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Journals / The Turkish Journal of Ear Nose and Throat / 2026 / Volume: 34 Issue: 1

Clinical Outcomes of Supraglottic Laryngeal Cancer: Insights from a Decade of Surgical Treatment

Yaşar Kemal Duymaz(University of Health Sciences, Ümraniye Training and Research Hospital, Department of Otolaryngology)0000-0002-4887-4677
Pages
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Publication Date
2024-03-27
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The 5-year overall survival rate was 72.2%, with a recurrence rate of 7.1%.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: This study sought to retrospectively examine the clinical outcomes of patients treated for supraglottic laryngeal cancer at a single center over a decade, assess the efficacy of surgical interventions, and evaluate survival rates in comparison to current literature.
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Key Findings & Data:Materials and Methods: A retrospective analysis was conducted on 84 patients diagnosed with supraglottic laryngeal cancer who underwent surgical treatment between January 2008 and December 2018.
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Conclusion & Impact:The 5-year overall survival rate was 72.2%, with a recurrence rate of 7.1%.
🔬Design:Research Article
📍Scope:2008 Verileri
⚙️Variables:Supraglottic laryngeal cancer · squamous cell carcinoma · neck dissection

Abstract

Objective: This study sought to retrospectively examine the clinical outcomes of patients treated for supraglottic laryngeal cancer at a single center over a decade, assess the efficacy of surgical interventions, and evaluate survival rates in comparison to current literature. Materials and Methods: A retrospective analysis was conducted on 84 patients diagnosed with supraglottic laryngeal cancer who underwent surgical treatment between January 2008 and December 2018. Nonlaryngeal head and neck malignancies and inaccessible patient records were excluded. The study evaluated factors including tumor location, tumor stage, lymph node metastasis, surgical approach, complications, histopathological findings, and adjuvant therapy. Statistical analysis involved descriptive methods, frequencies, and ratios, with outcomes compared to existing literature. Results: The cohort primarily consisted of male patients (91.7%) with an average age of 58.04 years. Squamous cell carcinoma was the predominant histopathological type (98.8%), exhibiting various degrees of differentiation. Most patients presented with advanced-stage disease (III or IV), with 53.6% undergoing total laryngectomy. Neck dissection was performed in 95.2% of cases, and 69% received postoperative radiotherapy. The 5-year overall survival rate was 72.2%, with a recurrence rate of 7.1%. Conclusion: This study reveals that supraglottic laryngeal cancer, predominantly affecting older males, is frequently diagnosed at advanced stages. Surgical intervention resulted in a 5-year survival rate consistent with existing literature. Despite the limitation of its retrospective design and the small, single-center sample, the findings support current treatment modalities while underscoring the importance of early detection and further research.

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Cite This Article

Duymaz, Y. K. (2024). Clinical Outcomes of Supraglottic Laryngeal Cancer: Insights from a Decade of Surgical Treatment. The Turkish Journal of Ear Nose and Throat, Volume: 34 Issue: 1. https://doi.org/10.26650/Tr-ENT.2024.1387086

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