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Journals / The European Research Journal / 2026 / Volume: 11 Issue: 2

Cognitive dysfunction after ischemic stroke

Derya Ozdogru(Department of Neurology, Adana City Training and Research Hospital, University of Health Sciences, Adana, Türkiye)0000-0003-3567-1317
Miray Erdem(Department of Neurology, Adana City Training and Research Hospital, University of Health Sciences, Adana, Türkiye)0000-0001-8369-7816
Pages
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Publication Date
2025-03-04
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Conclusions: It should be kept in mind that the MOCA scale can be a good evaluation scale in detecting patients with cognitive impairment after ischemic stroke.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: One of the most important and common consequences of ischemic stroke is the cognitive impairment observed after stroke.
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Key Findings & Data:This study aimed to investigate the role of strategic stroke among post-stroke cognitive impairment using the Montreal Cognitive Assessment Scale (MOCA).
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Conclusion & Impact:Conclusions: It should be kept in mind that the MOCA scale can be a good evaluation scale in detecting patients with cognitive impairment after ischemic stroke.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Montreal Cognitive Assessment Scale · Ischemic stroke · hyperlipidemia

Abstract

Objectives: One of the most important and common consequences of ischemic stroke is the cognitive impairment observed after stroke. This study aimed to investigate the role of strategic stroke among post-stroke cognitive impairment using the Montreal Cognitive Assessment Scale (MOCA). Methods: This study was planned as a prospective cross-sectional study. Patients admitted between 3 and 12 months after stroke were included in the study. Patients who had a stroke at least 3 months ago, who had not been admitted for a year after the stroke, and who gave consent to participate in the study were considered as inclusion criteria. Results: This study included 45 (44.1%) females and 57 (55.9%) males. When evaluated in terms of comorbidity, the frequency of hyperlipidemia was found to be significantly higher in the cognitively impaired group (46.5% vs. 25.4%, P=0.027). Thyroid stimulating hormone (TSH) levels were found to be lower in the Cognitive Impairment Group (0.93 μIU/mL vs. 1.03 μIU/mL, P=0.021). Considering the finding rates and significance level of lesion sites between the groups, the strategic infarction rate was found to be significantly higher in the cognitively impaired group (62.8% vs. 33.9%, P=0.004). In cognitive tests, the cognitive impairment group showed significantly lower performance in all areas (P<0.05). Conclusions: It should be kept in mind that the MOCA scale can be a good evaluation scale in detecting patients with cognitive impairment after ischemic stroke.

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Cite This Article

Ozdogru, D., Erdem, M. (2025). Cognitive dysfunction after ischemic stroke. The European Research Journal, Volume: 11 Issue: 2. https://doi.org/10.18621/eurj.1618895

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References (19)

  1. Pollock A, St George B, Fenton M, Firkins L. Top ten research priorities relating to life after stroke. Lancet Neurol. 2012;11(3):209. doi: 10.1016/S1474-4422(12)70029-7.
  2. Pendlebury ST, Rothwell PM; Oxford Vascular Study. Incidence and prevalence of dementia associated with transient ischaemic attack and stroke: analysis of the population-based Oxford Vascular Study. Lancet Neurol. 2019;18(3):248-258. doi: 10.1016/S1474-4422(18)30442-3.
  3. Barbay M, Taillia H, Nédélec-Ciceri C, et al. Prevalence of Poststroke Neurocognitive Disorders Using National Institute of Neurological Disorders and Stroke-Canadian Stroke Network, VASCOG Criteria (Vascular Behavioral and Cognitive Disorders), and Optimized Criteria of Cognitive Deficit. Stroke. 2018;49(5):1141-1147. doi: 10.1161/STROKEAHA.117.018889.
  4. Pendlebury ST, Rothwell PM. Prevalence, incidence, and factors associated with pre-stroke and post-stroke dementia: a systematic review and meta-analysis. Lancet Neurol. 2009;8(11):1006-1018. doi: 10.1016/S1474-4422(09)70236-4.
  5. Rost NS, Brodtmann A, Pase MP, et al. Post-Stroke Cognitive Impairment and Dementia. Circ Res. 2022;130(8):1252-1271. doi: 10.1161/CIRCRESAHA.122.319951.
  6. Aam S, Einstad MS, Munthe-Kaas R, et al. Post-stroke Cognitive Impairment-Impact of Follow-Up Time and Stroke Subtype on Severity and Cognitive Profile: The Nor-COAST Study. Front Neurol. 2020;11:699. doi: 10.3389/fneur.2020.00699.
  7. Biesbroek JM, Weaver NA, Biessels GJ. Lesion location and cognitive impact of cerebral small vessel disease. Clin Sci (Lond). 2017;131(8):715-728. doi: 10.1042/CS20160452.
  8. Karnath HO, Rennig J. Investigating structure and function in the healthy human brain: validity of acute versus chronic lesion-symptom mapping. Brain Struct Funct. 2017;222(5):2059-2070. doi: 10.1007/s00429-016-1325-7.
  9. Barbay M, Taillia H, Nédélec-Ciceri C, et al. Prevalence of Poststroke Neurocognitive Disorders Using National Institute of Neurological Disorders and Stroke-Canadian Stroke Network, VASCOG Criteria (Vascular Behavioral and Cognitive Disorders), and Optimized Criteria of Cognitive Deficit. Stroke. 2018;49(5):1141-1147. doi: 10.1161/STROKEAHA.117.018889.
  10. Munsch F, Sagnier S, Asselineau J, et al. Stroke Location Is an Independent Predictor of Cognitive Outcome. Stroke. 2016;47(1):66-73. doi: 10.1161/STROKEAHA.115.011242.
  11. Weaver NA, Kuijf HJ, Aben HP, et al. Strategic infarct locations for post-stroke cognitive impairment: a pooled analysis of individual patient data from 12 acute ischaemic stroke cohorts. Lancet Neurol. 2021;20(6):448-459. doi: 10.1016/S1474-4422(21)00060-0.
  12. Weaver NA, Zhao L, Biesbroek JM, et al. The Meta VCI Map consortium for meta-analyses on strategic lesion locations for vascular cognitive impairment using lesion-symptom mapping: Design and multicenter pilot study. Alzheimers Dement (Amst). 2019;11:310-326. doi: 10.1016/j.dadm.2019.02.007.
  13. Karnath HO, Sperber C, Rorden C. Mapping human brain lesions and their functional consequences. Neuroimage. 2018;165:180-189. doi: 10.1016/j.neuroimage.2017.10.028.
  14. Howard VJ, Cushman M, Pulley L, et al. The reasons for geographic and racial differences in stroke study: objectives and design. Neuroepidemiology. 2005;25(3):135-143. doi: 10.1159/000086678.
  15. Jayaraj RL, Azimullah S, Beiram R, Jalal FY, Rosenberg GA. Neuroinflammation: friend and foe for ischemic stroke. J Neuroinflammation. 2019;16(1):142. doi: 10.1186/s12974-019-1516-2.
  16. Rodondi N, den Elzen WP, Bauer DC, et al. Subclinical hypothyroidism and the risk of coronary heart disease and mortality. JAMA. 2010;304(12):1365-1374. doi: 10.1001/jama.2010.1361.
  17. Collet TH, Gussekloo J, Bauer DC, et al. Subclinical hyperthyroidism and the risk of coronary heart disease and mortality. Arch Intern Med. 2012;172(10):799-809. doi: 10.1001/archinternmed.2012.402.
  18. Feigin VL, Forouzanfar MH, Krishnamurthi R, et al. Global and regional burden of stroke during 1990-2010: findings from the Global Burden of Disease Study 2010. Lancet. 2014;383(9913):245-254. doi: 10.1016/s0140-6736(13)61953-4.
  19. Selmer C, Olesen JB, Hansen ML, et al. The spectrum of thyroid disease and risk of new onset atrial fibrillation: a large population cohort study. BMJ. 2012;345:e7895. doi: 10.1136/bmj.e7895.