Journals / Journal of Emergency Medicine Case Reports / 2026 / Cilt: 17 Sayı: 1

A Complex Cause of Bradycardia: BRASH Syndrome

Bradikardinin Kompleks Bir Nedeni: BRASH Sendromu

Dilara Cari Güngör(University of Health Sciences, Konya City Hospital, Neurology and Intensive Care Unit)0000-0002-4596-8213
Büşra Pekince(Konya Numune Hospital, Pulmonology and Intensive Care Unit)0000-0001-7525-7896
Yasemin Cebeci(University of Health Sciences, Beyhekim Training And Research Hospital, Anesthesiology-Reanimation and Intensive Care Unit)0000-0002-9934-8300
Yeşim Şerife Bayraktar(Selçuk University, Faculty of Medicine, Anesthesiology-Reanimation and Intensive Care Unit)0000-0001-5156-7064
Jale Bengi Çelik(Selçuk University, Faculty of Medicine, Anesthesiology-Reanimation and Intensive Care Unit)0000-0003-2167-9967
Pages
48–50
Publication Date
2026-03-31
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Finally, we created a graphical abstract summarizing this syndrome.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Abstract: BRASH syndrome is a definition that encompasses complex causes of bradycardia.
📊
Key Findings & Data:We presented the BRASH clinic in 84-year-old female patient and discussed the approach.
💡
Conclusion & Impact:Finally, we created a graphical abstract summarizing this syndrome.
🔬Design:Olgu Sunumu
📍Scope:Comprehensive Sample
⚙️Variables:Bradikardi · Atrioventriküler Nod Blokörleri · Renal Yetmezlik

Abstract

Abstract: BRASH syndrome is a definition that encompasses complex causes of bradycardia. The use of atrioventricular node blockers, renal failure, hypercalcemia, bradycardia, renal hypoperfusion create a cascade that triggers each other. Additionally, hyperkalemic drugs such as angiotensin converting enzyme inhibitors may aggrevate the clinical condition. This is a clinical condition that can lead to shock and mortality if the diagnosis and mechanism are not considered or overlooked. We presented the BRASH clinic in 84-year-old female patient and discussed the approach. Finally, we created a graphical abstract summarizing this syndrome.

Özet

Özet: BRASH sendromu bradikardinin complex nedenlerini kapsayan bir tanımlamadır. Atriovenriküler nod blokörleri kullanımı, renal yetmezlik, hiperkalsemi, bradikardi, renal hipoperfüzyon birbirini tetikleyen bir kaskad oluştururlar. Ek olarak, anjiyotensin dönüştürücü enzim inhibitörleri gibi hiperkalemik ilaçlar klinik durumu kötüleştirebilir. Tanı ve mekanizmanın düşünülmemesi veya gözden kaçırılması durumunda şok ve mortaliteye sebep olabilecek klinik bir durumdur. Biz 84 yaşındaki bir hastada BRASH kliniğini prezante ettik ve yaklaşımı tartıştık. Son olarak bu sendromu özetleyen grafiksel bir özet oluşturduk.

🔖

Cite This Article

Güngör, D. C., Pekince, B., Cebeci, Y., Bayraktar, Y. Ş., Çelik, J. B. (2026). A Complex Cause of Bradycardia: BRASH Syndrome. Journal of Emergency Medicine Case Reports, Cilt: 17 Sayı: 1, 48–50. https://doi.org/10.33706/jemcr.1790911

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (7)

  1. Shah P, Gozun M, Keitoku K, et al. Clinical characteristics of BRASH syndrome: Systematic scoping review. Eur J Intern Med 2022 Sep;103:57-61. doi: 10.1016/j.ejim.2022.06.002.
  2. Farkas JD, Long B, Koyfman A, Menson K. BRASH Syndrome: Bradycardia, Renal Failure, AV Blockade, Shock, and Hyperkalemia. J Emerg Med 2020 Aug;59(2):216-223. doi: 10.1016/j.jemermed.2020.05.001.
  3. Lizyness K, Dewald O. BRASH Syndrome. 2023 Mar 27. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 34033405.
  4. Roma N, Padala V, Pattoli M, et al. BRASH Syndrome: A Rare Clinical Phenomenon. CJC Open 2024 Apr 2;6(6):840-842. doi: 10.1016/j.cjco.2024.03.013.
  5. Majeed H, Khan U, Khan AM, et al. BRASH Syndrome: A Systematic Review of Reported Cases. Curr Probl Cardiol 2023 Jun;48(6):101663. doi: 10.1016/j.cpcardiol.2023.101663.
  6. Bailuni Neto JJ, Siqueira BL, Machado FC, et al. BRASH Syndrome: A Case Report. Am J Case Rep 2022 Jan 21;23:e934600. doi: 10.12659/AJCR.934600.
  7. Gebray HM, Abeje AE, Boye AT. BRASH syndrome with a complete heart block- a case report. BMC Cardiovasc Disord 2024 Feb 19;24(1):114. doi: 10.1186/s12872-024-0378