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Journals / Turkish Journal of Veterinary and Animal Sciences / 2013 / Cilt: 37 - Sayı: 3

Indel mutation of the ADD1/SREBP-1c gene in the South Anatolian Red and East Anatolian Red cattle breeds

Kemal Özdem ÖZTABAK
İraz Akiş AKAD
Feraye Esen GÜRSEL*
Atila ATEŞ
Pages
255–258
Publication Date
2013-03-01
DOI
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⚡ TL;DR(Too Long; Didn't Read)

As a result, we can conclude that determination of ADD1/SREBP1c genotype distribution in a great number of cattle breeds of Bos taurus and Bos indicus would allow us to observe more SS genotypes.

📌 3 Key Takeaways

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Objective & Hypothesis:The present study was designed to determine genotypes of adipocyte determination and differentiation-dependent factor 1 (ADD1)/sterol regulatory element-binding protein-1c (SREBP1c) in South Anatolian Red (SAR) and East Anatolian Red (EAR) cattle.
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Key Findings & Data:Fifty cattle from the SAR breed and 43 cattle from the EAR breed were used.
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Conclusion & Impact:As a result, we can conclude that determination of ADD1/SREBP1c genotype distribution in a great number of cattle breeds of Bos taurus and Bos indicus would allow us to observe more SS genotypes.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Key words: Native Turkish cattle · PCR · indel mutation

Abstract

The present study was designed to determine genotypes of adipocyte determination and differentiation-dependent factor 1 (ADD1)/sterol regulatory element-binding protein-1c (SREBP1c) in South Anatolian Red (SAR) and East Anatolian Red (EAR) cattle. Fifty cattle from the SAR breed and 43 cattle from the EAR breed were used. Intron 7 of the ADD1/SREBP1c gene containing an 84 bp indel mutation was amplified by polymerase chain reaction (PCR). The number of SS genotyped individuals with the 84 bp deletion associated with fatty acid composition and growth traits were very low in both breeds. The frequency of the LL genotype with the 84 bp insertion was significantly higher. The 2 cattle populations were in Hardy-Weinberg equilibrium. The SS genotype was observed in the SAR and EAR breeds. As a result, we can conclude that determination of ADD1/SREBP1c genotype distribution in a great number of cattle breeds of Bos taurus and Bos indicus would allow us to observe more SS genotypes.

Özet

The present study was designed to determine genotypes of adipocyte determination and differentiation-dependent factor 1 (ADD1)/sterol regulatory element-binding protein-1c (SREBP1c) in South Anatolian Red (SAR) and East Anatolian Red (EAR) cattle. Fifty cattle from the SAR breed and 43 cattle from the EAR breed were used. Intron 7 of the ADD1/SREBP1c gene containing an 84 bp indel mutation was amplified by polymerase chain reaction (PCR). The number of SS genotyped individuals with the 84 bp deletion associated with fatty acid composition and growth traits were very low in both breeds. The frequency of the LL genotype with the 84 bp insertion was significantly higher. The 2 cattle populations were in Hardy-Weinberg equilibrium. The SS genotype was observed in the SAR and EAR breeds. As a result, we can conclude that determination of ADD1/SREBP1c genotype distribution in a great number of cattle breeds of Bos taurus and Bos indicus would allow us to observe more SS genotypes.

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Cite This Article

ÖZTABAK, K. Ö., AKAD, İ. A., GÜRSEL*, F. E., ATEŞ, A. (2013). Indel mutation of the ADD1/SREBP-1c gene in the South Anatolian Red and East Anatolian Red cattle breeds. Turkish Journal of Veterinary and Animal Sciences, Cilt: 37 - Sayı: 3, 255–258. https://ajindex.com/articles/121776

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