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Journals / Türk Spor ve Egzersiz Dergisi / 2019 / Cilt: 21 Sayı: 1

Effect of l-carnıtıne used ın regular exercıse ın elderly obesıs rats

İbrahim Kubilay Türkay(MEHMET AKIF ERSOY UNIVERSITY)
Aynur Başalp(MEHMET AKIF ERSOY UNIVERSITY)
Pages
74–77
Publication Date
2019-04-30
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

At the end of the study, it was determined that the weight of the old obese rats who used L-Carnitine together with the regular exercise for 12 weeks, both on the 45th and 90th days, was found.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The aim of this study was to investigate the effect of L-Caritine supplemented elderly rats on weight loss during 12 weeks.
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Key Findings & Data:In this study, 8 obese aged rats were used for 20 months.
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Conclusion & Impact:At the end of the study, it was determined that the weight of the old obese rats who used L-Carnitine together with the regular exercise for 12 weeks, both on the 45th and 90th days, was found.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:Elderly obese · Rat · Regular exercise

Abstract

The aim of this study was to investigate the effect of L-Caritine supplemented elderly rats on weight loss during 12 weeks. This experimental study was carried out on experimental animals in a scientific laboratory environment, under defined conditions and according to the method of application. Therefore, the model of the research is an experimental research model. In this study, 8 obese aged rats were used for 20 months. Approximately 70 years of human life is equivalent. The rats were given special cholesterol food for obesity. In the study, L-Carnitine was administered to the experimental group 3 times a week just before the exercise, with the daily dose of the sublingual fluid administered to the rats in a suitable dose (1 gr./kg). Before the exercise + L-Carnitine application, weight measurements of the rats were recorded at the beginning of the study (day 1), in the middle of the study (day 45) and finally at the end of the study (day 90). The “IBM SPSS Statistics 22 analiz package program was used to evaluate the statistical analysis of the study. Normal distribution assumptions were evaluated with Kolmogorov-Smirnov and Shapiro-Wilk tests. In the rare cases where the two tests are contradictory, the Kolmogorov-Smirnov test result, which is more preferred in small data sets, was used. Type 1 error margin for normality tests is taken as 0.05. At the end of the study, it was determined that the weight of the old obese rats who used L-Carnitine together with the regular exercise for 12 weeks, both on the 45th and 90th days, was found.

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Cite This Article

Türkay, İ. K., Başalp, A., *, İ. K. T. (2019). Effect of l-carnıtıne used ın regular exercıse ın elderly obesıs rats. Türk Spor ve Egzersiz Dergisi, Cilt: 21 Sayı: 1, 74–77. https://doi.org/10.15314/tsed.552115

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References (14)

  1. Adams, S. H., Hoppel, C. L., Lok, K. H., Zhao, L., Wong, S. W., et al. (2009). Plasma acylcarnitine profiles suggest incomplete long‐chain fatty acid beta‐oxidation and altered tricarboxylic acid cycle activity in type 2 diabetic African‐American women. J. Nutr. 139, 1073–1081.
  2. Artıs, A.S. (2009). The Relationship Between Proinflammatory Cytokines and Brain Natriuretic Peptide (Bnp) Level in Acute Intensive Exercise, (Unpublished Specialization Thesis), Erciyes University Faculty of Medicine, Department of Physiology, Kayseri, Turkey; 3, 5, 16, 17, 60.
  3. Brownell, KD., Wadden, TA. (1992). Etiology and treatment of obesity: Towards understanding a serious, prevalent and refractory disorder. J Consult Clin Psychol, 60: 505-17.
  4. Halliwell, B. (2001). Free radicals and other reactive species in disease. In: Encyclopedia of life sciences. Ed: J. Wiley & Sons; London: Nature Publishing Group; 1-7.
  5. Hoppel, C. L., and Genuth, S. M. (1980) Carnitine metabolism in normal‐weight and obese human subjects during fasting. Am. J. Physiol. 238, E409–E415.
  6. Hoppel, C. L., and Genuth, S. M. (1982). Urinary excretion of acetylcarnitine during human diabetic and fasting ketosis. Am. J. Physiol. 243, E168–E172.
  7. Lee, B. J., Lin, J. S., Lin, Y. C. & Lin, P. T. (2016). Effects of l‐carnitine supplementation on lipid profiles in patients with coronary artery disease. Lipids Health Dis. 15, 107.
  8. Lindeboom, L., Nabuurs, C. I., Hoeks, J., Brouwers, B., Phielix, E. & al. (2014). Long‐echo time MR spectroscopy for skeletal muscle acetylcarnitine detection. J. Clin. Invest. 124, 4915–4925.
  9. Odland, L. M., Heigenhauser, G. J., Wong, D., Hollidge‐Horvat, M. G. & Spriet, L. L. (1998). Effects of increased fat availability on fat‐carbohydrate interaction during prolonged exercise in men. Am. J. Physiol. 274, R894–R902.
  10. Roepstorff, C., Halberg, N., Hillig, T., Saha, A. K., Ruderman, N. B. & al. (2005). Malonyl‐CoA and carnitine in regulation of fat oxidation in human skeletal muscle during exercise. Am. J. Physiol. Endocrinol. Metab. 288, E133–E142.
  11. Saygın, O. (2003). Investigation of Physical Activity Levels and Physical Fitness of 10. 12 Years Old Children. Sıpirdusa: PhD Thesis. Marmara University, Institute of Health Sciences.
  12. Stone, M.H. (1994). Eating Disorders. Essentials of Strength Training and Contitioning. (Ed. Baechle TR). Canada: Human Kinetics. 238–239.
  13. Yaprak, Y. (2004). Effects of Aerobic and Strength Study on Oxygen Use and Cardiac Flow in Obese Women. Journal of Physical Education and Sport Sciences. II (2): 73-80.
  14. Zhao, G., Zhou, S., Davie, A. & Su, Q. (2012). Effects of moderate and high intensity exercise on T1/T2 balance. Exerc. Immunol. Rev. 18, 98–114.