SavedAdd your journal

Journals / Süleyman Demirel Üniversitesi Fen Edebiyat Fakültesi Fen Dergisi / 2015 / Volume: 10 Issue: 2

Production Cross–Section Calculations of Medical125I Radionuclide Using α, d and γ Induced Reactions

Tıbbi125I Radyonüklidininα, d ve γ Girişli Reaksiyonlar Kullanılarak Üretim Tesir Kesitlerinin Hesaplanması

Bayram Demir
Veli Çapalı
İsmail Sarpün
Abdullah Kaplan
Pages
—
Publication Date
2015-11-22
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

EMPIRE 3.1 Exciton and Generalized Superfluid models are recommended, if experimental production cross–section of 125Iradionuclide data are not available to produce because of the experimental difficulties

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Iodine radioisotopes are the most important radioisotopes used in the medicine, especially 125I. 125I is used in radiation therapy as brachytherapy source to treat prostate cancer and brain tumors.
📊
Key Findings & Data:In this study, production cross–section calculations of 125Iradionuclide used in medicine produced by 123Sb (α,2n)125I, 124Te(d,n)125I, and 127 I(γ,2n)125I reactions have been investigated in the different incident energy range up to 40 MeV.
💡
Conclusion & Impact:EMPIRE 3.1 Exciton and Generalized Superfluid models are recommended, if experimental production cross–section of 125Iradionuclide data are not available to produce because of the experimental difficulties
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:125I · EMPIRE 3.1

Abstract

Iodine radioisotopes are the most important radioisotopes used in the medicine, especially 125I. 125I is used in radiation therapy as brachytherapy source to treat prostate cancer and brain tumors. In this study, production cross–section calculations of 125Iradionuclide used in medicine produced by 123Sb (α,2n)125I, 124Te(d,n)125I, and 127 I(γ,2n)125I reactions have been investigated in the different incident energy range up to 40 MeV. Two–Component Exciton and Generalized Superfluid models of the TALYS 1.6 code and Exciton and Generalized Superfluid models of the EMPIRE 3.1 code have been used to perform calculations. The calculated results have been compared with the experimental results taken fromthe Experimental Nuclear Reaction Data Library (EXFOR). EMPIRE 3.1 Exciton and Generalized Superfluid models are recommended, if experimental production cross–section of 125Iradionuclide data are not available to produce because of the experimental difficulties

Özet

Özellikle 125I olmak üzere, iyot radyoizotopları tıpta kullanılan en önemli izotoplardır. 125I, prostat kanseri ve beyin tümörlerini tedavi etmek için radyasyon tedavisinde brakterapi kaynağı olarak kullanılır. Bu çalışmada, 40 MeV'e kadar farklı gelme enerjilerinde 23Sb (α,2n)125I, 124Te(d,n)125I, ve 127 I(γ,2n)125I reaksiyonları ile 125I radyonüklidin üretim tesir kesiti hesaplamaları araştırılmıştır. TALYS 1.6 İki Bileşenli Eksiton ve Genelleştirilmiş Süperakışkan modelleri, EMPIRE 3.1 Eksiton ve Genelleştirilmiş Süperakışkan modelleri teorik hesaplamaları gerçekleştirmek için kullanılmıştır. Hesaplanan sonuçlar, Deneysel Nükleer Veri Kütüphanesi (EXFOR)'dan alınan deneysel sonuçlar ile karşılaştırılmıştır. 125I radyoizotopunun deneysel üretim tesir kesiti değerleri, deneysel zorluklardan dolayı üretilemiyorsa EMPIRE 3.1Eksiton ve Genelleştirilmiş Süperakışkan modelleri kullanılması önerilmiştir.

🔖

Cite This Article

Demir, B., Çapalı, V., Sarpün, İ., Kaplan, A. (2015). Production Cross–Section Calculations of Medical125I Radionuclide Using α, d and γ Induced Reactions. Süleyman Demirel Üniversitesi Fen Edebiyat Fakültesi Fen Dergisi, Volume: 10 Issue: 2. https://ajindex.com/articles/1277973

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Marchesi V., Gautier M., Villani N., Feuillade J.,Dejean C., 2013. Radionucleides, Technologies andq uality control in brachy therapy. Cancer/Radiothérapie. 17( 2): 85-88.
  2. Masucci G. L., Donath D., Tétreault-Laflamme A., Carrier J.F., Hervieux Y., Larouche R. X.,BaharyJ.P.,Taussky D., 2010. Comparison between high and low source activity seeds for I-125 permanent seed prostate brachytherapy, International Journal of Radiation Oncology Biology Physics, 78 (3): 781–786.
  3. Fontanesi J., Meyer D., Xu S., Tai D., 1993. Treatment of choroidal melanoma with I-125 plaque, International Journal of Radiation Oncology Biology Physics. 26 (4): 619-623.
  4. Qaim S.M., 2004. Use of cyclotrons in medicine, Radiation Physics and Chemistry, 71: 917–926.
  5. Zhuikov B.L., 2004.Production of medical radionuclides in Russia: Status and future—a review, Applied Radiation and Isotopes, 84: 48–56.
  6. Koning A., Hilaire S., Goriely S., 2013. TALYS–1.6 A Nuclear Reaction Program, User Manual (NRG, The Netherlands), First Edition: December, 23: 64–67.
  7. Herman M., Capote R., Carlson B. V., Obložinský P., Sin M., Trkov A.,Wienke H.,Zerkin, V., 2007. EMPIRE: Nuclear reaction model code system for data evaluation, Nuclear Data Sheets, 108 (12): 2655–2715.
  8. Cline C.K., 1972. The Pauli exclusion principle in pre-equilibrium decay, Nuclear Physics A, 195: 353-360.
  9. I. Ribansky et al., 1973, Pre-equilibrium decay and the exciton model, Nuclear Physics A, 205:545-560.
  10. Herman M., Capote R., Sin M., Trkov A., 2012.EMPIRE–3.1 Rivoli modular system for nuclear reaction calculations and nuclear data evaluation. User's Manual.
  11. Brookhaven National Laboratory, National Nuclear Data Center, EXFOR/CSISRS (Experimental Nuclear Reaction Data File). Database Version of August 20, 2014 (http://www.nndc.bnl.gov/exfor/) (2014)
  12. Veli Çapalı e-mail: [email protected]
  13. İsmail Hakkı Sarpün e-mail: [email protected]
  14. Abdullah Kaplan e-mail: [email protected]