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Journals / Turkish Journal of Clinics and Laboratory / 2026 / Cilt: 15 Sayı: 3

The diagnostic value of systemic inflammation indices in pregnant women with acute appendicitis and their relationship with the duration of hospital stay

Gebe kadınlarda akut apandisitli hastalarda sistemik inflamasyon indekslerinin tanısal değeri ve hastanede kalış süresi ile korelasyonu

Bercis İmge Uçar(KÜTAHYA SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, TIP FAKÜLTESİ, CERRAHİ TIP BİLİMLERİ BÖLÜMÜ)0000-0003-0229-5589
Muhammed Alperen Taş(KUTAHYA HEALTH SCIENCES UNIVERSITY)0000-0002-4060-121X
Pages
494–500
Publication Date
2024-09-30
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

SII demonstrated superior accuracy over NLR and PLR, correlating with both the Alvarado score and hospital stay, suggesting its utility as a diagnostic and prognostic marker.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Physiological and anatomical changes occurring during pregnancy can complicate the diagnosis of acute appendicitis (AA).
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Key Findings & Data:This study aimed to evaluate the diagnostic performance of systemic inflammation indices in distinguishing AA in pregnant women and to assess their relationship with hospital stay duration.
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Conclusion & Impact:SII demonstrated superior accuracy over NLR and PLR, correlating with both the Alvarado score and hospital stay, suggesting its utility as a diagnostic and prognostic marker.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:akut apandisit · Alvarado skoru · gebelik

Abstract

Aim: Physiological and anatomical changes occurring during pregnancy can complicate the diagnosis of acute appendicitis (AA). This study aimed to evaluate the diagnostic performance of systemic inflammation indices in distinguishing AA in pregnant women and to assess their relationship with hospital stay duration. Material and Methods: This retrospective study encompassed 32 pregnant patients who underwent appendectomy and 32 healthy pregnant (control group). Systemic inflammation indices were calculated based on neutrophil (N), platelet (P), and lymphocyte (L) levels as follows: The neutrophil-to-lymphocyte ratio (NLR) = N/L; the platelet-to-lymphocyte ratio (PLR) = P/L; systemic immune-inflammation index (SII) = (N×P)/L. Results: The AA group had higher median levels of PLR (30.9 vs. 22.4, p = 0.035), NLR (6.1 vs. 3.5, p 1316, with a sensitivity of 85.8% and a specificity of 72.5%. Conclusions: Systemic inflammation indices, particularly SII, demonstrate strong diagnostic value in distinguishing AA in pregnant women. SII demonstrated superior accuracy over NLR and PLR, correlating with both the Alvarado score and hospital stay, suggesting its utility as a diagnostic and prognostic marker.

Özet

Amaç: Gebelik sırasında meydana gelen fizyolojik ve anatomik değişiklikler, akut apandisit (AA) tanısını zorlaştırabilir. Bu çalışmada gebe kadınlarda AA'yı ayırt etmede sistemik inflamasyon indekslerinin tanısal performansının değerlendirilmesi ve hastanede kalış süresi ile ilişkisinin değerlendirilmesi amaçlandı. Gereç ve Yöntemler: Bu retrospektif çalışma, apendektomi uygulanan 32 gebe hasta ile 32 sağlıklı gebe (kontrol grubu) üzerinde gerçekleştirilmiştir. Sistemik inflamasyon indeksleri, nötrofil (N), trombosit (P) ve lenfosit (L) düzeylerine göre şu şekilde hesaplanmıştır: nötrofil-lenfosit oranı (NLR) = N/L; trombosit-lenfosit oranı (PLR) = P/L; sistemik immün-inflamasyon indeksi (SII) = (N×P)/L. Bulgular: AA grubunda kontrol grubuna kıyasla PLR (30.9 vs. 22.4, p = 0.035), NLR (6.1 vs. 3.5, p 1316 olup, duyarlılık %85.8 ve özgüllük %72.5 olarak belirlenmiştir. Sonuç: Sistemik inflamasyon indeksleri, özellikle SII, gebelerde AA'yı ayırt etmede güçlü tanısal bir değere sahiptir. SII'nin hem Alvarado skoru hem de hastanede kalış süresi ile korelasyon göstererek NLR ve PLR'ye göre üstün doğruluk gösterdiği ve tanı ve prognoz belirteci olarak yararlı olduğunu düşündürmektedir.

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Cite This Article

Uçar, B. İ., Taş, M. A. (2024). The diagnostic value of systemic inflammation indices in pregnant women with acute appendicitis and their relationship with the duration of hospital stay. Turkish Journal of Clinics and Laboratory, Cilt: 15 Sayı: 3, 494–500. https://doi.org/10.18663/tjcl.1445438

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