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Journals / TSK Koruyucu Hekimlik Bülteni / 2011 / Cilt: 10 - Sayı: 4

Nasopharyngeal Carriage Rate and Serogroups of Neisseria Meningitidis in Turkish Recruits upon Entry to the Military

Askere Yeni Katılan Türk Askerlerinde Neisseria Meningitidis Nazofaringeal Taşıyıcılık Oranı ve Serogrupları

A. Celal BAŞUSTAOĞLU
ORHAN BEDİR
Soner YILMAZ
Abdullah KILIÇ
RAMAZAN GÜMRAL
Gürkan MERT
Bülent BEŞİRBELLİOĞLU
Pages
447–450
DOI
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CONCLUSION: Since serogroup Y and W-135 are predominant in this study population, it was suggest that Turkish recruits should be vaccinated by quadrivalent vaccine (A,C,Y, and W-135) upon the military instead of A+C polysaccharide vaccine and now quadrivalent vaccine has been carried out

📌 3 Key Takeaways

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Objective & Hypothesis:AIM: The aim of this study was to determine nasopharyngeal carriage rate and serogroup of Neisseria meningitidis strains isolated from Turkish recruits upon entry to the military.
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Key Findings & Data:METHOD: Nasopharyngeal swab samples were obtained from 1995 soldiers and were inoculated immediately on BBL-modified Thayer-Martin medium plates.
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Conclusion & Impact:CONCLUSION: Since serogroup Y and W-135 are predominant in this study population, it was suggest that Turkish recruits should be vaccinated by quadrivalent vaccine (A,C,Y, and W-135) upon the military instead of A+C polysaccharide vaccine and now quadrivalent vaccine has been carried out
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

AIM: The aim of this study was to determine nasopharyngeal carriage rate and serogroup of Neisseria meningitidis strains isolated from Turkish recruits upon entry to the military. METHOD: Nasopharyngeal swab samples were obtained from 1995 soldiers and were inoculated immediately on BBL-modified Thayer-Martin medium plates. The plates were examined for the presence of colonies showing the typical morphology of N. meningitidis. Suspect colonies were screened for oxidase reactivity, and positive colonies were Gram stained. If Gram-negative diplococci were present, a biochemical profile by the API NH system was used for confirmation. Serogrouping of the meningococcal isolates was performed by a slide agglutination technique. RESULTS: The nasopharyngeal carriage rate of N. meningitidis was found to be 4.2% (n=83). Of these meningococci, 15.6% (n=13) were serogroup Y, 10.8% (n=9) were serogroup W-135, 9.6% (n=8) were serogroup C, 6.1% (n=5) were serogroup B, 2.4% (n=2) were serogroup A. The 46 isolates (55.4%) were detected as nonserogroupable. CONCLUSION: Since serogroup Y and W-135 are predominant in this study population, it was suggest that Turkish recruits should be vaccinated by quadrivalent vaccine (A,C,Y, and W-135) upon the military instead of A+C polysaccharide vaccine and now quadrivalent vaccine has been carried out

Özet

AMAÇ: Bu çalışmanın amacı askere yeni katılan Türk askerlerinde izole edilen Neisseria meningitidis nazofaringeal taşıyıcılık oranı ve serogruplarının tespit edilmesidir. YÖNTEM: 1995 askerden nazofaringeal silgeç örnekleri toplandı ve BBL modifiye Thayer-Martin agar plaklarına ekimi yapıldı. Plaklar tipik N. meningitidis kolonisi oluşturması yönünde değerlendirildi. Şüpheli kolonilerin oksidaz aktivitesi değerlendirildi ve pozitif olanlar Gram ile boyandı. Gram negatif diplokok görüntüsü veren izolatlar API NH sistem kullanılarak doğrulandı. Meningokok izolatlarının serogruplandırılması slayt aglütinasyon yöntemi ile yapıldı. BULGULAR: N. meningitidis nazofaringeal taşıyıcılık oranı %4,2 (n=83) olarak bulundu. Meningokokların %15,6'sı (n=13) serogrup Y, %10,8'i (n=9) serogrup W-135, %9,6'sı (n=8) serogrup C, %6,1'i (n=5) serogrup B ve %2,4'ü (n=2) serogrup A idi. Kırkaltı izolat (%55,4) serogruplandırılmayan grup olarak tespit edildi. SONUÇ: Çalışmada serogrup Y ve serogrup W-135 baskın olduğu için, Türk ordusuna yeni katılan erlere A+C polisakkarit aşı yerine dörtlü aşı (A, C, Y ve W-135) yapılması önerilmiş ve şu an dörtlü aşı uygulanmaktadır

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Cite This Article

BAŞUSTAOĞLU, A. C., BEDİR, O., YILMAZ, S., KILIÇ, A., GÜMRAL, R., MERT, G., BEŞİRBELLİOĞLU, B. (2011). Nasopharyngeal Carriage Rate and Serogroups of Neisseria Meningitidis in Turkish Recruits upon Entry to the Military. TSK Koruyucu Hekimlik Bülteni, Cilt: 10 - Sayı: 4, 447–450. https://ajindex.com/articles/129123

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