Journals / TSK Koruyucu Hekimlik Bülteni / 2011 / Cilt: 10 - Sayı: 4

[The Role of Oxygen Therapies in Carbon Monoxide Poisoning]

Karbonmonoksit Zehirlenmesinde Oksijen Tedavilerinin Rolü

Pages
487–494
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, it has been aimed to outline the significance of oxygen treatment modalities and to determine patient selection criteria for HBO treatment in the management of CO poisoning which continues to be an important threat to community health care

📌 3 Key Takeaways

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Objective & Hypothesis:Due to climate and socio-economic issues in Turkey, the incidence of carbon monoxide (CO) poisoning is high, especially in winter.
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Key Findings & Data:Clinical manifestations may vary depending on the type of CO source, concentration and duration of exposure.
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Conclusion & Impact:In this review, it has been aimed to outline the significance of oxygen treatment modalities and to determine patient selection criteria for HBO treatment in the management of CO poisoning which continues to be an important threat to community health care
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Due to climate and socio-economic issues in Turkey, the incidence of carbon monoxide (CO) poisoning is high, especially in winter. Clinical manifestations may vary depending on the type of CO source, concentration and duration of exposure. The symptoms of CO poisoning predominantly manifest in lots of organs and systems with high oxygen utilization, especially the brain and the heart. The primary aim in oxygen therapy is to eliminate CO and to reduce its toxic effects. In this context, normobaric and hyperbaric oxygen therapy are used to achieve these goals. Normobaric oxygen (NBO) treatment is an easily accessible and relatively not expensive modality, where hyperbaric oxygen (HBO) therapy requires specific equipment, certified staff and is available only in some centers. Additionally, HBO treatment has several additional advantages over NBO treatment. Despite its benefits, it is compulsory to search for some criteria in selecting patients to be treated because of the limited availability and access of hyperbaric facilities. For an effective evaluation and an optimal treatment, advanced education of the healthcare professionals on the use of oxygen delivery modalities in the management of CO poisoning is imperative. In this review, it has been aimed to outline the significance of oxygen treatment modalities and to determine patient selection criteria for HBO treatment in the management of CO poisoning which continues to be an important threat to community health care

Özet

Ülkemizde iklimsel ve sosyoekonomik nedenlerle, özellikle kış aylarında karbonmonoksit (CO) zehirlenmesi vakalarıyla sık karşılaşılmaktadır. CO zehirlenmesinde ortamdaki gazın miktarına, maruziyet süresine ve CO kaynağının tipine bağlı olarak farklı klinik formlar ortaya çıkmaktadır. CO gazı vücutta birçok sistemi etkilemektedir. Kalp ve beyin gibi oksijen gereksinimi yüksek olan organlar daha çok etkilenmektedir. Tedavide temel hedef, CO'nun eliminasyonu ve toksik etkilerinin azaltılmasıdır. Bu amaçla normobarik ve hiperbarik koşullarda uygulanan oksijen tedavileri kullanılmaktadır. Normobarik oksijen (NBO) tedavisi kolay ulaşılabilen, yaygın olarak kullanılan ve göreceli olarak maliyeti düşük olan bir tedavidir. Hiperbarik oksijen (HBO) tedavisi ise özgül cihazların kullanıldığı, eğitimli personele ihtiyaç duyulan ve az sayıda merkezde uygulanabilen bir tedavi yöntemidir. CO zehirlenmesinin tedavisinde HBO tedavisinin NBO tedavisine oranla üstünlükleri vardır. HBO tedavi merkezlerinin yeterli sayıda olmaması HBO tedavisi uygulanacak hastaları seçerken bazı kriterlerin aranmasını zorunlu kılmaktadır. Hekimlerimizin ve sağlık çalışanlarının CO zehirlenmesinde kullanılan oksijen tedavileri konusunda bilgilendirilmesi, hastaların etkin bir şekilde değerlendirilmesi ve tedavi edilmesinde kritik bir öneme sahiptir. Bu derleme ile önemli bir halk sağlığı problemi olan CO zehirlenmesi vakalarında uygulanabilecek oksijen tedavileri konusunda bilgi vermek ve HBO tedavisi için hasta seçiminde kullanılabilecek kriterleri belirlemek amaçlanmıştır

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Cite This Article

METİN, S., YILDIZ, Ş., ÇAKMAK, T. (2011). [The Role of Oxygen Therapies in Carbon Monoxide Poisoning]. TSK Koruyucu Hekimlik Bülteni, Cilt: 10 - Sayı: 4, 487–494. https://ajindex.com/articles/133107

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References (1)

  1. 1 Hampson NB, Weaver LK. Carbon monoxide poisoning: a new incidence for an old disease. Undersea Hyperb Med. 2007; 34(3): 163-168. 2 Thom SR. Carbon monoxide pathophysiology and treatment. Eds.: Neuman TS, Thom SR. Physiology and medicine of hyperbaric oxygen therapy. 1st edition. Philadelphia: Saunders Elsevier, 2008, p. 321-347. 3 Brown SD, Piantadosi CA. In vivo binding of carbon monoxide to cytochrome c oxidase in rat brain. J Appl Physiol. 1990; 68(2): 604-610. 4 Omaye ST. Metabolic modulation of carbon monoxide toxicity. Toxicology. 2002; 180(2): 139- 150. 5 Zhang P, Piantadosi CA. Mitochondrial oxidative stres after carbon monoxide hypoxia in the rat brain. J. Clin. Invest. 1992; 90: 1193-1199. 6 Piantadosi CA, Zhang J, Demchenko IT. Production of hydroxyl radical in the hippocampus after CO hypoxia or hypoxic hypoxia in the rat. Free Radic Biol Med. 1997; 22(4): 725-732. 7 Thom SR, Ischiropoulos H. Mechanism of oxidative stress from low levels of carbon monoxide. Res Rep Health Eff Inst. 1997; (80): 1- 19; discussion 21-27. 8 Thom SR, Fisher D, Xu YA, Garner S, Ischiropoulos H. Role of nitric oxide-derived oxidants in vascular injury from carbon monoxide in the rat. Am J Physiol. 1999; 276: H984-992. 9 Thom SR. Dehydrogenase conversion to oxidase and lipid peroxidation in brain after CO poisoning. J. Appl. Physiol. 1992; 73(4): 1584-1589. 10 Thom SR, Bhopale VM, Fisher D, Zhang J, Gimotty P. Delayed neuropathology after carbon monoxide poisoning is immune-mediated. Proc Natl Acad Sci U S A. 2004; 101(37):13660- 13665. 11 Cobb N, Etzel RA. Unintentional carbon monoxide-related deaths in the United States, 1979 through 1988. JAMA. 1991; 266(5): 659- 663. 12 Centers for Disease Control and Prevention (CDC). Carbon monoxide--related deaths--United States, 1999-2004. MMWR Morb Mortal Wkly Rep. 2007; 56(50): 1309-1312. 13 McDowell R, Fowles J, Phillips D. Deaths from poisoning in New Zealand: 2001-2002. The New Zealand Medical Journal. 2005; 118(1225): U1725. 14 Song KJ, Shin SD, Cone DC. Socioeconomic status and severity-based incidence of poisoning: a nationwide cohort study. Clinical toxicology (Philadelphia, Pa.). 2009; 47(8): 818-826. 15 Salameh S, Amitai Y, Antopolsky M, Rott D, Stalnicowicz R. Carbon monoxide poisoning in Jerusalem: epidemiology and risk factors. Clinical Toxicology (Philadelphia, Pa.). 2009; 47(2): 137- 141. 16 Liu Q, Zhou L, Zheng N, Zhuo L, Liu Y, Liu L. Poisoning deaths in China: type and prevalence detected at the Tongji Fore