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Journals / Gazi University Journal of Science / 2026 / Volume: 34 Issue: 2

Some Biological Activities of the Moss Brachythecium populeum (Hedw.) Bruch, Schimp. & W.Gumbel (Bryophyta)

Selda Kabadere(Eskişehir Osmangazi Üniversitesi Tıp Fakültesi)0000-0002-9589-0063
Filiz Birgi(Eskişehir Osmangazi Üniversitesi Fen-Edebiyat Fakültesi)0000-0003-4899-1723
Pınar Öztopçu Vatan(Eskişehir Osmangazi Üniversitesi Fen- Edebiyat Fakültesi)0000-0003-4339-4129
Cansu Fılık Iscen(Eskişehir Osmangazi Üniversitesi Eğitim Fakültesi)0000-0001-5463-8825
Semra İlhan(Eskişehir Osmangazi Üniversitesi Fen- Edebiyat Fakültesi)0000-0002-3787-2449
Pages
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Publication Date
2021-06-01
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Further studies are needed.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The present study assessed the antimicrobial and anticancer activities of Brachythecium populeum (Hedw.) Bruch, Schimp. & W.Gümbel (Brachytheciaceae) extracts using two different extracting methods.
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Key Findings & Data:Extract C has the highest effect against E. faecalis (13 mm), B. subtilis and S. aureus (12 mm).
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Conclusion & Impact:Further studies are needed.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Brachythecium populeum · Moss · Extract

Abstract

The present study assessed the antimicrobial and anticancer activities of Brachythecium populeum (Hedw.) Bruch, Schimp. & W.Gümbel (Brachytheciaceae) extracts using two different extracting methods. The antibacterial and antifungal activity of seven solvent extracts of Brachythecium populeum was examined against six species of bacteria and seven species of fungi by using well diffusion method. The minimal inhibitory concentration (MIC) of the extracts of acetone and C was determined. Extract C has the highest effect against E. faecalis (13 mm), B. subtilis and S. aureus (12 mm). The inhibition zone was showed by acetone extract against E. faecalis (13 mm), P. aeruginosa (10 mm) and B. subtilis (9 mm). Furthermore, all extracts exhibited different activities on P. aeruginosa. The MIC ranges acetone and C extracts against bacterial strains were from 93.8-375 μg/mL. Cytotoxic activities of extracts of acetone, A and C of B. populeum (0.17, 1.7, 17, 85 and 170 μg/mL) were tested against rat glioma cells by using MTT assay, after 24 and 48 h. Extracts of acetone, A and C showed a moderate toxicity, however high concentrations of extract A significantly decreased the survival of glioma cells in 48 h. The study confirms the antimicrobial and cytotoxic activities of B. populeum, extracted using various solvents. It is suggested that the active substances to be obtained by using different solvents from B. populeum may be the active substances of various drugs in the future. Further studies are needed.

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Cite This Article

Kabadere, S., Birgi, F., Vatan, P. Ö., Iscen, C. F., İlhan, S. (2021). Some Biological Activities of the Moss Brachythecium populeum (Hedw.) Bruch, Schimp. & W.Gumbel (Bryophyta). Gazi University Journal of Science, Volume: 34 Issue: 2. https://doi.org/10.35378/gujs.750754

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