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Journals / The European Research Journal / 2026 / Volume: 10 Issue: 1

The relationship between heart functions and anemia in patients with end-stage renal disease receiving hemodialysis

Timor Omar(Department of Cardiology, Kafkas University, Faculty of Medicine, Kars, Turkey)0000-0002-2481-0505
Metin Çağdaş(Department of Cardiology, Kocaeli City Hospital, Kocaeli, Turkey)0000-0001-6704-9886
İnanç Artaç(Department of Cardiology, Kafkas University, Faculty of Medicine, Kars, Turkey)0000-0003-2694-8978
Muammer Karakayalı(Department of Cardiology, Kafkas University, Faculty of Medicine, Kars, Turkey)0000-0001-7385-120X
Doğan İliş(Department of Cardiology, Kafkas University, Faculty of Medicine, Kars, Turkey)0000-0002-1871-5157
Ayça Arslan(Department of Cardiology, Kafkas University, Faculty of Medicine, Kars, Turkey)0000-0002-9152-1199
Yavuz Karabağ(Department of Cardiology, Kafkas University, Faculty of Medicine, Kars, Turkey)0000-0002-8156-315X
Mahmut Yesin(Department of Cardiology, VM Medical Park Kocaeli Hospital, Kocaeli, Turkey)0000-0002-2515-1265
Mustafa Avcı(Department of Internal Medicine, Balikesir Kepsut State Hospital, Balıkesir, Turkey)0000-0002-0522-3284
İbrahim Rencüzoğulları(Department of Cardiology, Kafkas University, Faculty of Medicine, Kars, Turkey)0000-0002-0070-9197
Pages
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Publication Date
2024-01-04
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Our study confirmed impaired cardiac mechanics in ESRD hemodialysis patients and showed that anemia was associated with further worsening cardiac mechanics in this population.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: We investigated the relationship between anemia and cardiac functions by conventional and speckle-tracking echocardiography (STE) in patients with end-stage renal disease (ESRD) receiving hemodialysis.
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Key Findings & Data:In addition, a comparison of the findings between the ESRD patients and healthy controls consisting of 68 participants was conducted.
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Conclusion & Impact:Conclusion: Our study confirmed impaired cardiac mechanics in ESRD hemodialysis patients and showed that anemia was associated with further worsening cardiac mechanics in this population.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Echocardiography · end-stage renal disease · hemodialysis

Abstract

Objective: We investigated the relationship between anemia and cardiac functions by conventional and speckle-tracking echocardiography (STE) in patients with end-stage renal disease (ESRD) receiving hemodialysis. Methods: One hundred six patients with ESRD receiving hemodialysis were included in this cross-sectional study. The conventional echocardiography and STE findings were compared between the patients with and without anemia. In addition, a comparison of the findings between the ESRD patients and healthy controls consisting of 68 participants was conducted. Results: Compared to healthy controls, ESRD patients had lower left ventricular ejection fraction (LVEF), left ventricular global longitudinal strain (LVGLS), and left atrial reservoir strain (LASr) [53% (48-57) vs. 65% (62-68), -15.2 (-16.9˗ -13.6) vs. -19.7 (-16.9˗ -13.6), and -21.9 (-29.5˗ -15.3) vs. -29.9 (-35.3˗ -22.8), respectively, P-value <0.001 for all]. Of the ESRD patients, 70 (66%) had anemia. ESRD patients with anemia had higher interventricular septum (IVS), posterior wall (PW), and left atrial volume index (LAVi) values than patients without anemia. In addition, ESRD patients with anemia had lower LVEF, LVGLS, and LASr than patients without anemia [median (IQR), 13 (12-15) vs. 12 (11-14), P=0.004, 13 (12-15) vs. 12 (11-13.5), P<0.005, 43 (35-55) vs. 34.7 (28-50), P=0.013, 52 (48-55) vs. 56 (47.5-60), P=0.016, -14.6 (-16.4˗ -13.5) vs. -16 (-18.6˗ -14.7), P=0.003, and -21.6 (-30.5˗ -16.3) vs. -30.5 (-33.6˗ -23.3), P=0.006, respectively]. In multivariable logistic regression analysis, diabetes, PW, LASr, and LVGLS were independently associated with the presence of anemia in ESRD patients. Conclusion: Our study confirmed impaired cardiac mechanics in ESRD hemodialysis patients and showed that anemia was associated with further worsening cardiac mechanics in this population.

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Cite This Article

Omar, T., Çağdaş, M., Artaç, İ., Karakayalı, M., İliş, D., Arslan, A., Karabağ, Y., Yesin, M., Avcı, M., Rencüzoğulları, İ. (2024). The relationship between heart functions and anemia in patients with end-stage renal disease receiving hemodialysis. The European Research Journal, Volume: 10 Issue: 1. https://doi.org/10.18621/eurj.1401607

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