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Journals / Abant Tıp Dergisi / 2026 / Cilt: 15 Sayı: 1

The Relationship Between Vitamin B12 Level and Activities of Daily Living, Physical and Cognitive Frailty in Geriatric Patients

Hasan Çöl(KUTAHYA HEALTH SCIENCES UNIVERSITY)0000-0003-2159-1455
Çağla Özdemir(Kütahya Sağlık Bilimleri Üniversitesi)0000-0002-9766-1918
Adem Durmaz(KUTAHYA HEALTH SCIENCES UNIVERSITY)0000-0001-5890-3622
Yasemin Korkut Kurtoğlu(KUTAHYA HEALTH SCIENCES UNIVERSITY)0000-0002-8293-8590
Pages
1–12
Publication Date
2026-04-30
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, a substantial negative correlation was identified between albumin, iron and hemoglobin levels and physical and cognitive frailty and a significant positive correlation between activities of daily living.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Investigate the relationship between vitamin B12 levels and activities of daily living, physical and cognitive frailty in older people.
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Key Findings & Data:Materials and Methods: In this cross-sectional study, patients aged 65 years and older who met the inclusion and exclusion criteria and who were seen in the outpatient clinics of the Family Medicine Department between 01.01-01.05.2023 were included.
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Conclusion & Impact:However, a substantial negative correlation was identified between albumin, iron and hemoglobin levels and physical and cognitive frailty and a significant positive correlation between activities of daily living.
🔬Design:Araştırma Makalesi
📍Scope:2023 Verileri
⚙️Variables:Elderly · Vitamin B12 · Physical Frailty

Abstract

Objective: Investigate the relationship between vitamin B12 levels and activities of daily living, physical and cognitive frailty in older people. Materials and Methods: In this cross-sectional study, patients aged 65 years and older who met the inclusion and exclusion criteria and who were seen in the outpatient clinics of the Family Medicine Department between 01.01-01.05.2023 were included. Current biochemical blood parameters of the patients were recorded. Sociodemographic form, FRAIL and Edmonton Frailty Scale, Mini Mental State Test, Modified Charlson Comorbidity Index, Katz Activities of Daily Living and Lawton-Brody Instrumental Activities of Daily Living Scales were administered by face-to-face interview method. Statistical significance level was accepted as p<0.05. Results: The study included a total of 264 participants. %65.5 of the participants were female. The median age of the participants was 70 (65-88) years.%31.8 of the participants were found to be frail according to FRAIL scale and %29.1 according to Edmonton scale. When evaluated with the Mini Mental Test, %48.1 had cognitive dysfunction. The mean vitamin B12 level was 210 ng/l. No correlation was found between vitamin B12 level and FRAIL and Edmonton Frailty Scale, KATZ and Lawton-Brody Activities of Daily Living Scale, Modified Charlson Comorbidity Index and Mini Mental Test scores. A considerable negative correlation was identified betweenalbumin, iron and haemoglobin levels and physical and cognitive frailty, whereas a substantial and positive correlation was ascertained withactivities of daily living. Conclusion: In the present study, the investigation revealed no association between vitamin B12 concentrationsand activities of daily living, physical and cognitive frailty in geriatric patients. However, a substantial negative correlation was identified between albumin, iron and hemoglobin levels and physical and cognitive frailty and a significant positive correlation between activities of daily living.

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Cite This Article

Çöl, H., Özdemir, Ç., Durmaz, A., Kurtoğlu, Y. K. (2026). The Relationship Between Vitamin B12 Level and Activities of Daily Living, Physical and Cognitive Frailty in Geriatric Patients. Abant Tıp Dergisi, Cilt: 15 Sayı: 1, 1–12. https://doi.org/10.47493/abantmedj.1706658

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