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Journals / TSK Koruyucu Hekimlik Bülteni / 2008 / Cilt: 7 - Sayı: 3

İdrar yolu enfeksiyonlarının saptanması için tarama testi: İdrar lökosit esteraz strip testinin değerlendirilmesi

Screening test for detection of urinary tract infections: Evaluation of the urinary leukocyte esterase dipstick test

Mohammed Wael Abu GHOUSH
Pages
187–190
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Also, leukocyte esterase dipstick urine test was considered as a useful screening test that could be used in population based studies.

📌 3 Key Takeaways

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Objective & Hypothesis:AIM/BACKGORUND: To compare the performance of leukocyte esterase dipstick test with microscopic examination in cases with clinically suspected urinary tract infections.
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Key Findings & Data:METHOD: Freshly urine specimens from 504 patients were analyzed for the presence of white blood cells (WBCs) by leukocyte esterase dipstick test and microscopically WBCs/high power field).
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Conclusion & Impact:Also, leukocyte esterase dipstick urine test was considered as a useful screening test that could be used in population based studies.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:İdrar tahlili · İdrar yolu enfeksiyonları · Duyarlılık ve özgüllük

Abstract

AIM/BACKGORUND: To compare the performance of leukocyte esterase dipstick test with microscopic examination in cases with clinically suspected urinary tract infections. METHOD: Freshly urine specimens from 504 patients were analyzed for the presence of white blood cells (WBCs) by leukocyte esterase dipstick test and microscopically WBCs/high power field). A reaction of 1+ or more was taken as a definite indication of significant numbers of leukocytes.Urine dipstick tests were compared with pyuria for each sample. Results were statistically compared. RESULTS: The sensitivity of dipstick leukocyte esterase was found to be 68.5%, whereas the specificity was 73.5%. Microscopic WBCs showed 34% sensitivity with 86.5% specificity. False negative results for leukocyte esterase could occur due to the heavy protienuria, and/or insufficient release of esterase from WBCs. In addition, false negative WBCs count might obtain in case of lyses. CONCLUSION: Leukocyte esterase dipstick urine analysis was considered adequate screening tools in UTI cases. However, caution must be taken in interpreting factors that could affect the results of urine dipstick. Also, leukocyte esterase dipstick urine test was considered as a useful screening test that could be used in population based studies.

Özet

AMAÇ: Klinik olarak idrar yolu enfeksiyonundan şüphelenilen olgularda mikroskobik değerlendirme ile lökosit esteraz strip testinin performansını karşılaştırmak. YÖNTEM: 504 hastadan alınan taze idrar örnekleri lökosit varlığı açısından lökosit esteraz idrar strip testi ile ve mikroskopla (lökosit/büyük saha) incelendi. Lökosit esteraz testinde 1+ veya daha büyük değerler önemli derecede çok lökosit sayısı için kesin gösterge olarak kabul edildi. Her örneğin idrar strip analiz sonuçları piüri sonuçları ile karşılaştırıldı. Sonuçlar istatistiksel olarak değerlendirildi.. BULGULAR: Lökosit esteraz strip testinin hassasiyeti %68,5 olarak hesaplanırken, seçiciliği %73,5 olarak hesaplanmıştır. Mikroskobik lökosit analizinin hassasiyeti %34, seçiciliği %86,5 olarak bulunmuştur. Ağır proteinüri ve/veya lökositlerden yetersiz esteraz salınımı lökosit esteraz sonuçlarının yanlış negatif çıkmasına neden olabilmektedir. Yine parçalanma durumlarında yanlış negatif lökosit sayımı meydana gelebilmektedir. SONUÇ: Lökosit esteraz idrar analizi idrar yolu enfeksiyonlarının tanısı yeterli bir tarama testi olarak değerlendirildi. Bununla birlikte idrar lökosit esteraz analizinde karıştırıcı etkenlere dikkat edilmelidir. Ayrıca, lökosit esteraz idrar testinin toplumsal araştırmalarda kullanılabilecek faydalı bir tarama testi olabileceği değerlendirildi.

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Cite This Article

GHOUSH, M. W. A. (2008). İdrar yolu enfeksiyonlarının saptanması için tarama testi: İdrar lökosit esteraz strip testinin değerlendirilmesi. TSK Koruyucu Hekimlik Bülteni, Cilt: 7 - Sayı: 3, 187–190. https://ajindex.com/articles/131699

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