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Journals / Acta Medica Alanya / 2026 / Cilt: 5 Sayı: 2

Antibacterial effects of leukocyte and platelet-rich fibrin against Escherichia coli and Enterococcus faecalis

Lökosit ve Trombositten Zengin Fibrinin Escherichia Coli’ye ve Enterococcus Faecalis'e Karşı Antibakteriyel Etkileri

Mehtap Bilgin Çetin(Başkent Üniversitesi, Diş Hekimliği Fakültesi, Periodontoloji Anabilim Dalı)0000-0003-3164-6886
Yasemin Sezgin(Başkent Üniversitesi, Diş Hekimliği Fakültesi, Periodontoloji Anabilim Dalı)0000-0002-4732-805X
Ebru Evren(Ankara University Department of Medical Microbiology)0000-0001-7615-0521
Prof. Dr. Şule Bulut(Başkent Üniversitesi, Diş Hekimliği Fakültesi, Periodontoloji Anabilim Dalı)0000-0002-8808-0185
Pages
132–137
Publication Date
2021-08-30
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: L-PRF demonstrated no inhibition zone against E. coli and E. faecalis.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: The main goal of this research was to explore the in-vitro antibacterial characteristics of leukocyte and platelet-rich fibrin (L-PRF) against Escherichia coli (E.
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Key Findings & Data:Materials and methods: The study was conducted on 21 patients (10 females, 11 males, age range 21-32 years).
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Conclusion & Impact:Conclusion: L-PRF demonstrated no inhibition zone against E. coli and E. faecalis.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Antibakteriyel · Escherichia Coli · Enterococcus Faecalis

Abstract

Aim: The main goal of this research was to explore the in-vitro antibacterial characteristics of leukocyte and platelet-rich fibrin (L-PRF) against Escherichia coli (E. Coli) and Enterococcus faecalis (E. Faecalis). Materials and methods: The study was conducted on 21 patients (10 females, 11 males, age range 21-32 years). L-PRF was prepared from the participants’ own blood. Antibacterial activity of L-PRF against E. coli and E. faecalis ATCC standard strains was analyzed using the Kirby Bauer disk diffusion method. Results: The inhibition zones with PRF had not been detected even though the results obtained using control discs were in accordance with the expectations. Conclusion: L-PRF demonstrated no inhibition zone against E. coli and E. faecalis.

Özet

Amaç: Bu çalışmanın amacı, lökosit ve trombositten zengin fibrinin (TZF) Escherichia coli’ye (E. Coli) ve Enterococcus faecalis'e (E. Faecalis) karşı in vitro antibakteriyel etkilerini araştırmaktır. Gereç ve yöntemler: Çalışma 21 hasta (10 kadın, 11 erkek, yaş aralığı 21-32 yaş) üzerinde yürütülmüştür. Katılımcılardan elde edilen kan örnekleri kullanılarak TZF hazırlanmıştır. TZF'nin E. coli ve E. faecalis ATCC standart suşlarına antibakteriyel aktivitesi Kirby Bauer disk difüzyon yöntemi kullanılarak test edilmiştir. Bulgular: Beklenen sonuçlar kontrol diski ile elde edilmesine rağmen, TZF’nin değerlendirilen bakterilere karşı inhibisyon zonu göstermediği tespit edilmiştir. Sonuç: TZF, E.coli’ye ve E. faecalis’e karşı inhibisyon bölgesi göstermemiştir.

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Cite This Article

Çetin, M. B., Sezgin, Y., Evren, E., Bulut, P. D. Ş. (2021). Antibacterial effects of leukocyte and platelet-rich fibrin against Escherichia coli and Enterococcus faecalis. Acta Medica Alanya, Cilt: 5 Sayı: 2, 132–137. https://doi.org/10.30565/medalanya.850173

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