SavedAdd your journal

Journals / Turkish Journal of Veterinary and Animal Sciences / 2008 / Cilt: 32 - Sayı: 4

Associations between GHR and IGF-1 Gene Polymorphisms, and Reproductive Traits in Wenchang Chickens

Hui-fang LI
Wen-qi ZHU
Kuan-wei CHEN
Xu WU
Qing-ping TANG
Yu-shi GAO
Pages
281–285
Publication Date
2008-04-01
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The current research supports the effects of GHR and IGF-1 genes on the reproductive traits of chickens.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Alleles of physiological candidate genes for reproductive traits, insulin-like growth factor-1 (IGF-1), and growth hormone receptor (GHR) were assessed to determine their associations with total egg production (NE), average days of continual egg-laying (ADCE), and number of double yolk eggs (DYE) in Wenchang chickens (Chinese indigenous breed).
📊
Key Findings & Data:The frequency of restriction enzyme C1/C2 alleles in the population was 0.53 (C1) and 0.47 (C2) for IGF-1.
💡
Conclusion & Impact:The current research supports the effects of GHR and IGF-1 genes on the reproductive traits of chickens.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Chicken · IGF-1 · GHR

Abstract

Alleles of physiological candidate genes for reproductive traits, insulin-like growth factor-1 (IGF-1), and growth hormone receptor (GHR) were assessed to determine their associations with total egg production (NE), average days of continual egg-laying (ADCE), and number of double yolk eggs (DYE) in Wenchang chickens (Chinese indigenous breed). PCR-RFLP was used for genotype identification. The frequency of restriction enzyme C1/C2 alleles in the population was 0.53 (C1) and 0.47 (C2) for IGF-1. For GHR-intron 2 it was 0.06 and 0.94 for (A1) and (A2), respectively, while for GHR-intron 5 it was 0.20 (B1) and 0.80 (B2). Four significant associations were found (P < 0.05): between IGF-1 polymorphism, and NE (300 d), NE (400 d), and ADCE, and between GHR polymorphism and DYE. Two significant effects were observed: for IGF-1 and NE (300 d), and for GHR intron 2 and DYE. The current research supports the effects of GHR and IGF-1 genes on the reproductive traits of chickens.

Özet

Alleles of physiological candidate genes for reproductive traits, insulin-like growth factor-1 (IGF-1), and growth hormone receptor (GHR) were assessed to determine their associations with total egg production (NE), average days of continual egg-laying (ADCE), and number of double yolk eggs (DYE) in Wenchang chickens (Chinese indigenous breed). PCR-RFLP was used for genotype identification. The frequency of restriction enzyme C1/C2 alleles in the population was 0.53 (C1) and 0.47 (C2) for IGF-1. For GHR-intron 2 it was 0.06 and 0.94 for (A1) and (A2), respectively, while for GHR-intron 5 it was 0.20 (B1) and 0.80 (B2). Four significant associations were found (P < 0.05): between IGF-1 polymorphism, and NE (300 d), NE (400 d), and ADCE, and between GHR polymorphism and DYE. Two significant effects were observed: for IGF-1 and NE (300 d), and for GHR intron 2 and DYE. The current research supports the effects of GHR and IGF-1 genes on the reproductive traits of chickens.

🔖

Cite This Article

LI, H., ZHU, W., CHEN, K., WU, X., TANG, Q., GAO, Y. (2008). Associations between GHR and IGF-1 Gene Polymorphisms, and Reproductive Traits in Wenchang Chickens. Turkish Journal of Veterinary and Animal Sciences, Cilt: 32 - Sayı: 4, 281–285. https://ajindex.com/articles/122450

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (10)

  1. Beccavin, C., Chevalier, B., Cogburn, L.A., Simon, J., Duclos, M.J.: Insulin-like growth factors and body growth in chickens divergently selected for high or low growth rate. J. Endocrinol., 2001; 168: 297-306.
  2. King, J.C.: Physiology of pregnancy and nutrient metabolism, Am. J. Clin. Nutr., 2000; 71: 1218-1225.
  3. Harvey, S., Hull, K.L.: Growth hormone. A paracrine growth factor? Endocrine, 1997; 7: 267-279.
  4. Hocking, P.M., Bernard, R., Wilkie, R.S., Goddard, C.: Plasma growth hormone and insulin-like growth factor-1 (IGF-1) concentrations at the onset of lay in ad libitum and restricted broiler breeder fowl. Br. Poult. Sci., 1994; 35: 299-308.
  5. Feng, X.P, Kuhnlein, U., Fairfull, W.R, Aggrey, S.E, Yao, J., Zadworny, D.: A genetic marker in the growth hormone receptor gene associated with body weight in chickens. J. Hered.,1998; 89: 355-359.
  6. Kuhnlein, U., Ni, L., Weigend, S, Gavora, J.S, Fairfull, W., Zadworny, D.: DNA polymorphisms in the chicken growth hormone gene: response to selection for disease resistance and association with egg production. Anim. Genet., 1997; 28: 116- 123. National Research Council: Nutrient Requirements of Poultry. National Academy Press,
  7. Washington, DC. 1994.
  8. Dunn, I.C, Miao, Y.W., Morris, A., Romanov, M.N., Wilson, P.W., Waddington, D.: A study of association between genetic markers in candidate genes and reproductive traits in one generation of a commercial broiler breeder hen population. Heredity, 2004; 92: 128-134.
  9. Bruggeman, V., Vanmontfort, D., Renaville, R., Portetelle, D., Decuypere, E.: The effect of food intake from two weeks of age to sexual maturity on plasma growth hormone, insulin-like growth factor-1, insulin-like growth factor-binding proteins and thyroid hormones in female broiler breeder chickens. Gen. Comp. Endocrinol., 1997; 107: 212-220.
  10. Decuypere, E., Huybrechts, L.M., Kühn, E.R., Tixier-Boichard, M., Mérat, P.: Physiological alterations associated with the chicken sex-linked dwarfing gene. Crit. Rev. Poult. Biol., 1991; 3: 191- 221. Williams, J., Sharp, P.J., Goddard, C.: The effects of growth hormone on ovarian follicular growth in the domestic hen. J. Reprod. Fertil. Abstr. Ser., 1992; 9: 59.