Journals / Eurasian Journal of Medicine and Oncology / 2020 / Cilt: 4 - Sayı: 1

First Case of Topical 5-FU Therapy for Cutaneous Metastasis in a Patient with Colon Cancer

Pages
89–93
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This treatment modality is easy to use and we would recommend clinical trials to be conducted to further study the use of topical 5-FU.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Cutaneous metastasis from colon cancer is rare, occurs in less than 6% of patients and its associated with poor prognosis.
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Key Findings & Data:We present a case of a 41-year-old female with colon cancer who developed cutaneous metastases to the scalp, and was treated with topical 5-FU and radiation therapy.
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Conclusion & Impact:This treatment modality is easy to use and we would recommend clinical trials to be conducted to further study the use of topical 5-FU.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Cutaneous metastasis from colon cancer is rare, occurs in less than 6% of patients and its associated with poor prognosis. Most often it presents in the abdomen, inguinal or perineal regions, supraclavicular area, and less commonly on the face, neck, scalp, and prior surgical sites. We present a case of a 41-year-old female with colon cancer who developed cutaneous metastases to the scalp, and was treated with topical 5-FU and radiation therapy. Treatment options for cutaneous metastases usually include systemic therapy, topical chemotherapy, surgical excision, or radiation. Our case is probably the first report who was treated with topical 5-FU in addition to radiation therapy. This treatment modality is easy to use and we would recommend clinical trials to be conducted to further study the use of topical 5-FU.

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Cite This Article

AHMED, G., VELASCO, S. A., DOREN, L. V., SAIF, M. W. (2020). First Case of Topical 5-FU Therapy for Cutaneous Metastasis in a Patient with Colon Cancer. Eurasian Journal of Medicine and Oncology, Cilt: 4 - Sayı: 1, 89–93. https://ajindex.com/articles/125452

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References (16)

  1. Qiu M, Hu J, Yang D, et al. Pattern of distant metastases in colorectal cancer: a SEER based study. Oncotarget 2015;17:38658–66
  2. A Amal, K Krishnaprasad, GP Praveen, V Shankar, N Keerthi N:A rare case of carcinoma rectum with scalp metastasis: an unusual presentation. Int Surg J 2018;5:1574–6
  3. Hashimi Y, S Dholakia. Facial cutaneous metastasis of colorectal adenocarcinoma. BMJ Case Rep 2013;1–3
  4. Nesseris I, Tsamakis C, Gregoriou S: Cutaneous metastasis of colon adenocarcinoma: case report and review of the literature. An Bras Dermatol 2013;88:56–8
  5. Wang DY, Ye F, Lin JJ, Xu X. Cutaneous metastasis: a rare phenomenon of colorectal cancer. Ann Surg Treat Res 2017;93:277–280
  6. Ha JY, Oh EH, Jung MK, Park SE, Kim JT, Hwang IG. Choroidal and skin metastases from colorectal cancer. World J Gastroenterol 2016;22:9650–3
  7. Horiuchi A, Nozawa K, Akahane T, Shimada R, Shibuya H, Aoyagi Y, et al. Skin metastasis from sigmoid colon cancer. Int Surg 2011;96:135–8
  8. Shah SR, Applebaum DS, Potenziani S, Huttenbach YT, Wolf J, Orengo IF. Cutaneous metastasis to the scalp as the primary presentation of colorectal adenocarcinoma. Dermatol Online J 2017;23:13030/qt31p698nz
  9. Reusser NM, Wu W, Mir M. Zosteriform metastasis of rectal adenocarcinoma: a case report. Dermatol Online J 2015;21:pii: 13030/qt0d5455rt
  10. Aravind B, Kumar R, Basnyat P. Cutaneous metastases secondary to colorectal carcinoma may not be as ominous as previously thought: a case report and review of the literature. BMJ Case Rep 2013;pii: bcr2013008556
  11. Góes HF, Lima Cdos S, Souza MB, Estrella RR, Faria MA, Rochael MC. Single cutaneous metastasis of colon adenocarcinoma - Case report. An Bras Dermatol 2016;91:517–9
  12. Udkoff J, Cohen PR. Adenocarcinoma of the colon presenting with scrotal metastasis: case report and review of the literature. Dermatology online journal 2016;22
  13. Dehal A, Patel S, Kim S, et al. Cutaneous Metastasis of Rectal Cancer: A Case Report and Literature Review. The Permanente journal 2016;20:74–8
  14. Reusser NM, Wu W, Mir M. Zosteriform metastasis of rectal adenocarcinoma: a case report. Dermatology online journal 2015;21
  15. Abt NB, Sampah MES, Boonyasai RT, et al. Primary colonic adenocarcinoma diagnosed with cutaneous shave biopsy. BMJ case reports 2015;2015:bcr2015210046
  16. Sheets N, Powers J, Richmond B. Cutaneous metastasis of colon cancer: case report and literature review. The West Virginia medical journal 2014;110:22–4. 17. de Miguel Valen