Journals / Marmara Medical Journal / 2026 / Volume: 37 Issue: 1

Patients’ characteristics and procedural outcomes of premature ventricular complex ablation: Data of a single-centre arrhythmia unit experience

Serdar Demır(Kartal Koşuyolu Heart and Vascular Disease Research and Training Hospital)0000-0001-5320-3248
Ayhan Kup(Kartal Koşuyolu Heart and Vascular Disease Research and Training Hospital)0000-0002-5969-8402
Kamil Gulsen(Kartal Koşuyolu Heart and Vascular Disease Research and Training Hospital)0000-0003-1103-0013
Abdulkadir Uslu(Kartal Koşuyolu Heart and Vascular Disease Research and Training Hospital,)0000-0002-7841-7952
Ayhan Tosun(Kartal Koşuyolu Heart and Vascular Disease Research and Training Hospital,)0000-0001-9035-8839
Mehmet Çelik(Kartal Koşuyolu Heart and Vascular Disease Research and Training Hospital,)0000-0003-4721-3743
Taylan Akgun(Kartal Koşuyolu Heart and Vascular Disease Research and Training Hospital,)0000-0002-5395-2027
Alper Kepez(MARMARA UNIVERSITY)0000-0003-3868-3268
Pages
—
Publication Date
2024-01-28
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Most PVCs originate from the right or left ventricular outflow tract.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Premature ventricular complexes (PVCs) are common arrhythmias and catheter ablation (CA) is the major treatment in patients with PVCs.
📊
Key Findings & Data:Patients and Methods: We investigated consecutive patients who had undergone CA because of PVCs between January 2015 and March 2021 in a single centre arrhythmia unit.
💡
Conclusion & Impact:Most PVCs originate from the right or left ventricular outflow tract.
🔬Design:Research Article
📍Scope:2015 Verileri
⚙️Variables:Premature ventricular complexes · Catheter ablation · Outflow tract

Abstract

Objective: Premature ventricular complexes (PVCs) are common arrhythmias and catheter ablation (CA) is the major treatment in patients with PVCs. In this study, we aimed to share our experience on PVCs patients who had undergone CA. Patients and Methods: We investigated consecutive patients who had undergone CA because of PVCs between January 2015 and March 2021 in a single centre arrhythmia unit. Patients’ characteristics, rhythm Holter recordings, echocardiography results and CA outcomes were noted. Patients were followed up for 22.3±3.7 months. Descriptive statistics were used to demonstrate features of study patients. Results: Study population consisted of 645 patients; mean age was 51 ± 4.14 and 372 (57.7%) were male. Arrhythmia originated from the right ventricular outflow tract in 279 (46.6 %) patients, coronary cusps in 161 (26.9 %) patients, left ventricle summit in 50 (8.3%) patients and inside of the right or left ventricle in remaining patients. Sustained procedural success was achieved in 526 (88.1 %) patients. Recurrence was observed in 46 (6.7%) patients during follow-up. Major complication occurred in two patients (one procedural mortality due to coronary artery injury and one tamponade). Conclusion: Premature ventricular contraction ablation can be utilized safely with high success rate. Most PVCs originate from the right or left ventricular outflow tract.

🔖

Cite This Article

Demır, S., Kup, A., Gulsen, K., Uslu, A., Tosun, A., Çelik, M., Yıldırım, C., Akgun, T., Kepez, A. (2024). Patients’ characteristics and procedural outcomes of premature ventricular complex ablation: Data of a single-centre arrhythmia unit experience. Marmara Medical Journal, Volume: 37 Issue: 1. https://doi.org/10.5472/marumj.1378571

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (20)

  1. Ng GA. Treating patients with ventricular ectopic beats. Heart 2006;92: 1707–12. doi: 10.1136/hrt.2005.067843
  2. Kennedy HL, Whitlock JA, Sprague MK, et al. Long-term follow-up of asymptomatic healthy subjects with frequent and complex ventricular ectopy. N Engl J Med 1985;312:193-7. 1985;312:193-7. doi: 10.1056/NEJM198.501.243120401.
  3. Lee AK, Deyell MW. Premature ventricular contractioninduced cardiomyopathy. Curr Opin Cardiol 2016;31:1-10. doi: 10.1097/HCO.000.000.0000000236
  4. Kobayashi Y. Idiopathic ventricular premature contraction and ventricular tachycardia: distribution of the origin, diagnostic algorithm, and catheter ablation. J Nippon Med Sch 2018;85:87-94. doi: 10.1272/jnms.2018_85-14.
  5. Zhong L, Lee YH, Huang XM, et al. Relative efficacy of catheter ablation vs antiarrhythmic drugs in treating premature ventricular contractions: a single-center retrospective study. Heart Rhythm 2014;11:187-93. doi: 10.1016/j. hrthm.2013.10.033
  6. Lang RM, Badano LP, Mor‐Avi V, et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. Eur Heart J Cardiovasc Imaging 2015;16:233-70. doi: 10.1016/j. echo.2014.10.003
  7. Drew BJ, Califf RM, Funk M, Kaufman ES, et al. American Heart Association. AHA scientific statement: practice standards for electrocardiographic monitoring in hospital settings: an American Heart Association Scientific Statement from the Councils on Cardiovascular Nursing, Clinical Cardiology, and Cardiovascular Disease in the Young: endorsed by the International Society of Computerized electrocardiology and the American Association of Critical- Care Nurses. J Cardiovasc Nurs 2005;20:76-106. doi: 10.1097/00005.082.200503000-00003
  8. Hingorani P, Karnad DR, Rohekar P, et al. Arrhythmias seen in baseline 24-hour holter ecg recordings in healthy normal volunteers during phase 1 clinical trials. J Clin Pharmacol 2016;56:885-93. doi: 10.1002/jcph.679
  9. Tran CT, Calkins H. Premature ventricular contraction-induced cardiomyopathy: an emerging entity. Expert Rev Cardiovasc Ther 2016;14:1227-34. doi: 10.1080/14779.072.2016.1222901.
  10. Ling Z, Liu Z, Su L, et al. Radiofrequency ablation versus antiarrhythmic medication for treatment of ventricular premature beats from the right ventricular outflow tract: prospective randomized study. Circ Arrhythm Electrophysiol 2014;7: 237-43. doi: 10.1161/CIRCEP.113.000805
  11. Beiert T, Knappe V, Tiyerili V, et al. Chronic lower-dose relaxin administration protects from arrhythmia in experimental myocardial infarction due to anti-inflammatory and antifibrotic properties. Int J Cardiol 2018;250:21-8. doi: 10.1016/j. ijcard.2017.09.017.
  12. Komatsu Y, Hocini M, Nogami A, et al. Catheter ablation of refractory ventricular fibrillation storm after myocardial infarction. Circulation 2019;139:2315-25. doi: 10.1161/ CIRCULATIONAHA.118.037997.
  13. Marcus GM. Evaluation and management of premature ventricular complexes. Circulation 2020;141:1404-18. doi: 10.1161/CIRCULATIONAHA.119.042434
  14. Fedida J, Strisciuglio T, Sohal M, et al. Efficacy of advanced pace-mapping technology for idiopathic premature ventricular complexes ablation. J Interv Card Electrophysiol 2018;51:271- 7. doi: 10.1007/s10840.018.0320-8.
  15. Lamba JL, Redfearn DP, Michael KA, et al. Radiofrequency catheter ablation for the treatment of idiopathic premature ventricular contractions originating from the right ventricular outflow tract: a systematic review and metaanalysis. Pacing Clin Electrophysiol 2014;37:73-8. doi: 10.1111/pace.12243
  16. Zang M, Zhang T, Mao J, et al. Beneficial effects of catheter ablation of frequent premature ventricular complexes on left ventricular function. Heart 2014;100:787-93. doi: 10.1136/ heartjnl-2013-305175
  17. Lee AK, Deyell MW. Premature ventricular contractioninduced cardiomyopathy. Curr Opin Cardiol 2016;31:1-10. doi: 10.1097/HCO.000.000.0000000236
  18. Tran CT, Calkins H. Premature ventricular contraction-induced cardiomyopathy: an emerging entity. Expert Rev Cardiovasc Ther 2016;14:1227-34. doi: 10.1080/14779.072.2016.1222901.
  19. Beiert T, Knappe V, Tiyerili V, et al. Chronic lower-dose relaxin administration protects from arrhythmia in experimental myocardial infarction due to anti-inflammatory and antifibrotic properties. Int J Cardiol 2018;250:21-8. doi: 10.1016/j. ijcard.2017.09.017.
  20. Fedida J, Strisciuglio T, Sohal M, et al. Efficacy of advanced pace-mapping technology for idiopathic premature ventricular complexes ablation. J Interv Card Electrophysiol 2018;51:271- 7. doi: 10.1007/s10840.018.0320-8.