Journals / Eurasian Journal of Medicine and Oncology / 2020 / Cilt: 4 - Sayı: 1

Limb Salvage in Pediatrics with Malignant Bone Tumors: Team Approach to Orthopedic Oncology

Pages
26–34
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Improvements in biological reconstructive methods, as well as endoprosthetic design, allow effective limb-salvage choices after oncological resections in pediatrics that are ideally adjusted to the patient’s unique functional needs.

📌 3 Key Takeaways

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Objective & Hypothesis:Pediatric limb salvage necessitates collaboration of multi-disciplinary team approach; members are orthopedic oncologist, pediatric oncologist, radiologist, pathologist, physiotherapist, and psychotherapist.
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Key Findings & Data:Limb-salvage choices fall into two principal categories, biological reconstruction as well as endoprosthetic arthroplasty, each of which has functional and technical concerns that are fundamental to determine the optimal management option.
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Conclusion & Impact:Improvements in biological reconstructive methods, as well as endoprosthetic design, allow effective limb-salvage choices after oncological resections in pediatrics that are ideally adjusted to the patient’s unique functional needs.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

Pediatric limb salvage necessitates collaboration of multi-disciplinary team approach; members are orthopedic oncologist, pediatric oncologist, radiologist, pathologist, physiotherapist, and psychotherapist. Limb-salvage choices fall into two principal categories, biological reconstruction as well as endoprosthetic arthroplasty, each of which has functional and technical concerns that are fundamental to determine the optimal management option. Limb-salvage surgery in pediatrics has unique challenges, with precise planning to assure the maintenance of limb-length equality with durable construction for long-term function into adulthood. Limb salvage can achieve satisfactory oncological and functional results and quality of life as compared with amputation. Improvements in biological reconstructive methods, as well as endoprosthetic design, allow effective limb-salvage choices after oncological resections in pediatrics that are ideally adjusted to the patient’s unique functional needs.

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Cite This Article

HASAN, B. Z., MESREGAH, M. K. (2020). Limb Salvage in Pediatrics with Malignant Bone Tumors: Team Approach to Orthopedic Oncology. Eurasian Journal of Medicine and Oncology, Cilt: 4 - Sayı: 1, 26–34. https://ajindex.com/articles/124579

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References (16)

  1. Cortes EP, Holland JF, Wang JJ, Sinks LF, Blom J, Senn H, et al. Amputation and adriamycin in primary osteosarcoma. N Engl J Med 1974;291:998–1000
  2. Woodruff M. The challenge of osteosarcoma. Ann R Coll Surg Engl 1969;44:299–307
  3. Campanacci M, Laus M. Local recurrence after amputation for osteosarcoma. J Bone Joint Surg Br 1980;62-b:201–7
  4. Price CH, Zhuber K, Salzer-Kuntschik M, Salzer M, Willert HG, Immenkamp M, et al. Osteosarcoma in children. A study of 125 cases. J Bone Joint Surg Br 1975;57:341–5
  5. Campanacci M, Cervellati G. Osteosarcoma: A review of 345 cases. Ital J Orthop Traumatol 1975;1:5–22
  6. Sinks LF, Mindell ER. Chemotherapy of osteosarcoma. Clin Orthop Relat Res 1975:101–4
  7. Jaffe N. The potential for an improved prognosis with chemotherapy in osteogenic sarcoma. Clin Orthop Relat Res 1975:111–8. 8. van Oosterwijk JG, Anninga JK, Gelderblom H, Cleton-Jansen AM, Bovee JV. Update on targets and novel treatment options for high-grade osteosarcoma and chondrosarcoma. Hematol Oncol Clin North Am 2013;27:1021–48
  8. Cohen IJ, Kaplinsky C, Katz K, Mor C, Goshen Y, Yaniv Y, et al. Improved results in osteogenic sarcoma 1973-79 vs. 1980- 86: analysis of results from a single center. Isr J Med Sci 1993;29:27–9
  9. Simon MA, Aschliman MA, Thomas N, Mankin HJ. Limb-salvage treatment versus amputation for osteosarcoma of the distal end of the femur. J Bone Joint Surg Am 1986;68:1331–7
  10. Eilber FR, Mirra JJ, Grant TT, Weisenburger T, Morton DL. Is amputation necessary for sarcomas? A seven-year experience with limb salvage. Ann Surg 1980;192:431–8
  11. Rougraff BT, Simon MA, Kneisl JS, Greenberg DB, Mankin HJ. Limb salvage compared with amputation for osteosarcoma of the distal end of the femur. A long-term oncological, functional, and quality-of-life study. J Bone Joint Surg Am 1994;76:649–56
  12. Choong PF, Sim FH. Limb-sparing surgery for bone tumors: new developments. Semin Surg Oncol 1997;13:64–9
  13. Carty CP, Bennett MB, Dickinson IC, Steadman P. Assessment of kinematic and kinetic patterns following limb salvage procedures for bone sarcoma. Gait Posture 2009;30:547–51
  14. DiCaprio MR, Friedlaender GE. Malignant bone tumors: limb sparing versus amputation. J Am Acad Orthop Surg 2003;11:25–37
  15. Zahlten-Hinguranage A, Bernd L, Ewerbeck V, Sabo D. Equal quality of life after limb-sparing or ablative surgery for lower extremity sarcomas. Br J Cancer 2004;91:1012–4
  16. Ottaviani G, Robert RS, Huh WW, Palla S, Jaffe N. Sociooccu