Journals / The Turkish Journal of Ear Nose and Throat / 2026 / Volume: 22 Issue: 3

Sinonasal extranodal natural killer/T-cell lymphoma: a case report and review of recent developments in the management

Sinonazal ekstranodal doğal katil/T-hücreli lenfoma: Olgu sunumu ve tedavideki son gelişmelerin gözden geçirilmesi

Rabia Nergiz Dağoğlu(İstanbul Üniversitesi İstanbul Tıp Fakültesi Radyasyon Onkolojisi Anabilim Dalı, İstanbul, Türkiye)
Öner Özdemir(İstanbul Medeniyet Üniversitesi Göztepe Eğitim ve Araştırma Hastanesi, 3. Çocuk Sağlığı ve Hastalıkları Kliniği, İmmünoloji-Alerji Bölümü, İstanbul, Türkiye)
Arzu Ergen(İstanbul Üniversitesi İstanbul Tıp Fakültesi Radyasyon Onkolojisi Anabilim Dalı, İstanbul, Türkiye)
Fulya Yaman Ağoğlu(İstanbul Üniversitesi İstanbul Tıp Fakültesi Radyasyon Onkolojisi Anabilim Dalı, İstanbul, Türkiye)
Pages
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Publication Date
2012-07-22
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The management of the disease was reviewed in the light of the recent literature data.

📌 3 Key Takeaways

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Objective & Hypothesis:Nasal extranodal natural killer/T-cell lymphoma, which is a highly aggressive disease, is more frequently seen in Asia than in Western countries.
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Key Findings & Data:In this article, we present a 52-year-old male patient with early recurrence and who was refractory to chemotherapy.
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Conclusion & Impact:The management of the disease was reviewed in the light of the recent literature data.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Chemotherapy · lethal midline granuloma · lymphomatoid granuloma

Abstract

Nasal extranodal natural killer/T-cell lymphoma, which is a highly aggressive disease, is more frequently seen in Asia than in Western countries. No consensus has been reached on the management of the disease and the survival depends on the stage of the disease. Localized NK/T-cell lymphoma often responds to radiotherapy well. However, patients with advanced disease or recurrence after chemoradiotherapy, similar to our patient, have a very poor prognosis. In this article, we present a 52-year-old male patient with early recurrence and who was refractory to chemotherapy. The management of the disease was reviewed in the light of the recent literature data.

Özet

Nazal ekstranodal doğal katil NK /T-hücreli lenfo- ma çok agresif bir hastalık olup, Asya’da Batı ülke- lerine göre daha sık görülen bir hastalıktır. Standart tedavi üzerine bir uzlaşma mevcut olmamakla bir- likte, sağkalım hastalığın evresine bağlıdır. Lokalize NK/T-hücreli lenfoma, radyoterapiye genellikle iyi yanıt verir. Hastamız gibi ilerlemiş hastalığı olan veya kemoradyoterapiden sonra hastalığı nüks edenler, çok kötü bir prognoza sahiptir. Bu yazıda, hastalığı erken nüks eden ve kemoradyoterapiye dirençli olan 52 yaşında bir erkek hasta sunuldu. Hastalığın tedavisi yeni literatür verileri ışığında gözden geçirildi

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Cite This Article

Dağoğlu, R. N., Özdemir, Ö., Ergen, A., Ağoğlu, F. Y. (2012). Sinonasal extranodal natural killer/T-cell lymphoma: a case report and review of recent developments in the management. The Turkish Journal of Ear Nose and Throat, Volume: 22 Issue: 3. https://ajindex.com/articles/1329711

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