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Journals / Journal of Istanbul Veterinary Sciences / 2026 / Cilt: 9 Sayı: 1

Evaluation of Canine parvovirus – 2 case observed in a Toy Poodle breed dog

Toy Poodle Irkı Köpekte Görülen Canine Parvo Virus – 2 Olgusunun Değerlendirilmesi

Rüveyde Gülbahçe(SELCUK UNIVERSITY)0000-0002-3665-4642
Hasan Sercan Palancı(SELCUK UNIVERSITY)0000-0001-5408-9176
Irmak Dik(SELCUK UNIVERSITY)0000-0003-2516-9489
Tuğçe Baş(SELCUK UNIVERSITY)0000-0002-7118-0235
Oya Bulut(DOKUZ EYLUL UNIVERSITY)0000-0002-2407-7390
Pages
23–29
Publication Date
2025-04-30
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This study underscores CPV-2 infection risks in vaccinated populations, highlighting the significance of monitoring VP2 region nucleotide changes and antigenic variants to ensure vaccine efficacy and effective disease control.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Canine parvovirus (CPV-2) is a severe disease in puppies, characterized by high morbidity and mortality, often causing hemorrhagic enteritis and death.
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Key Findings & Data:The dog was clinically diagnosed with CPV-2, and PCR analysis of blood and fecal samples at the Department of Virology, Faculty of Veterinary Medicine, Selcuk University, confirmed viral DNA presence.
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Conclusion & Impact:This study underscores CPV-2 infection risks in vaccinated populations, highlighting the significance of monitoring VP2 region nucleotide changes and antigenic variants to ensure vaccine efficacy and effective disease control.
🔬Design:Olgu Sunumu
📍Scope:Comprehensive Sample
⚙️Variables:Canine parvovirus · olgu sunumu · viral enteritler

Abstract

Canine parvovirus (CPV-2) is a severe disease in puppies, characterized by high morbidity and mortality, often causing hemorrhagic enteritis and death. This case involved a three-month-old female toy poodle brought to the clinic with anorexia, diarrhea, lethargy, and vomiting. The dog was clinically diagnosed with CPV-2, and PCR analysis of blood and fecal samples at the Department of Virology, Faculty of Veterinary Medicine, Selcuk University, confirmed viral DNA presence. After treatment, the dog fully recovered. This study underscores CPV-2 infection risks in vaccinated populations, highlighting the significance of monitoring VP2 region nucleotide changes and antigenic variants to ensure vaccine efficacy and effective disease control.

Özet

Canine parvovirus (CPV-2), genellikle hemorajik enterite ve ölüme neden olan, yüksek morbidite ve mortalite ile karakterize şiddetli bir hastalıktır ve özellikle yavru köpeklerde görülür. Bu vaka, anoreksi, letarji ve kusma şikayetleri ile kliniğe getirilen üç aylık dişi bir toy poodle'ı içermektedir. Köpek, klinik olarak CPV-2 teşhisi almış ve Selçuk Üniversitesi Veteriner Fakültesi, Viroloji Anabilim Dalı'nda kan ve dışkı örneklerine yapılan PCR analizi, viral DNA varlığını doğrulamıştır. Tedavi sonrası köpek tamamen iyileşmiştir. Bu çalışma, aşılı popülasyonlarda CPV-2 enfeksiyon risklerini vurgulayarak, VP2 bölgesindeki nükleotid değişiklikleri ve antijenik varyantların izlenmesinin, aşının etkinliğini ve etkili hastalık kontrolünü sağlamak açısından önemine dikkat çekmektedir.

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Cite This Article

Gülbahçe, R., Palancı, H. S., Dik, I., Baş, T., Bulut, O. (2025). Evaluation of Canine parvovirus – 2 case observed in a Toy Poodle breed dog. Journal of Istanbul Veterinary Sciences, Cilt: 9 Sayı: 1, 23–29. https://doi.org/10.30704/http-www-jivs-net.1600129

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References (19)

  1. Abayli, H., Aslan, O., Tumer, K.C., Sahna, K.C., & Tonbak, S. (2022). Predominance and first complete genomic characterization of canine parvovirus 2b in Turkey. Archives of Virology, 167,1831-1840.
  2. Castro, T. X., Rita de Cássia, N., Gonçalves, L.P., Costa, E.M., Marcello, G.C., Labarthe, N.V., & Mendes de Almeida, F. (2013). Clinical, hematological, and biochemical findings in puppies with coronavirus and parvovirus enteritis. The Canadian Veterinary Journal, 54 (9), 885.
  3. de Oliveira, P.S.B., Cargnelutti, J.F., Masuda, E.K., Weiblen, R., & Flores, E.F. (2019). New variants of canine parvovirus in dogs in southern. Brazilian Archives of Biology and Technology, 164, 1361-1369.
  4. Decaro, N., & Buonavoglia, C. (2012). Canine parvovirus—a review of epidemiological and diagnostic aspects, with emphasis on type 2c. Veterinary Microbiology, 155, 1-12.
  5. Decaro, N., Buonavoglia, C., & Barrs, V. (2020). Canine parvovirus vaccination and immunisation failures: Are we far from disease eradication?. Veterinary Microbiology, 247, 108760.
  6. Decaro, N., Crescenzo, G., Desario, C., Cavalli, A., Losurdo, M., Colaianni, M.L., Ventrella, G., Rizzi, S., Aulicino, S., Lucente, M.S., & Buonavoglia, C. (2014). Long-term viremia and fecal shedding in pups after modified-live canine parvovirus vaccination. Vaccine, 32 (30), 3850-3853.
  7. Decaro, N., Desario, C., Elia, G., Campolo, M., Lorusso, A., Mari, V., Martella, V., & Buonavoglia, C. (2007). Occurrence of severe gastroenteritis in pups after canine parvovirus vaccine administration: a clinical and laboratory diagnostic dilemma. Vaccine. 25(7):1161-6.
  8. Dik, I., & Şimşek, A. (2021). Comparison of different diagnostic methods in detection of canine parvovirus infection. Eurasian Journal of Veterinary Sciences, 37, 76-81.
  9. Freisl, M., Speck, S., Truyen, U., Reese, S., Proksch, A.L., & Hartmann, K. (2017). Faecal shedding of canine parvovirus after modified-live vaccination in healthy adult dogs. The Veterinary Journal, 219, 15-21.
  10. Hasib, F.Y., Akter, S., & Chowdhury, S. (2021). First report of canine parvovirus molecular detection in Bangladesh. Veterinary World, 14, 10-38.
  11. Headley, S.A., Alfieri, A.A., Fritzen, J.T., Garcia, J.L., Weissenböck, H., da Silva, A.P., Bodnar, L., Okano, W., & Alfieri, A.F (2013). Concomitant canine distemper, infectious canine hepatitis, canine parvoviral enteritis, canine infectious tracheobronchitis, and toxoplasmosis in a puppy. Journal of Veterinary Diagnostic Investigation, 25 (1), 129-35.
  12. Hoang, M., Lin, W.H., Le, V.P., Nga, B.T.T., Chiou, M.T., & Lin, C.N. (2019). Molecular epidemiology of canine parvovirus type 2 in Vietnam from November 2016 to February 2018. Virology Journal, 16, 1-11.
  13. Lin, I.Y., Van, T.T.H., & Smooker, P.M. (2015). Live-attenuated bacterial vectors: tools for vaccine and therapeutic agent delivery. Vaccines, 3(4), 940-972.
  14. Mila, H., Grellet, A., Desario, C., Feugier, A., Decaro, N., Buonavoglia, C., & Chastant-Maillard, S. (2014). Protection against canine parvovirus type 2 infection in puppies by colostrum-derived antibodies. Journal of Nutritional Science, 3, e54.
  15. Mohr, A.J., Leisewitz, A.L., Jacobson, L.S., Steiner, J.M., Ruaux, C.G., & Williams, D.A. (2003). Effect of early enteral nutrition on intestinal permeability, intestinal protein loss, and outcome in dogs with severe parvoviral enteritis. Journal of Veterinary Internal Medicine, 17, 791-798.
  16. Mylonakis, M.E., Kalli, I., & Rallis, T.S. (2016). Canine parvoviral enteritis: an update on the clinical diagnosis, treatment, and prevention. Veterinary Sciences: Research and Reviews, 7, 91.
  17. Nandi, S., & Kumar, M. (2010). Canine parvovirus: current perspective. Indian Journal of Virology, 21, 31-44.
  18. Waner, T., Naveh, A., Wudovsky, I., & Carmichael, L.E. (1996). Assessment of maternal antibody decay and response to canine parvovirus vaccination using a clinic-based enzyme-linked immunosorbent assay. Journal of Veterinary Diagnostic Investigation, 8, 427-432.
  19. Wu, H., Li, X., Wang, L., Liu, Y., & Tian, K. (2018). Molecular epidemiological survey of canine parvovirus in domestic dogs in four provinces, China. Virus Disease, 29, 113-117.