Journals / Sağlık Bilimlerinde İleri Araştırmalar Dergisi / 2026 / Volume: 8 Issue: 1

ARRHYTHMIAS DEVELOPING DURING ACUTE RHEUMATIC FEVER: A LONG-TERM SINGLE CENTRE EXPERIENCE

Serra Karaca(İstanbul University, İstanbul Faculty of Medicine, Division of Pediatric Cardiology)0000-0001-5421-0191
Kemal Nişli(İstanbul University, İstanbul Faculty of Medicine, Division of Pediatric Cardiology)0000-0001-9085-9852
Pages
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Publication Date
2025-03-04
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Further research is needed to elucidate the underlying mechanisms and optimise treatment strategies for arrhythmias in ARF.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: This study aimed to evaluate the prevalence, types, and clinical significance of arrhythmias observed during acute rheumatic fever (ARF) episodes and their association with the severity of carditis in a single centre paediatric cohort.
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Key Findings & Data:Material and Methods: A retrospective review of medical records from 118 patients diagnosed with ARF based on the revised Jones criteria was performed.
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Conclusion & Impact:Further research is needed to elucidate the underlying mechanisms and optimise treatment strategies for arrhythmias in ARF.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Rheumatic fever · arrhythmia · carditis

Abstract

Objective: This study aimed to evaluate the prevalence, types, and clinical significance of arrhythmias observed during acute rheumatic fever (ARF) episodes and their association with the severity of carditis in a single centre paediatric cohort. Material and Methods: A retrospective review of medical records from 118 patients diagnosed with ARF based on the revised Jones criteria was performed. Electrocardiograms (ECGs) recorded during the acute phase were analysed for arrhythmias, including atrioventricular (AV) blocks, supraventricular and ventricular arrhythmias, and conduction disturbances. Patients were stratified into mild-moderate and severe carditis groups. Statistical analyses were conducted using SPSS 26.0, with p-values<0.05 considered significant. Results: Among the 118 patients (mean age 10.5±1.7 years; 55% female), 51.6% exhibited first-degree AV block. The other arrhythmias included second-degree AV block (4.2%), complete AV block (0.8%), supraventricular tachycardia (0.8%), non-sustained ventricular tachycardia (0.8%), and junctional rhythm (1.7%). Supraventricular and ventricular extrasystoles were identified in 4.2% and 5.9% of the patients, respectively. Most arrhythmias occurred in the mild-to-moderate carditis group and resolved spontaneously or with minimal intervention. No arrhythmias were associated with mortality or long-term complications. Conclusion: Arrhythmias during ARF are relatively uncommon but may reflect myocardial inflammation. While typically benign and self-limiting, vigilant monitoring is essential for timely management. Further research is needed to elucidate the underlying mechanisms and optimise treatment strategies for arrhythmias in ARF.

Özet

Amaç: Bu çalışma, akut romatizmal ateş (ARA) sırasında gelişen aritmilerin prevalansını, türlerini ve klinik önemini değerlendirmeyi ve bu aritmilerin kardit şiddetiyle ilişkisini incelemeyi amaçlamaktadır. Gereç ve Yöntemler: Revize edilmiş Jones kriterlerine göre ARA tanısı konulan 118 hastanın tıbbi kayıtları retrospektif olarak incelendi. Akut dönemde kaydedilen elektrokardiyogramlar (EKG) atriyoventriküler (AV) bloklar, supraventriküler ve ventriküler aritmiler ile iletim bozuklukları açısından değerlendirildi. Hastalar hafif-orta ve şiddetli kardit gruplarına ayrıldı. İstatistiksel analizler SPSS 26.0 kullanılarak yapıldı ve p < 0.05 anlamlı kabul edildi. Bulgular: Çalışmaya dahil edilen 118 hastanın (ortalama yaş 10,5±1,7 yıl; %55’i kız) %51,6’sında birinci derece AV blok tespit edildi. Diğer aritmiler arasında ikinci derece AV blok (%4,2), tam AV blok (%0,8), supraventriküler taşikardi (%0,8), “non-sustained” ventriküler taşikardi (%0,8) ve “junctio nal” ritim (%1,7) yer aldı. Supraventriküler ve ventriküler ekstrasistol ise sırasıyla %4,2 ve %5,9 hastada saptandı. Aritmilerin büyük çoğunluğu hafif-orta kardit grubunda görüldü ve genellikle spontan olarak veya mini mal müdahale ile düzeldi. Aritmilere bağlı ölüm veya uzun dönem kompli kasyon bildirilmedi. Sonuç: ARA sırasında gelişen aritmiler nadir görülmekle birlikte, miyokar diyal inflamasyonu yansıtabilir. Genellikle iyi huylu ve kendiliğinden düze len bu durumların zamanında tanınması ve izlenmesi önemlidir. ARA’da aritmilerin altında yatan mekanizmaların ve tedavi yaklaşımlarının optimi ze edilmesi için daha fazla araştırmaya ihtiyaç vardır.

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Cite This Article

Karaca, S., Nişli, K. (2025). ARRHYTHMIAS DEVELOPING DURING ACUTE RHEUMATIC FEVER: A LONG-TERM SINGLE CENTRE EXPERIENCE. Sağlık Bilimlerinde İleri Araştırmalar Dergisi, Volume: 8 Issue: 1. https://doi.org/10.26650/JARHS2025-1623143

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