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Journals / Online Türk Sağlık Bilimleri Dergisi / 2026 / Cilt: 5 Sayı: 2

An Analysis of Plasma Thiol/Disulphide Homeostasis in Patients with Stable Angina

Stabil Angina Pektoris Hastalarında Tiyol/Disülfid Homeostazı Analizi

Hayrullah Yazar(SAKARYA ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0001-9447-6322
Esra Yıldız(University Faculty of Art and Sciences, Institute of Natural Sciences)0000-0001-8456-3502
Mustafa Baran İnci(İstanbul Halk Sağlığı Müdürlüğü)0000-0003-1893-5368
Mehmet Akif Çakar(SAKARYA ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0003-3216-4205
Betül Özbek(Ankara Şehir Hastanesi)0000-0003-3355-7801
Ceylan Bal(Ankara Şehir Hastanesi)0000-0002-1678-1281
Özcan Erel(Ankara Şehir Hastanesi)0000-0002-2996-3236
Pages
318–323
Publication Date
2020-06-30
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Objective: To investigate thiol/disulfide homeostasis in patients with stable angina pectoris.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: To investigate thiol/disulfide homeostasis in patients with stable angina pectoris.
📊
Key Findings & Data:Objective: To investigate thiol/disulfide homeostasis in patients with stable angina pectoris.
💡
Conclusion & Impact:Objective: To investigate thiol/disulfide homeostasis in patients with stable angina pectoris.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Serbest tiyol · total tiyol · tiyol/disülfid

Abstract

Objective: To investigate thiol/disulfide homeostasis in patients with stable angina pectoris.

Özet

Amaç: Stabil angina pektoris tanılı hastaların tiyol/disülfid homeostazını incelemektir.

🔖

Cite This Article

Yazar, H., Yıldız, E., İnci, M. B., Çakar, M. A., Özbek, B., Bal, C., Erel, Ö. (2020). An Analysis of Plasma Thiol/Disulphide Homeostasis in Patients with Stable Angina. Online Türk Sağlık Bilimleri Dergisi, Cilt: 5 Sayı: 2, 318–323. https://doi.org/10.26453/otjhs.615454

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References (22)

  1. Valgimigli M, Biscaglia S. Stable angina pectoris. Curr Atheroscler Rep. 2014;16(7):422. doi: 10.1007/s11883-014-0422-4
  2. Collet C, Capodanno D, Onuma Y, et al. Left main coronary artery disease: pathophysiology, diagnosis, and treatment. Nat Rev Cardiol. 2018;15(6):321-331.
  3. Bonomini F, Tengattini S. Atherosclerosis and oxidative stress. Histol Histopathol. 2008;23(3):381-390. doi: 10.14670/HH-23.381
  4. Dzau VJ, Antman EM, Black HR, et al. The cardiovascular disease continuum validated: clinical evidence of improved patient outcomes: part I: Pathophysiology and clinical trial evidence (risk factors through stable coronary artery disease). Circulation. 2006;114(25):2850-2870.
  5. Jones DP, Liang Y. Measuring the poise of thiol/disulfide couples in vivo. Free Radical Bio Med. 2009;47(10):1329-1338. doi: 10.1016/j.freeradbiomed.2009.08.021
  6. Winther JR, Thorpe C. Quantification of thiols and disulfides. BBA-Gen Subjects. 2014;1840 (2):838-846. doi:10.1016/j.bbagen.2013.03.031
  7. Erel O, Neselioglu S. A novel and automated assay for thiol/disulphide homeostasis. Clin Biochem. 2014;47(18):326-332. doi:10.1016/j.clinbiochem.2014.09.026
  8. Ates I, Kaplan M, Yuksel M, et al. Determination of thiol/disulphide homeostasis in type 1 diabetes mellitus and the factors associated with thiol oxidation. Endocrine. 2016;51(1):47-51. doi: 10.1007/s12020-015-0784-6
  9. Ozler S, Erel O, Oztas E, et al. Serum thiol/disulphide homeostasis in preeclampsia. Hypertens Pregnancy. 2015;34 (4):474-485. doi: 10.3109/10641955.2015.1077859
  10. Erkus ME, Altiparmak IH, Akyuz AR, et al. The association between plasma thiol levels and left ventricular diastolic dysfunction in patient with hypertension. Scand J Clin Lab Inv. 2015;75(8):667-673.
  11. Ergin M, Cendek BD. Dynamic thiol-disulfide homeostasis in hyperemesis gravidarum. J Perinatol. 2015;35(10):788-792. doi: 10.1038/jp.2015.81
  12. Kundi H, Ates I, Kiziltunc E, et al. A novel oxidative stress marker in acute myocardial infarction; thiol/disulphide homeostasis. Am J Emerg Med. 2015;33(11):1567-1571. doi: 10.1016/j.ajem.2015.06.016
  13. Ozyazici S, Karateke F, Turan U, et al. A novel oxidative stress mediator in acute appendicitis: Thiol/disulphidehomeostasis. Mediators Inflamm. 2016;10(2):1-6.
  14. Kayacan Y, Yazar H, Cerit G, Ghojebeigloo BE. A new oxidative stress indicator: Effect of 5-hydroxytryptophan on thiol-disulfide homeostasis in exercise. Nutrition. 2019;63(64):114-119. doi: 10.1016/j.nut.2019.01.013
  15. Silver MT, Rose GA, Paul SD, et al. A clinical rule to predict preserved left ventricular ejection fraction in patients after myocardial infarction. Ann intern med. 1994;121(10):750-756. doi:10.7326/0003-4819-121-10-199411150-00004
  16. Ellman G, Lysko H. A precise method for the determination of whole blood and plasma sulfhydryl groups. Anal Biochem. 1979;93(1):98-102.
  17. Ates I, Ozkayar N, Altay M, et al. Is disulphide/thiol ratio related to blood pressure in masked hypertension?. Clin Exp Hypertens. 2016;38(2):150-154.
  18. Yuvaci HU, Akdemir N, Bostanci MS, et al. Evaluation of the level of thiol-disulphide homeostasis in patients with mild and severe preeclampsia. Pregnancy Hypertens. 2016;6(4):394-399. doi: 10.1016/j.preghy.2016.09.003
  19. Elmas B, Erel Ö, Ersavaş D, Yürümez Y. Thiol/disulfide homeostasis as a novel indicator of oxidative stress in children with simple febrile seizures. Neurol Sci. 2017;38(11):1969-1975. doi: 10.1007/s10072-017-3087-2
  20. Kayacan Y, Yazar H, Kisa EC, Ghojebeigloo BE. A novel biomarker explaining the role of oxidative stress in exercise and l-tyrosine supplementation: thiol/disulphide homeostasis. Arch Physiol Biochem. 2018;124(3):232-236. doi: 10.1080/13813455.2017.1388410
  21. Dirican N, Dirican A, Sen O, et al. Thiol/disulfide homeostasis: A prognostic biomarker for patients with advanced non-small cell lung cancer?. Redox Rep. 2016;21(5):197-203. doi: 10.1179/1351000215Y.0000000027
  22. Erel O. A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation. Clin Biochem. 2004;37(4):277-285. doi: 10.1016/j.clinbiochem.2003.11.015