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Journals / Selcuk Dental Journal / 2026 / Volume: 10 Issue: 4 Special Issue

ORAL AND DENTAL FINDINGS OF A CHILD WITH WEILL-MARCHESANI SYNDROME TYPE II: A CASE REPORT WITH 3-YEAR FOLLOW-UP

Burcu Güçyetmez Topal(AFYONKARAHİSAR SAĞLIK BİLİMLERİ ÜNİVERSİTESİ)0000-0002-9932-9169
Muhsin Elmas(Afyonkarahisar Sağlık Bilimleri Üniversitesi)0000-0002-5626-2160
Melike Tıraş(Afyonkarahisar Sağlık Bilimleri Üniversitesi)0000-0001-7723-1155
Pages
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Publication Date
2023-06-15
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The present case report describes oral and dental findings of a 63 months old female patients with WMS2.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Weill-Marchesani syndrome (WMS, OMIM# 227600) is a genetically determined, rare systemic connective tissue disorder.
📊
Key Findings & Data:Given the limited number of individuals with WMS in the literature, no genotype-phenotype correlations for ADAMTS10, ADAMTS17, FBN1, or LTBP2 have been identified.
💡
Conclusion & Impact:The present case report describes oral and dental findings of a 63 months old female patients with WMS2.
🔬Design:Case Report
📍Scope:Comprehensive Sample
⚙️Variables:Dental Anomalies · FNB-1 gene mutation · Weill-Marchesani Syndrome

Abstract

Weill-Marchesani syndrome (WMS, OMIM# 227600) is a genetically determined, rare systemic connective tissue disorder. The syndrome is divided into four types according to mutations in related genes. Given the limited number of individuals with WMS in the literature, no genotype-phenotype correlations for ADAMTS10, ADAMTS17, FBN1, or LTBP2 have been identified. In the accessible literature, none of the limited studies were focused on the oral and dental anomalies of WMS. The present case report describes oral and dental findings of a 63 months old female patients with WMS2.

Özet

Weill-Marchesani sendromu (WMS, OMIM# 227600) genetik olarak tanımlanmış, nadir görülen bir sistemik bağ dokusu hastalığıdır. Sendrom, ilgili genlerdeki mutasyonlara göre dört tipe ayrılmaktadır. Literatürde WMS'li sınırlı sayıda birey göz önüne alındığında, ADAMTS10, ADAMTS17, FBN1 veya LTBP2 için genotip-fenotip korelasyonu tanımlanmamıştır. Erişilebilir literatürde, sınırlı çalışmaların hiçbiri WMS'nin ağız ve diş anomalilerine odaklanmamıştır. Bu vaka raporu, WMS2'li 63 aylık bir kadın hastanın ağız ve diş bulgularını tanımlamaktadır.

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Cite This Article

Topal, B. G., Elmas, M., Tıraş, M. (2023). ORAL AND DENTAL FINDINGS OF A CHILD WITH WEILL-MARCHESANI SYNDROME TYPE II: A CASE REPORT WITH 3-YEAR FOLLOW-UP. Selcuk Dental Journal, Volume: 10 Issue: 4 Special Issue. https://doi.org/10.15311/selcukdentj.1231513

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