SavedAdd your journal

Journals / Türk Doğa ve Fen Dergisi / 2026 / Cilt: 15 Sayı: 3

Determination of Some Important Properties of Lavandula Stoechas (Lavender) Plant for Human Health

Lavandula stoechas (Karabaş Otu) Bitkisinin İnsan Sağlığı İçin Önemli Bazı Özelliklerinin Belirlenmesi

Mustafa Yunus Emre(MARDİN ARTUKLU ÜNİVERSİTESİ)0000-0001-6602-8872
Muhammed Güngören(MARDİN ARTUKLU ÜNİVERSİTESİ, SAĞLIK HİZMETLERİ MESLEK YÜKSEKOKULU)0000-0002-3122-7086
Pages
221–230
Publication Date
2026-09-30
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The antimicrobial effect of L. stoechas on Escherichia coli, Staphylococcus aureus, and Candida albicans strains was investigated, and it was found to have an antimicrobial effect only on Staphylococcus aureus.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Medicinal plants, used in the treatment of many diseases, are natural sources of healing.
📊
Key Findings & Data:In Turkey, the use of this plant for medicinal purposes such as analgesic, antiseptic, wound healing, sedative, expectorant, urinary tract infection relief, eczema wound healing, and strengthening nerves and the heart is widespread.
💡
Conclusion & Impact:The antimicrobial effect of L. stoechas on Escherichia coli, Staphylococcus aureus, and Candida albicans strains was investigated, and it was found to have an antimicrobial effect only on Staphylococcus aureus.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Lavandula stoechas · Rosmanirik asit · Staphylococcus aureus

Abstract

Medicinal plants, used in the treatment of many diseases, are natural sources of healing. Due to the phenolic compounds they contain, such as flavonoids, phenylpropanoids, and stilbenes, medicinal plants are used in the treatment of various diseases. In Turkey, the use of this plant for medicinal purposes such as analgesic, antiseptic, wound healing, sedative, expectorant, urinary tract infection relief, eczema wound healing, and strengthening nerves and the heart is widespread. Because of these effects, in this study we examined certain properties of the extracts of Lavandula stoechas, grown in our country, in different solvents that are important for human health. The DPPH scavenging capacity of the methanol extract of L. stoechas was calculated as 56.345 ± 0.360 µg/Ml trolox equivalent, and the TPC value was calculated as 55.356 ± 1.806 mg/g gallic acid equivalent. When we examined the volatile components, the compound groups with the highest amounts were identified as trans-Verbenol in alcohols, α-Campholenal in aldehydes, (-)-Camphor in ketones, Bornyl acetate in esters, and Camphene in terpenes. In our study, the phenolic components catechin, caffeic acid, vanillic acid, p-coumaric acid, gallic acid, and rosmarinic acid were investigated, and rosmarinic acid was the compound detected in the highest amount among both extract results. The antimicrobial effect of L. stoechas on Escherichia coli, Staphylococcus aureus, and Candida albicans strains was investigated, and it was found to have an antimicrobial effect only on Staphylococcus aureus.

Özet

Birçok hastalığın tedavisinde kullanılan tıbbi bitkiler doğal tedavi kaynaklarıdır. Tıbbi bitkiler içeriğinde yer alan flavonoidler, fenilpropanoidler, stilbenler gibi fenolik maddelerden dolayı farklı hastalıkların tedavisinde kullanılırlar. Bu bitkinin ağrı kesici, antiseptik, yara iyileştirici, yatıştırıcı, balgam söktürücü, idrar yolu iltihabını giderici, egzama yaralarını iyileştirici, sinir ve kalbi güçlendirici gibi tıbbi amaçlarla kullanımı Türkiye’de yaygındır. Bu etkilerinden dolayı bu çalışmada bizde ülkemizde yetişen L. stoechas bitkisinin farklı çözücülerdeki ekstraklarının insan sağlığı açısından önemli bazı özelliklerini inceledik. L. stoechas bitkisinin metanollu ekstraktının DPPH giderme kapasitesi 56.345 0.360 µg/Ml trolox eş değeri olarak, TPC değeri ise 55.356 ± 1.806 mg/g gallik asit eşdeğeri olarak hesaplanmıştır. Uçucu bileşenlerini incelediğimizde en fazla miktara sahip bileşik grupları alkolerde trans-Verbenol, aldehitlerde α-Campholenal, ketonlarda (-)-Camphor, esterlerde Bornyl acetate ve terpenlerde Camphene olarak tespit edilmiştir. Çalışmamızda kateşin, kafeik asit, vanilik asit, p-kumarik asit, gallik asit ve rosmanirik asit fenolik bileşenleri çalışılmış olup her iki ekstraklı sonuçlar içerisinde rosmanirik asit en yüksek miktarda tespit edilen bileşik olmuştur. L. stoechas bitkisinin Escherichia coli, Staphylococcus aureus ve Candida albicans suşları üzerine antimikrobiyal etkisi incelenmiş sadece Staphylococcus aureus üzerine antimikrobiyal etki gösterdiği tespit edilmiştir.

🔖

Cite This Article

Emre, M. Y., Güngören, M. (2026). Determination of Some Important Properties of Lavandula Stoechas (Lavender) Plant for Human Health. Türk Doğa ve Fen Dergisi, Cilt: 15 Sayı: 3, 221–230. https://doi.org/10.46810/tdfd.1901086

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (54)

  1. Dhayalan, M., Jegadeeshwari, L. A., & Gandhi, N. N. (2015). Biological activity sources from traditionally used tribe and herbal plants material. Asian J Pharm Clin Res, 8(6), 11-23.
  2. Alok Krishna, A. K., Rakesh Tiwari, R. T., & Sushil Kumar, S. K. (2000). Aromatherapy-an alternative health care through essential oils.
  3. World Health Organization. WHO global report on traditional, complementary and integrative medicine 2024. Geneva: World Health Organization; 2025. Available from: https://www.who.int/publications/b/78436
  4. Pan, S., Neeraj, A., Srivastava, K. S., Kishore, P., Danquah, M. K., & Sarethy, I. P. (2013). A proposal for a quality system for herbal products. Journal of Pharmaceutical Sciences, 102(12), 4230-4241.
  5. Maghrabi, W. H., Badr, H., Alkhyat, A., Schlaeger, J. M., & Cynthia, F. (2025). Perceived usefulness drives the use of traditional, complementary, and integrative medicine: a systematic umbrella review. Journal of Integrative and Complementary Medicine, 31(9), 768-779.
  6. Tillisch, K. (2007). Complementary and alternative medicine for gastrointestinal disorders. Clinical medicine, 7(3), 224-227.
  7. Chaachouay, N., & Zidane, L. (2024). Plant-derived natural products: a source for drug discovery and development. Drugs and Drug Candidates, 3(1), 184-207.
  8. Singh, M. P., & Gohil, K. J. (2024). Therapeuticefficacy andcost effectiveness ofherbal drugs–A reasonable approach. Pharmacological Research-Natural Products, 2, 100009.
  9. Singab, A.N.B., El-Beshbishy, H.A., Yonekawa, M., Nomura, T., & Fukai, T. (2005). Hypoglycemic effect of Egyptian Morus alba root bark extract: effect on diabetes and lipid peroxidation of streptozotocin-induced diabetic rats. Journal of Ethnopharmacology, 100(3), 333-338.
  10. Bhandari, M.R., Jong-Anurakkun, N., Hong, G., & Kawabata, J. (2008). α-Glucosidase and α-amylase inhibitory activities of Nepalese medicinal herb Pakhanbhed (Bergenia ciliata, Haw.). Food Chemistry, 106(1), 247-252.
  11. Kähkönen, M. P., Hopia, A. I., Vuorela, H. J., Rauha, J. P., Pihlaja, K., Kujala, T. S., & Heinonen, M. (1999). Antioxidant activity of plant extracts containing phenolic compounds. Journal of agricultural and food chemistry, 47(10), 3954-3962.
  12. Alfadda, A. A., & Sallam, R. M. (2012). Reactive oxygen species in health and disease. BioMed research international, 2012(1), 936486.
  13. Khan, I., Ahmad, S., Khan, I. (2016). Ustukhuddoos (Lavandula stoechas Linn.)-A Review on Morphology, Phytochemistry and Pharmacological Activities. Journal of The Internatıonal Socıety For The Hıstory Of Islamıc Medıcıne (JISHIM), 14,15, 52.
  14. Vilas-Boas, A. A., Goméz-García, R., Machado, M., Nunes, C., Ribeiro, S., Nunes, J.,. & Pintado, M. (2023). Lavandula pedunculata polyphenol-rich extracts obtained by conventional, MAE and UAE methods: Exploring the bioactive potential and safety for use a medicine plant as food and nutraceutical ingredient. Foods, 12(24), 4462.
  15. Ez zoubi, Y., Bousta, D., & Farah, A. (2020). A Phytopharmacological review of a Mediterranean plant: Lavandula stoechas L. Clinical Phytoscience, 6(1), 9. https://doi.org/10.1186/s40816-019-0142-y
  16. Hedayati, S., Tarahi, M., Madani, A., Mazloomi, S. M., & Hashempur, M. H. (2025). Towards a greener future: Sustainable innovations in the extraction of lavender (Lavandula spp.) essential oil. Foods, 14(1), 100.
  17. Ahamad, R., Kumar, S., Akhtar, M., Aqil, M., Yar, M. S., Akram, M.,. & Mujeeb, M. (2025). A Comprehensive Review of Lavandula stoechas L.(Ustukhuddus) Plant: Phytochemistry, Pharmacology, and In Silico Studies. Chemistry & Biodiversity, 22(4), e202401996
  18. Benabdelkader, T., Zitouni, A., Guitton, Y., Jullien, F., Maitre, D., Casabianca, H.,. & Kameli, A. (2011). Essential oils from wild populations of Algerian Lavandula stoechas L.: composition, chemical variability, and in vitro biological properties. Chemistry & biodiversity, 8(5), 937-953.
  19. Oraloğlu, Z. (2018). Bitkisel drog monografı hazırlanması: Lavandula stoechas L. [Preparatı̇on A herbal drog monograph: Lavandula stoechas L.] [Unpublished Master Thesis]. Anadolu University.
  20. Kültür, Ş., Altınbaşak, O., Anıl, S., & Melikoğlu, G. (2018). Türkiye’de mide ülserinde kullanılan tıbbi bitkiler [Medicinal plants used in gastric ulcer in Turkey]. Marmara Pharmaceutical Journal, 22, 1-14. http://doi.org/10.12991/mpj.2018.35
  21. Bozyel, M.E., & Merdamert-Bozyel, E. (2020). Ethnomedicinal Uses of Genus Lavandula (Lamiaceae) in Turkish Traditional Medicine. International Journal of Academic and Applied Research, 4(2), 5-16.
  22. Bozyel, M.E., Merdamert-Bozyel, E., Canli, K., & Altuner, E.M. (2019). Anticancer Uses of Medicinal Plants in Turkish Traditional Medicine. KSÜ Tarım ve Doğa Dergisi, 22(2), 465-484.
  23. Akkoyun, M. B., Akkoyun, T., Ekin, S., Temel, Y., Bakır, A., Bengü, A. Ş., & Özgökçe, F. (2025). Determination of Antioxidant-Antiradical Activity and Vitamin C Content of Peucedanum longifolium Waldst. & Kit. Türk Doğa ve Fen Dergisi, 14(4), 50-57.
  24. Blois, M. S. (1958). Antioxidant determinations by the use of a stable free radical. Nature, 181(4617), 1199-1200. https://doi.org/10.1038/1811199a0
  25. Sánchez-Moreno, C., Larrauri, J. A., & Saura-Calixto, F. (1998). A procedure to measure the antiradical efficiency of polyphenols. Journal of the Science of Food and Agriculture, 76(2), 270–276. https://doi.org/10.1002/(SICI)1097-0010(199802)76:2 3.0.CO;2-9
  26. Genovese, C., Timpanaro, N., Nicolosi, D., & Tempera, G. (2015). Chemical composition of Centaurea extracts. Pharmacognosy Research, 7(3), 281–287. https://doi.org/10.4103/0974-8490.157990
  27. Capanoglu, E., De Vos, R. C., Hall, R. D., Boyacioglu, D., & Beekwilder, J. (2013). Changes in polyphenol content during production of grape juice concentrate. Food Chemistry, 139(1-4), 521526.
  28. Veneziani, R. C. S., Ambrósio, S. R., Martins, C. H. G., Lemes, D. C., & Veneziani, L. F. (2018). Chemical composition, antimicrobial and antioxidant activities of essential oils from Centaurea species. Industrial Crops and Products, 112, 793–801. https://doi.org/10.1016/j.indcrop.2017.12.073
  29. NCCLS. (1997). Performance standards for antimicrobial disk susceptibility tests (6th ed., Approved Standard M2-A6). National Committee for Clinical Laboratory Standards.
  30. Ceylan, Y., Usta, K., Usta, A., Maltas, E., & Yildiz, S. (2015). Evaluation of antioxidant activity, phytochemicals and ESR analysis of Lavandula stoechas. Acta physica polonica A, 128(2B).
  31. Mushtaq, A., Anwar, R., & Ahmad, M. (2018). Lavandula stoechas (L) a very potent antioxidant attenuates dementia in scopolamine induced memory deficit mice. Frontiers in pharmacology, 9, 1375.
  32. Mokhtarzadeh, S., Demirci, B., AĞALAR, H., Khawar, K., & KIRIMER, N. (2019). In vitro propagation and volatile compound characterization of Lavandula stoechas L. subsp. stoechas-an economically important source of essential oil. Records of Natural Products, 13(2).
  33. Sharma, N., Yadav, Y., Kumar, V., & Sharma, K. C. (2021). Folkare and modern pharmacology of camphor (Cinnamomum camphora Nees & Eberm): Review. Sch Int J Tradit Complement Med, 4(7), 128-135.
  34. Chen, N., Sun, G., Yuan, X., Hou, J., Wu, Q., Soromou, L. W., & Feng, H. (2014). Inhibition of lung inflammatory responses by bornyl acetate is correlated with regulation of myeloperoxidase activity. Journal of Surgical Research, 186(1), 436-445.
  35. Wu, J., Ren, J., Wang, L., Yang, Z., Wang, X., Tu, Z.,. & Cao, Y. (2025). The active constituent of pine needle oil, bornyl acetate, suppresses NSCLC progression by inhibiting the PI3K/AKT/ABCB1 signaling axis. Frontiers in Pharmacology, 16, 1653461.
  36. Batiha, G. E. S., Teibo, J. O., Wasef, L., Shaheen, H. M., Akomolafe, A. P., Teibo, T. K. A.,. & Papadakis, M. (2023). A review of the bioactive components and pharmacological properties of Lavandula species. Naunyn-schmiedeberg's Archives of Pharmacology, 396(5), 877-900.
  37. Kowalczyk, A., Tuberoso, C. I. G., & Jerković, I. (2024). The role of Rosmarinic acid in cancer prevention and therapy: mechanisms of antioxidant and anticancer activity. Antioxidants, 13(11), 1313.
  38. Gholami, F., Antonio, J., Iranpour, M., Curtis, J., & Pereira, F. (2024). Does green tea catechin enhance weight-loss effect of exercise training in overweight and obese individuals? a systematic review and meta-analysis of randomized trials. Journal of the International Society of Sports Nutrition, 21(1), 2411029.
  39. Singh, B. N., Shankar, S., & Srivastava, R. K. (2011). Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications. Biochemical pharmacology, 82(12), 1807-1821.
  40. Yang, C. S., Lambert, J. D., & Sang, S. (2009). Antioxidative and anti-carcinogenic activities of tea polyphenols. Archives of toxicology, 83(1), 11-21.
  41. Baranwal, A., Aggarwal, P., Rai, A., & Kumar, N. (2022). Pharmacological actions and underlying mechanisms of catechin: A review. Mini Reviews in Medicinal Chemistry, 22(5), 821-833.
  42. Maity, R., Chatterjee, M., Banerjee, A., Das, A., Mishra, R., Mazumder, S., & Chanda, N. (2019). Gold nanoparticle-assisted enhancement in the anti-cancer properties of theaflavin against human ovarian cancer cells. Materials Science and Engineering: C, 104, 109909.
  43. Kaur, J., Gulati, M., Singh, S. K., Kuppusamy, G., Kapoor, B., Mishra, V.,. & Corrie, L. (2022). Discovering multifaceted role of vanillic acid beyond flavours: Nutraceutical and therapeutic potential. Trends in Food Science & Technology, 122, 187-200.
  44. Shen, Y., Song, X., Li, L., Sun, J., Jaiswal, Y., Huang, J.,. & Guan, Y. (2019). Protective effects of p-coumaric acid against oxidant and hyperlipidemia-an in vitro and in vivo evaluation. Biomedicine & Pharmacotherapy, 111, 579-587.
  45. Hickl, J., Argyropoulou, A., Al-Ahmad, A., Hellwig, E., Skaltsounis, A. L., Wittmer, A.,. & Karygianni, L. (2024). Unleashing nature's defense: potent antimicrobial power of plant extracts against oral pathogens and Streptococcus mutans biofilms. Frontiers in Oral Health, 5, 1469174.
  46. Canlı, K., Yetgin, A., Benek, A., Bozyel, M. E., & Murat Altuner, E. (2019). In vitro antimicrobial activity screening of ethanol extract of Lavandula stoechas and investigation of its biochemical composition. Advances in Pharmacological and Pharmaceutical Sciences, 2019(1), 3201458.
  47. Vilas-Boas, A. A., Goméz-García, R., Machado, M., Nunes, C., Ribeiro, S., Nunes, J.,. & Pintado, M. (2023). Lavandula pedunculata polyphenol-rich extracts obtained by conventional, MAE and UAE methods: Exploring the bioactive potential and safety for use a medicine plant as food and nutraceutical ingredient. Foods, 12(24), 4462.
  48. Ahamad, R., Kumar, S., Akhtar, M., Aqil, M., Yar, M. S., Akram, M.,. & Mujeeb, M. (2025). A Comprehensive Review of Lavandula stoechas L.(Ustukhuddus) Plant: Phytochemistry, Pharmacology, and In Silico Studies. Chemistry & Biodiversity, 22(4), e202401996
  49. Benabdelkader, T., Zitouni, A., Guitton, Y., Jullien, F., Maitre, D., Casabianca, H.,. & Kameli, A. (2011). Essential oils from wild populations of Algerian Lavandula stoechas L.: composition, chemical variability, and in vitro biological properties. Chemistry & biodiversity, 8(5), 937-953.
  50. Wu, J., Ren, J., Wang, L., Yang, Z., Wang, X., Tu, Z.,. & Cao, Y. (2025). The active constituent of pine needle oil, bornyl acetate, suppresses NSCLC progression by inhibiting the PI3K/AKT/ABCB1 signaling axis. Frontiers in Pharmacology, 16, 1653461.
  51. Batiha, G. E. S., Teibo, J. O., Wasef, L., Shaheen, H. M., Akomolafe, A. P., Teibo, T. K. A.,. & Papadakis, M. (2023). A review of the bioactive components and pharmacological properties of Lavandula species. Naunyn-schmiedeberg's Archives of Pharmacology, 396(5), 877-900.
  52. Kaur, J., Gulati, M., Singh, S. K., Kuppusamy, G., Kapoor, B., Mishra, V.,. & Corrie, L. (2022). Discovering multifaceted role of vanillic acid beyond flavours: Nutraceutical and therapeutic potential. Trends in Food Science & Technology, 122, 187-200.
  53. Shen, Y., Song, X., Li, L., Sun, J., Jaiswal, Y., Huang, J.,. & Guan, Y. (2019). Protective effects of p-coumaric acid against oxidant and hyperlipidemia-an in vitro and in vivo evaluation. Biomedicine & Pharmacotherapy, 111, 579-587.
  54. Hickl, J., Argyropoulou, A., Al-Ahmad, A., Hellwig, E., Skaltsounis, A. L., Wittmer, A.,. & Karygianni, L. (2024). Unleashing nature's defense: potent antimicrobial power of plant extracts against oral pathogens and Streptococcus mutans biofilms. Frontiers in Oral Health, 5, 1469174.