SavedAdd your journal

Journals / TSK Koruyucu Hekimlik Bülteni / 2011 / Cilt: 10 - Sayı: 6

[Determination of regularities in histochemical changes of internal organs under acute alcoholic intoxications in Russia]

Rusya'da akut alkol zehirlenmelerinde, iç organ histopatolojik değişikliklerinin değerlendirilmesi

Vugar MAMMADOV
Pages
641–648
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

CONCLUSION: Study suggests that morpho-functional histochemical tests must be entered in the list of methods of postmortem diagnostics during autopsies of cases with the background of ethanol poisoning, especially for differential diagnosis of acute alcohol intoxication, alcohol cardiomyopathy and ischemic heart disease.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:AIM: During forensic-medical autopsies experts must very often assess degree and the role of acute alcohol intoxications in mechanisms of death.
📊
Key Findings & Data:METHOD: Epidemiological screening of 320 medico-legal reports assesses the role of sex, age, ethnicity and other peculiarities.
💡
Conclusion & Impact:CONCLUSION: Study suggests that morpho-functional histochemical tests must be entered in the list of methods of postmortem diagnostics during autopsies of cases with the background of ethanol poisoning, especially for differential diagnosis of acute alcohol intoxication, alcohol cardiomyopathy and ischemic heart disease.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

AIM: During forensic-medical autopsies experts must very often assess degree and the role of acute alcohol intoxications in mechanisms of death. This becomes more actual in the cases of sudden death from different diseases especially cardiac, brain and liver origin, mechanical injuries, mechanical asphyxia etc. This study aims to show that blood concentration of alcohol must not be only criteria during assessment of severity of intoxications and their influence on tanatogenesis. METHOD: Epidemiological screening of 320 medico-legal reports assesses the role of sex, age, ethnicity and other peculiarities. RESULT: Special histochemical investigations of ethanol oxidizing enzymes were also conducted on materials taken from 167 autopsies. CONCLUSION: Study suggests that morpho-functional histochemical tests must be entered in the list of methods of postmortem diagnostics during autopsies of cases with the background of ethanol poisoning, especially for differential diagnosis of acute alcohol intoxication, alcohol cardiomyopathy and ischemic heart disease.

Özet

AMAÇ: Adli tıp otopsilerinde uzmanlar sıklıkla akut alkol zehirlenmesinin ölüm mekanizması üzerine etkisinin derecesini değerlendirmek zorundadırlar. Bu özellikle kalp, beyin ve karaciğer nedenli, mekanik yaralanmalar ve mekanik asfiksi gibi ani ölümlerde daha önemli hale gelmektedir. Bu çalışma kan alkon konsantrasyonunun tekbaşına intoksikasyon ciddiyet değerlendirme kriteri olmaması gerektiği ve bunun patogeneze etkisinin gösterilmesi amaçlanmıştır. YÖNTEM: Üçyüz yirmi tıbbi-hukuki rapor cinsiyet, yaş, etnisite ve diğer özelliklerin etkisinin değerlendirilmesi amacıyla tarandı. BULGULAR: Etanol okside edici enzimi özel histokimyasal incelemesi 167 otopsiden alınan materyalde yapıldı. SONUÇ: Çalışma; morfo-fonksiyonel histokimyasal testlerin, etanol zehirlenmesi kökeni olan, özellikle akut alkol zehirlenmesinin olkol kardiyomiyopatisi ve iskemik kalp hastalığından ayırıcı tanısında postmortem tanısal otopsiye eklenmesi gerektiğini desteklemektedir.

🔖

Cite This Article

MAMMADOV, V. (2011). [Determination of regularities in histochemical changes of internal organs under acute alcoholic intoxications in Russia]. TSK Koruyucu Hekimlik Bülteni, Cilt: 10 - Sayı: 6, 641–648. https://ajindex.com/articles/129162

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (16)

  1. Kapustin A.V. Determination of alcohol intoxications role in tanatogenesis. Forensic examination. 1999; 42(6): 10-12
  2. Viter V.I, Permyakov AV. Alcoholemia in forensic-medical practice. Contemporary problems of forensic medicine and expert practice. Izhevsk. 1997; 9: 25-29
  3. Kapustin AV., Panfilenko OA, Serebrakova TG. Determination of severity of alcohol intoxication. Forensic examination. 2002; 45(3): 3-5
  4. Gallant DM., Pena JM. One more look at alcohol consumption and risk of coronary disease. Alcoholism: Clin.and Exp. Res. 1992; 16(2): 350
  5. Viter VI, Tolstolutsky VY. Causa proxima of death from acute alcoholic intoxication. Urgent aspects of forensic medicine. Izhevsk. Ekspertiza. 1995; 4: 20-26
  6. Kapustin AV. Blood concentration of alcohol. Forensic examination. 2000; 43(1): 7-11
  7. Kapustin AV. On assessment of alcoholic intoxication degree. Forensic examination. 1994; 37(4): 17-20
  8. Ameno К, Ameno S, Fuke Ch, et al. A survival case with an unusually high blood ethanol concentration. Jap. J. Leg. Med. 1988; 42(3): 345-347
  9. Tomilin VV, Kapustin AV. Most urgent scientific problems of contemporary forensic medicine. Identification problems in forensic medical theory and practice. The materials of IV Russian Congress of forensic physicians. Moscow: Vladimir. 1996, p. 5-6
  10. Viter VI, Permyakov AV. Several aspects of ischemic heart disease and acute ethanol intoxication. Urgent aspects of forensic medicine. Izhevsk: Expertiza. 1993; 3: 32-35
  11. Galeyeva LS. Forensic assessment of morphological changes in human brain and internals under alcoholic intoxication. Novosibirsk: autoreferat of PHD dissertation. 1973, p. 20
  12. Capaeso JM, Peng Li, Guindery G, Malhotra A, Cortesi R, Anversa P. Myocardial mechanical, biochemical and structural alteratious induced by chronic ethanol ingestion in rats. Circ. Res. 1992. 71(2): 346- 356
  13. Bogomolova IN, Bogomolov DV, Pigolkin YI, Bukeshov MK, Mammadov VG, Morozov YY. Forensic-medical diagnostics of ethanol and its surrogates poisonings by morphological data. Moscow: Medical Information Agency. 2003, p. 438
  14. Paukov VS, Ugrumov AI. Pathological anatomy of alcoholic disease (review). News of Science and Technique. Series of medical releases. Alcoholic disease. Moscow: VINITI. 1997; 5: 1-4
  15. Ugrumov A. Organic pathology and causes of death of persons making excessive use of alcohol. Problems ob Narcology. 1990; 3: 47- 50
  16. Tsiplenkova VG. Alcoholic cardiomyopathy and sudden heart deat