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Journals / Düzce Tıp Fakültesi Dergisi / 2026 / Volume: 28 Issue: 2

ALADAPA Syndrome: An Insidious Trigger for Fatal Acute Coronary Syndrome Following Oral Contraceptive Overdose

Fahri Çakan(ALANYA ALAADDIN KEYKUBAT UNIVERSITY, FACULTY OF MEDICINE)0000-0002-5427-3480
Hasan Tolga Özer(Çorlu State Hospital)0009-0001-8704-5353
Pages
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Publication Date
2026-08-21
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this case report, we describe a fatal instance of ALADAPA syndrome, diagnosed for the first time post-cardiac arrest in a young woman following the use of high-dose oral contraceptive pills for emergency contraception.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital anomaly associated with a high risk of adverse cardiac events and mortality.
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Key Findings & Data:The isolated origin of the left anterior descending artery from the pulmonary artery (ALADAPA) is even more infrequent.
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Conclusion & Impact:In this case report, we describe a fatal instance of ALADAPA syndrome, diagnosed for the first time post-cardiac arrest in a young woman following the use of high-dose oral contraceptive pills for emergency contraception.
🔬Design:Case Report
📍Scope:Comprehensive Sample
⚙️Variables:ALADAPA syndrome · anomalous left anterior descending coronary artery · contraceptive pill

Abstract

The anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital anomaly associated with a high risk of adverse cardiac events and mortality. The isolated origin of the left anterior descending artery from the pulmonary artery (ALADAPA) is even more infrequent. Although the clinical course is generally quieter than the classic ALCAPA syndrome, it carries a high risk of sudden cardiac death. Conditions that predispose individuals to thrombogenicity can precipitate this insidious condition. In this case report, we describe a fatal instance of ALADAPA syndrome, diagnosed for the first time post-cardiac arrest in a young woman following the use of high-dose oral contraceptive pills for emergency contraception.

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Cite This Article

Çakan, F., Özer, H. T. (2026). ALADAPA Syndrome: An Insidious Trigger for Fatal Acute Coronary Syndrome Following Oral Contraceptive Overdose. Düzce Tıp Fakültesi Dergisi, Volume: 28 Issue: 2. https://doi.org/10.18678/dtfd.1889028

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