Journals / Sakarya Tıp Dergisi / 2026 / Volume: 9 Issue: 2

Are Neutrophil, Platelet, and Eosinophil-to-Lymphocyte Ratio and Mean Platelet Volume Really Potential Predictor for Otitis Media with Chronic Effusion?

Nötrofil, Platelet, Eosinofil/Lenfosit Oranları ve MPV’nin Efüzyonlu Otitis Media Tanısında Gerçekten Potansiyel Rolü Var mı?

Oğuz Kadir Eğilmez(SAKARYA SAĞLIK BAKANLIĞI SAKARYA ÜNİVERSİTESİ EĞİTİM VE ARAŞTIRMA HASTANESİ)0000-0001-9623-9152
Mehmet Güven(SAKARYA SAĞLIK BAKANLIĞI SAKARYA ÜNİVERSİTESİ EĞİTİM VE ARAŞTIRMA HASTANESİ)
Mahmut Sinan Yılmaz(SAKARYA SAĞLIK BAKANLIĞI SAKARYA ÜNİVERSİTESİ EĞİTİM VE ARAŞTIRMA HASTANESİ)
Deniz Demir(SAKARYA SAĞLIK BAKANLIĞI SAKARYA ÜNİVERSİTESİ EĞİTİM VE ARAŞTIRMA HASTANESİ)
Bilgehan Çelik(SAKARYA SAĞLIK BAKANLIĞI SAKARYA ÜNİVERSİTESİ EĞİTİM VE ARAŞTIRMA HASTANESİ)
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Publication Date
2019-06-28
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It is clear that further studies with large numbers of subjects are needed.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Otitis media with effusion is an inflammatory disease characterized by fluid accumulation in the middle ear.
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Key Findings & Data:Materials and Methods: In our study, we retrospectively analyzed 69 patients (44 male, 25 female) between the ages of 18-50 having only chronic otitis media with effusion, and 69 age- and sex matched (between ages of 18-50; 38 male, 31 female) healthy controls.
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Conclusion & Impact:It is clear that further studies with large numbers of subjects are needed.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:otitis media with effusion · neutrophil / lymphocyte ratio · platelet / lymphocyte ratio

Abstract

Objective: Otitis media with effusion is an inflammatory disease characterized by fluid accumulation in the middle ear. The aim of this study is to investigate the predictive role of neutrophil, platelet, and eosinophil-to-lymphocyte ratio and mean platelet volume in adult patients having otitis media with effusion and to compare with control subjects; analyse whether they could be a potential predictor parameter to predict the disease progression. Materials and Methods: In our study, we retrospectively analyzed 69 patients (44 male, 25 female) between the ages of 18-50 having only chronic otitis media with effusion, and 69 age- and sex matched (between ages of 18-50; 38 male, 31 female) healthy controls. Study and control groups were compared with each other for MPV, neutrophil-to-lymphocyte, platelet-to-lymphocyte, and eosinophil-to-lymphocyte ratios. Results: NLR, PLR, ELR and MPV values in the patient group were 1.97, 112.69, 0.08 and 7.75 and the mean value of the control group was 1.90, 114.58, 0.06 and 7.62, respectively. There was no statistically significant difference between the groups (p = 0.646, 0.843, 0.16, 0.769, respectively). Conclusion : Although there are other studies in the literature, we think that these values do not have a predictive value in the diagnosis of EOM. It is clear that further studies with large numbers of subjects are needed.

Özet

Amaç: Efüzyonlu otitis media (EOM), orta kulakta sıvı birikimi ile karakterize inflamatuar bir hastalıktır. Bu çalışmanın amacı, EOM’li erişkin hastalarda nötrofil, platelet ve eozinofil-lenfosit oranı ve ortalama platelet hacminin prediktif rolünü araştırıp kontrol denekleri ile karşılaştırmak ve hastalığın ilerlemesini tahmin etmek için potansiyel bir belirleyici parametre olup olmadığını analiz etmektir. Gereç ve Yöntemler: Çalışmamızda 18-50 yaşları arasında sadece effüzyonlu kronik otitis media'lı 69 hasta (44 erkek, 25 kadın) ve yaş ve cinsiyet eşleştirilmiş 69 sağlıklı kontrol deneği (yaş aralığı 18-50; 38 erkek, 31 kadın) retrospektif olarak incelendi. Çalışma ve kontrol grupları, MPV, nötrofil-lenfosit, trombosit-lenfosit ve eozinofil-lenfosit oranları için birbirleriyle karşılaştırıldı. Bulgular: Hasta grubunda NLR, PLR, ELR ve MPV değerleri sırası ile 1,97; 112,69; 0,08 ve 7,75 olarak saptanırken kontrol grubunda sırası ile 1,90; 114,58; 0,06 ve 7,62 olarak bulundu ve gruplar arasında istatistiksel olarak anlamlı fark saptanmadı (sırasıyla p= 0.646, 0.843, 0.16, 0.769). Sonuç: Literatürde her ne kadar aksini belirten çalışmalar olsa da biz EOM tanısında bu değerlerin prediktif bir değerinin olmadığını düşünmekteyiz. Fazla sayıda denekle ileri çalışmalara ihtiyaç olduğu açıktır.

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Cite This Article

Eğilmez, O. K., Güven, M., Yılmaz, M. S., Demir, D., Çelik, B. (2019). Are Neutrophil, Platelet, and Eosinophil-to-Lymphocyte Ratio and Mean Platelet Volume Really Potential Predictor for Otitis Media with Chronic Effusion?. Sakarya Tıp Dergisi, Volume: 9 Issue: 2. https://doi.org/10.31832/smj.512224

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