SavedAdd your journal

Journals / Eurasian Journal of Medicine and Oncology / 2019 / Cilt: 3 - Sayı: 3

Dosimetric Comparison of Adjuvant Pelvic Radiotherapy for Endometrial Cancer using Intensity-Modulated Radiotherapy (IMRT), Volumetric Modulated Arc Therapy (VMAT) and Helical Tomotherapy (HT)

ÖZTUN TEMELLİ
Mehmet DEMİRTAŞ
Mahmut Serdar ŞİŞECİOĞLU
Eda Kaya PEPELE
Pages
203–210
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: It was found that the three techniques were suitable in terms of planning criteria and OARs.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: The purpose of the present study is to compare dosimetrically IMRT, VMAT, HT techniques in endometrium cancer adjuvant radiotherapy practice.
📊
Key Findings & Data:Methods: The 10 patients to whom we had applied Pelvic RT due to endometrium cancer previously were selected retrospectively.
💡
Conclusion & Impact:Conclusion: It was found that the three techniques were suitable in terms of planning criteria and OARs.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Objectives: The purpose of the present study is to compare dosimetrically IMRT, VMAT, HT techniques in endometrium cancer adjuvant radiotherapy practice. Methods: The 10 patients to whom we had applied Pelvic RT due to endometrium cancer previously were selected retrospectively. All patients had received TAH+BSO+BPLND. Three different plans were made for the patients as IMRT, VMAT, and HT. Results: The rectum V40 was found to be 53%, 54%, 45% (p=0.002), respectively; and the bladder V45 was 27%, 26%, 20% (p=0.002), respectively. Bowel V40 was found to be 15%,17%,12%, respectively (p=<0.001). Total monitor unit (MU) and beam-on times were found superior at VMAT (<0.001). Bone marrow V40 was found to be 27%, 26%, 33%, respectively (p<0.001). Conclusion: It was found that the three techniques were suitable in terms of planning criteria and OARs. HI and CI were found to be superior at HT. In risky organs, in rectum, bowel and bladder, HT was found to be superior than the others; in terms of bone marrow, IMRT was found to be superior; and in terms of bone, VMAT was found to be superior. VMAT has the advantage of having short treatment time and low MU.

🔖

Cite This Article

TEMELLİ, Ö., DEMİRTAŞ, M., ŞİŞECİOĞLU, M. S., PEPELE, E. K. (2019). Dosimetric Comparison of Adjuvant Pelvic Radiotherapy for Endometrial Cancer using Intensity-Modulated Radiotherapy (IMRT), Volumetric Modulated Arc Therapy (VMAT) and Helical Tomotherapy (HT). Eurasian Journal of Medicine and Oncology, Cilt: 3 - Sayı: 3, 203–210. https://ajindex.com/articles/125641

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. deHaydu C, Black JD, Schwab CL, English DP, Santin AD. An update on the current pharmacotherapy for endometrial cancer. Expert Opin Pharmacother 2016
  2. 489–99. 2. Safdieh J, Lee YC, Wong A, Lee A, Weiner JP, Schwartz D, et al. A Comparison of Outcomes Between Open Hysterectomy and Robotic-Assisted Hysterectomy for Endometrial Cancer Using the National Cancer Database. Int J Gynecol Cancer 2017
  3. 1508–16. 3. Keys HM, Roberts JA, Brunetto VL, Zaino RJ, Spirtos NM, Bloss JD, et al. A phase III trial of surgery with or without adjunctive external pelvic radiation therapy in intermediate risk endometrial adenocarcinoma: a Gynecologic Oncology Group study. Gynecol Oncol 2004
  4. Creutzberg CL, vanPutten WL, Koper PC, Lybeert ML, Jobsen JJ, Wárlám-Rodenhuis CC, et al. Surgery and postoperative radiotherapy versus surgery alone for patients with stage-1endometrial carcinoma: multicentre randomized trial. PORTEC Study Group. Post Operative Radiation Therapy in Endometrial Carcinoma. Lancet 2000
  5. 1404–11. 5. ASTEC/EN.5 Study Group, Blake P, Swart AM, Orton J, Kitchener H, Whelan T, et al. Adjuvant external beam radiotherapy in the treatment of endometrial cancer (MRC ASTEC and NCIC CTG EN.5 randomised trials): pooled trial results, systematic review and meta-analysis. Lancet 2009
  6. 137–46. 6. Mell LK, Mehrotra AK, Mundt AJ. Intensity-modulated radiation therapy use in the U.S., 2004. Cancer 2005
  7. 1296–303. 7. Mundt AJ, Lujan AE, Rotmensch J, Waggoner SE, Yamada SD, Fleming G, et al. Intensity-modulated whole pelvic radiotherapy in women with gynecologic malignancies. Int J Radiat Oncol Biol Phys 2002
  8. 1330–7. 8. Beriwal S, Jain SK, Heron DE, Kim H, Gerszten K, Edwards RP, et al. Clinical outcome with adjuvant treatment of endometrial carcinoma using intensity-modulated radiation therapy. Gynecol Oncol 2006
  9. 195–9. 9. Mundt AJ, Mell LK, Roeske JC. Preliminary analysis of chronic gastrointestinal toxicity in gynecology patients treated with intensity-modulated whole pelvic radiation therapy. Int J Radiat Oncol Biol Phys 2003
  10. 1354–60. 10. Jhingran A, Winter K, Portelance L, Miller B, Salehpour M, Gaur R, et al. A phase II study of intensity modulated radiation therapy to the pelvis for postoperative patients with endometrial carcinoma: radiation therapy oncology group trial 0418.Int J Radiat Oncol Biol Phys 2012
  11. e23–8. 11. Jia MX, Zhang X, Yin C, Feng G, Li N, Gao S, et al. Peripheral dose measurements in cervical cancer radiotherapy: a co