite ile korelasyon gösterdiği ve bağımsız olarak daha kötü OS'yi öngördüğü bulunmuştur. Bu nedenle, fQRS paterninin septik hastalar için yeni bir prognostik gösterge olabileceğini düşünüyoruz.

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Cite This Article

Karabacak, P., Karabacak, M., Polat, Ö., Kara, Y. (2024). Fragmented QRS Pattern Predicts Poor Prognosis in Sepsis and Septic Shock. Acta Medica Nicomedia, Cilt: 7 Sayı: 3, 257–262. https://ajindex.com/articles/1351372

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