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Journals / The European Research Journal / 2026 / Volume: 5 Issue: 3

Comparison of laboratory and imaging methods associated with bone metabolism in patients with or without renal failure under the age of 45 years with elevated parathyroid hormone levels

Hande Peynirci(Department of Internal Medicine, Division of Endocrinology and Metabolism, Kanuni Sultan Süleyman Training and Research Hospital, İstanbul, Turkey)0000-0003-2631-8853
Canan Ersoy(Department of Internal Medicine, Division of Endocrinology and Metabolism, Uludağ University School of Medicine, Bursa, Turkey)0000-0003-4510-6282
Vildan Gürsoy(Department of Internal Medicine, Uludağ University School of Medicine, Bursa, Turkey)0000-0002-3645-9345
Ayten Girgin(Department of Internal Medicine, Uludağ University School of Medicine, Bursa, Turkey)0000-0002-2176-1912
Mehmet Ali Aşık(Department of Internal Medicine, Uludağ University School of Medicine, Bursa, Turkey)0000-0002-1631-6080
Ahmet Gültepe(Department of Internal Medicine, Uludağ University School of Medicine, Bursa, Turkey)0000-0001-7312-9137
Güven Özkaya(Department of Statistics, Uludağ University School of Medicine, Bursa, Turkey)0000-0003-0297-846X
Emel Isıktas Sayılar(Department of Internal Medicine, Division of Nephrology, Edirne State Hospital, Edirne, Turkey)0000-0002-8824-6560
Alpaslan Ersoy(Department of Internal Medicine, Division of Nephrology, Uludağ University School of Medicine, Bursa, Turkey)0000-0002-0710-0923
Pages
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Publication Date
2019-05-04
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: D ual energy X-ray absorptiometry seemed to be a reliable method for detection of osteoporosis in premenopausal female and male patients younger than 45 years of age with or without renal failure with elevated parathyroid hormone levels.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Although bone biopsy is considered the gold standard for the definitive diagnosis of renal osteodystrophy; it is not suitable for routine clinical practice due to its invasive nature.
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Key Findings & Data:Methods: This was a single center, cross-sectional, retrospective study conducted in patients younger than 45 years of age.
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Conclusion & Impact:Conclusion: D ual energy X-ray absorptiometry seemed to be a reliable method for detection of osteoporosis in premenopausal female and male patients younger than 45 years of age with or without renal failure with elevated parathyroid hormone levels.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:hyperparathyroidism · renal insufficiency · osteoporosis

Abstract

Objectives: Although bone biopsy is considered the gold standard for the definitive diagnosis of renal osteodystrophy; it is not suitable for routine clinical practice due to its invasive nature. The present study was aimed to evaluate and compare the bone mineral status using d ual energy X-ray absorptiometry of patients with or without chronic kidney disease in young population with elevated parathyroid hormone levels. Methods: This was a single center, cross-sectional, retrospective study conducted in patients younger than 45 years of age. The study was performed in the outpatient clinic of a university hospital. Patients with elevated parathyroid hormone levels were included. Results: Among them, 29 had renal insufficiency, 158 had normal renal function. Measured bone mineral density with d ual energy X-ray absorptiometry and laboratory values were collected from patient files. The primary end point was to assess the efficiacy of d ual energy X-ray absorptiometry in patients with or without renal failure. Except Z score at Ward’s triangle, all of the T and Z scores at lomber, femur neck, trochanteric, and inter trochanteric areas were found significantly lower in patients with chronic kidney disease compared to those without ( p < 0.001 ). Conclusion: D ual energy X-ray absorptiometry seemed to be a reliable method for detection of osteoporosis in premenopausal female and male patients younger than 45 years of age with or without renal failure with elevated parathyroid hormone levels.

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Cite This Article

Peynirci, H., Ersoy, C., Gürsoy, V., Girgin, A., Aşık, M. A., Gültepe, A., Özkaya, G., Sayılar, E. I., Ersoy, A. (2019). Comparison of laboratory and imaging methods associated with bone metabolism in patients with or without renal failure under the age of 45 years with elevated parathyroid hormone levels. The European Research Journal, Volume: 5 Issue: 3. https://doi.org/10.18621/eurj.378720

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