Journals / Sakarya Tıp Dergisi / 2026 / Volume: 16 Issue: 3

Observations on Traumatic Wound Dehiscence Following Corneal Transplantation

Erel İçel(İZMİR CITY HOSPITAL, DEPARTMENT OF OPHTHALMOLOGY)0000-0001-7150-5581
Bora Yüksel(İZMİR CITY HOSPITAL, DEPARTMENT OF OPHTHALMOLOGY)0000-0001-5998-9122
Mehmet Han Lale(İZMİR CITY HOSPITAL, DEPARTMENT OF OPHTHALMOLOGY)0000-0003-4232-5682
Tuncay Küsbeci(İZMİR CITY HOSPITAL, DEPARTMENT OF OPHTHALMOLOGY)0000-0002-5169-4140
İpek Çıkmazkara(İZMİR CITY HOSPITAL, DEPARTMENT OF OPHTHALMOLOGY)0000-0002-2013-0449
Pages
—
Publication Date
2026-09-30
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Early treatment improves outcomes, highlighting the importance of patient education and protective eyewear use.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: To describe the clinical characteristics of traumatic wound dehiscence after penetrating keratoplasty and to evaluate the associated visual, anatomical, and graft-related outcomes.
📊
Key Findings & Data:Methods: Cases of wound dehiscence following penetrating keratoplasty, treated from 2012 to 2025, were evaluated retrospectively.
💡
Conclusion & Impact:Early treatment improves outcomes, highlighting the importance of patient education and protective eyewear use.
🔬Design:Research Article
📍Scope:2012 Verileri
⚙️Variables:Cornea · Corneal transplantation · Penetrating keratoplasty

Abstract

Objective: To describe the clinical characteristics of traumatic wound dehiscence after penetrating keratoplasty and to evaluate the associated visual, anatomical, and graft-related outcomes. Methods: Cases of wound dehiscence following penetrating keratoplasty, treated from 2012 to 2025, were evaluated retrospectively. Data were extracted from the medical records of 33 patients, identified among 1632 patients who had previously undergone penetrating keratoplasty. Patient records were examined to determine the type and timing of the injury, corrected distance visual acuity (CDVA), and clinical outcomes. Results: Across 1632 keratoplasties, 33 traumatic dehiscence events were recorded (2.0%). A total of 33 patients, including 9 females (27.3%) and 24 males (72.7%), with a mean age of 57.03 ± 17.43 years (range: 24–89), were included in the analysis. The most common indication for penetrating keratoplasty (PK) was pseudophakic bullous keratopathy (PBK), accounting for 33.3% of cases. In the present study, the median time from keratoplasty to traumatic wound dehiscence was 29 months (range: 4–177 months). At the final follow-up, the mean CDVA was 2.02±0.7 LogMAR (range: 0.22–3.0). Conclusions: Traumatic wound dehiscence is a lifelong risk after penetrating keratoplasty due to persistent wound fragility. Even minor trauma can cause severe vision loss years post-surgery. Early treatment improves outcomes, highlighting the importance of patient education and protective eyewear use.

🔖

Cite This Article

İçel, E., Yüksel, B., Lale, M. H., Küsbeci, T., Çıkmazkara, İ. (2026). Observations on Traumatic Wound Dehiscence Following Corneal Transplantation. Sakarya Tıp Dergisi, Volume: 16 Issue: 3. https://doi.org/10.31832/smj.1846069

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (23)

  1. Price FW, Price MO. Adult keratoplasty: has the prognosis improved in the last 25 years? Int Ophthalmol. 2008; 28:141-6. doi:10.1007/s10792-007-9183-1.
  2. Naydis I, Klemm M, Hassenstein A, Richard G, Katz T, Linke SJ. Postkeratoplasty astigmatism: comparison of three suturing techniques. Ophthalmologe.2011;108:252-9. doi:10.1007/s00347-010-2272-y.
  3. Bowman RJ, Yorston D, Aitchison TC, McIntyre B, Kirkness CM. Traumatic wound rupture after penetrating keratoplasty in Africa. Br J Ophthalmol. 1999;83:530-4. doi:10.1136/bjo.83.5.530.
  4. Farley MK, Pettit TH. Traumatic wound dehiscence after penetrating keratoplasty. Am J Ophthalmol. 1987;104:44-9. doi:10.1016/0002-9394(87)90291-1.
  5. Steinberg J, Eddy MT, Katz T, Fricke OH, Richard G, Linke SJ. Traumatic wound dehiscence after penetrating keratoplasty: case series and literature review. Eur J Ophthalmol. 2012;22(3):335-41. doi:10.5301/ejo.5000057.
  6. Lam FC, Rahman MQ, Ramaesh K. Ramaesh. Traumatic wound dehiscence after penetrating keratoplasty-a cause for concern. Eye. 2007;21(9):1146-50. doi:10.1038/sj.eye.6702407.
  7. Zheng N, He W, Zhu S. Incidence of wound dehiscence after keratoplasty: a meta-analysis of observational studies. Front Med (Lausanne). 2023;10:1187555. doi:10.3389/fmed.2023.1187555.
  8. Jafarinasab MR, Feizi S, Esfandiari H, Kheiri B, Feizi M. Traumatic wound dehiscence following corneal transplantation. J Ophthalmic Vis Res. 2012;7(3):214-8.
  9. Kawashima M, Kawakita T, Shimmura S, Tsubota K, Shimazaki J. Characteristics of traumatic globe rupture after keratoplasty. Ophthalmology. 2009;116(11):2072-6. doi:10.1016/j.ophtha.2009.04.047.
  10. Yıldırım M, Keleş S. Traumatic wound dehiscence after penetrating keratoplasty: a retrospective analysis. Nagoya J Med Sci. 2025;87(4):742-6. doi:10.18999/nagjms.87.4.742.
  11. Şingar Özdemir E, Burcu A, Yalnız Akkaya Z, Oral B, Örnek F. Wound dehiscence after penetrating keratoplasty. Ulus Travma Acil Cerrahi Derg. 2018;24:563-8. doi:10.5505/tjtes.2018.44450.
  12. Barut Selver Ö, Palamar M, Eğrilmez S, Yağcı A. Traumatic wound dehiscence after penetrating keratoplasty. Ulus Travma Acil Cerrahi Derg. 2016;22:437-40. doi:10.5505/tjtes.2016.26963.
  13. Foroutan AR, Gheibi GH, Joshaghani M, Ahadian A, Foroutan P. Traumatic wound dehiscence and lens extrusion after penetrating keratoplasty. Cornea. 2009;28(10):1097-9. doi:10.1097/ICO.0b013e3181a1645e.
  14. Rehany U, Rumelt S. Ocular trauma following penetrating keratoplasty: incidence, outcome, and postoperative recommendations. Arch Ophthalmol. 1998;116(10):1282-6. doi:10.1001/archopht.116.10.1282.
  15. Tseng SH, Lin SC, Chen FK. Traumatic wound dehiscence after penetrating keratoplasty: clinical features and outcome in 21 cases. Cornea. 1999;18(5):553-8.
  16. Raber IM, Arentsen JJ, Laibson PR. Traumatic wound dehiscence after penetrating keratoplasty. Arch Ophthalmol. 1980 Aug;98(8):1407-9. doi:10.1001/archopht.1980.01020040259009.
  17. Figueiredo F, Sandhu J, Shaw M. Clinical outcomes of traumatic globe rupture in corneal graft patients. Int Ophthalmol. 2024;44(1):120. doi:10.1007/s10792-024-03008-w.
  18. Das S, Whiting M, Taylor HR. Corneal wound dehiscence after penetrating keratoplasty. Cornea. 2007;26:526-9. doi:10.1097/ICO.0b013e318038d2e8.
  19. Topping TM, Stark WJ, Maumenee E, Kenyon KR. Traumatic wound dehiscence following penetrating keratoplasty. Br J Ophthalmol. 1982;66:174-8. doi:10.1136/bjo.66.3.174.
  20. Agrawal V, Wagh M, Krishnamachary M, Rao GN, Gupta S. Traumatic wound dehiscence after penetrating keratoplasty. Cornea. 1995;14:601-3. doi:10.1097/00003226-199511000-00013.
  21. Nagra PK, Hammersmith KM, Rapuano CJ, Laibson PR, Cohen EJ. Wound dehiscence after penetrating keratoplasty. Cornea. 2006;25:132-5. doi:10.1097/01.ico.0000179926.74780.b2.
  22. Filipec M, Phan TM, Zhao TZ, Rice BA, Merchant A, Foster CS. Topical cyclosporine a and corneal wound healing. Cornea. 1992;11:546-52. doi:10.1097/00003226-199211000-00011.
  23. Liang H, Baudouin C, Daull P, Garrigue JS, Brignole-Baudouin F. Ocular safety of cationic emulsion of cyclosporine in an in vitro corneal wound-healing model and an acute in vivo rabbit model. Mol Vis. 2012;18:2195-204.