SavedAdd your journal

Journals / Acta Medica Alanya / 2026 / Cilt: 10 Sayı: 2

Retrospective Evaluation of Changes in Subfoveal CVI, Choroidal and Macular Thickness After Nd:YAG Laser Capsulotomy

Nd:YAG Lazer Kapsülotomi Sonrası Subfoveal CVI, Koroid ve Makula Kalınlığı Değişikliklerinin Retrospektif Olarak Değerlendirilmesi

Elmas Yüksel Şükün(Alanya Eğitim ve Araştırma Hastanesi)0000-0003-3320-3739
Sibel Sipahioğlu(Alanya Eğitim ve Araştırma Hastanesi)0000-0001-6506-6885
Beyza Yılıdır(ALANYA ALAADDİN KEYKUBAT ÜNİVERSİTESİ)0009-0003-7460-7569
Nedime Sahinoglu Keskek(ALANYA ALAADDİN KEYKUBAT ÜNİVERSİTESİ)0000-0001-8544-103X
Pages
166–171
Publication Date
2026-08-16
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The correlation between laser energy and CVI suggests that CVI may serve as a potential biomarker reflecting early choroidal microvascular response and inflammation following the procedure.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: This study aimed to evaluate early postoperative changes in subfoveal choroidal vascularity index (CVI), subfoveal choroidal thickness (CT), and central macular thickness (CMT) after Nd:YAG laser capsulotomy performed for posterior capsule opacification (PCO).
📊
Key Findings & Data:Methods: This retrospective study included 42 eyes of 42 patients who underwent Nd:YAG laser capsulotomy between January 2023 and May 2025.
💡
Conclusion & Impact:The correlation between laser energy and CVI suggests that CVI may serve as a potential biomarker reflecting early choroidal microvascular response and inflammation following the procedure.
🔬Design:Araştırma Makalesi
📍Scope:2023 Verileri
⚙️Variables:Nd:YAG lazer kapsülotomi · Posterior kapsül opasifikasyonu · Koroidal vaskülarite indeksi

Abstract

Aim: This study aimed to evaluate early postoperative changes in subfoveal choroidal vascularity index (CVI), subfoveal choroidal thickness (CT), and central macular thickness (CMT) after Nd:YAG laser capsulotomy performed for posterior capsule opacification (PCO). Methods: This retrospective study included 42 eyes of 42 patients who underwent Nd:YAG laser capsulotomy between January 2023 and May 2025. Biometric measurements were obtained using the RTVue XR SD-OCT device preoperatively and at 1 month postoperatively. CVI was calculated using manual segmentation and binarization on ImageJ software. Results: Significant increases were observed in CVI, CT, and CMT values at 1 month postoperatively (all p<0.05). The increase in CVI showed a moderate positive correlation with the total laser energy applied (ρ=0.541, p<0.05). However, no significant correlation was found between laser energy and changes in CT or CMT. Conclusion: Nd:YAG laser capsulotomy was associated with significant early increases in subfoveal CVI, choroidal thickness, and macular thickness. The correlation between laser energy and CVI suggests that CVI may serve as a potential biomarker reflecting early choroidal microvascular response and inflammation following the procedure.

Özet

Amaç: Bu çalışmanın amacı, posterior kapsül opasifikasyonu (PCO) nedeniyle Nd:YAG lazer kapsülotomi uygulanan hastalarda subfoveal koroidal vaskülarite indeksi (CVI), subfoveal koroid kalınlığı (CT) ve santral makula kalınlığı (CMT) değerlerinde meydana gelen erken dönem değişiklikleri değerlendirmektir. Yöntem: Bu retrospektif çalışmaya, Ocak 2023 – Mayıs 2025 tarihleri arasında PCO tanısıyla Nd:YAG lazer kapsülotomi uygulanan 42 hastanın 42 gözü dahil edilmiştir. Biyometrik ölçümler RTVue XR SD-OCT cihazı kullanılarak kapsülotomi öncesi ve işlem sonrası 1. ayda yapılmıştır. CVI hesaplamaları ImageJ yazılımı kullanılarak manuel segmentasyon ve binarizasyon yöntemleriyle gerçekleştirilmiştir. Bulgular: Postoperatif 1. ayda CVI, CT ve CMT değerlerinde istatistiksel olarak anlamlı artış saptanmıştır (tümü için p<0,05). CVI’deki artış, uygulanan toplam lazer enerjisi ile orta düzeyde pozitif korelasyon göstermiştir (ρ=0.541, p<0.05). Ancak CT ve CMT’deki değişimlerle enerji düzeyleri arasında anlamlı ilişki bulunmamıştır. Sonuç: Nd:YAG lazer kapsülotomi sonrası subfoveal CVI, koroid kalınlığı ve makula kalınlığında erken dönemde anlamlı artışlar gözlenmiştir. Özellikle CVI’deki artışın lazer enerjisiyle ilişkili bulunması, bu parametrenin arka segment inflamasyonunu yansıtan potansiyel bir biyobelirteç olabileceğini düşündürmektedir.

🔖

Cite This Article

Şükün, E. Y., Sipahioğlu, S., Yılıdır, B., Keskek, N. S. (2026). Retrospective Evaluation of Changes in Subfoveal CVI, Choroidal and Macular Thickness After Nd:YAG Laser Capsulotomy. Acta Medica Alanya, Cilt: 10 Sayı: 2, 166–171. https://doi.org/10.30565/medalanya.1909092

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Wormstone IM, Eldred JA. Experimental models for posterior capsule opacification research. Exp Eye Res. 2016;142:2-12. doi: 10.1016/j.exer.2015.04.021.
  2. Wang Y, Cao K, Li M, Wan XH. Posterior capsular opacification: pathogenesis, challenges, and innovative therapeutic strategies. Exp Eye Res. 2025;259:110585. doi: 10.1016/j.exer.2025.110585.
  3. Awasthi N, Guo S, Wagner BJ. Posterior capsular opacification: a problem reduced but not yet eradicated. Arch Ophthalmol. 2009;127(4):555-62. doi: 10.1001/archophthalmol.2009.3.
  4. Aslam TM, Devlin H, Dhillon B. Use of Nd:YAG laser capsulotomy. Surv Ophthalmol. 2003;48(6):594-612. doi: 10.1016/j.survophthal.2003.08.002.
  5. Urfalıoglu S, Özdemir G, Güler M, Daghan B, Öz F. The evaluation of the effect of Nd-YAG capsulotomy on posterior ocular vascular structures by optical coherence tomography angiography. Photodiagnosis Photodyn Ther. 2023;42:103323. doi: 10.1016/j.pdpdt.2023.103323.
  6. Ari S, Cingü AK, Sahin A, Çınar Y, Çaça I. The effects of Nd:YAG laser posterior capsulotomy on macular thickness, intraocular pressure, and visual acuity. Ophthalmic Surg Lasers Imaging. 2012;43(5):395-400. doi: 10.3928/15428877-20120705-03.
  7. Yilmaz T, Yilmaz A. Long-term changes in subfoveal choroidal thickness and central macula thickness after Nd:YAG laser capsulotomy. Int Ophthalmol. 2017;37(4):1003-1008. doi: 10.1007/s10792-016-0353-x.
  8. Gore VS. The study of complications of ND:YAG laser capsulotomy. Int J Bioinform Res. 2012;4(2):265-8. doi: 10.9735/0975-3087.4.2.265-268.
  9. Javitt JC, Tielsch JM, Canner JK, Kolb MM, Sommer A, Steinberg EP. National outcomes of cataract extraction: increased risk of retinal complications associated with Nd:YAG laser capsulotomy. Ophthalmology. 1992;99(10):1487-97. doi: 10.1016/S0161-6420(92)31775-0.
  10. Agrawal R, Gupta P, Tan KA, Cheung CM, Wong TY, Cheng CY. Choroidal vascularity index as a measure of vascular status of the choroid: Measurements in healthy eyes from a population-based study. Sci Rep. 2016;6:21090. doi: 10.1038/srep21090.
  11. Küçük E, Yeşilyurt H, Çakmak M, Zor KR, Karataş MÇ. Evaluation of the effects of ND:YAG laser capsulotomy on choroidal thickness and choroidal vascularity index. Lasers Med Sci. 2025. doi: 10.1007/s10103-025-04379-x.
  12. Icoz M, Tarım B, Icoz SGG. The effect of Nd:YAG Laser applied in the posterior capsule opacification on retinal and choroidal structures. Photodiagnosis Photodyn Ther. 2023;43:103653. doi: 10.1016/j.pdpdt.2023.103653.
  13. Karahan E, Tuncer I, Zengin MO. The effect of ND:YAG laser posterior capsulotomy size on refraction, intraocular pressure, and macular thickness. J Ophthalmol. 2014;2014:846385. doi: 10.1155/2014/846385.
  14. Mansoori T, Charan ASR, Nagalla B. Topography and choroidal thickness measurement in healthy Asian Indian subjects using RTVue XR 100 optical coherence tomography. Middle East Afr J Ophthalmol. 2024;30(1):19-23. doi: 10.4103/meajo.meajo_89_23.
  15. Nickla DL, Wallman J. The multifunctional choroid. Prog Retin Eye Res. 2010;29(2):144-68. doi: 10.1016/j.preteyeres.2009.12.002.
  16. Wei WB, Xu L, Jonas JB, Shao L, Du KF, Wang YX. Subfoveal choroidal thickness: the Beijing Eye Study. Ophthalmology. 2013;120(1):175-80. doi: 10.1016/j.ophtha.2012.07.048.