Journals / Turkish Journal of Veterinary and Animal Sciences / 2012 / Cilt: 36 - Sayı: 6

The effect of intrauterine cephapirin treatment after insemination on conception rate in repeat breeder dairy cows subjected to the progesterone-based Ovsynch protocol

Pages
622–627
Publication Date
2012-06-01
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Thus, post-TAI intrauterine cephapirin administration was not found to be useful for the treatment of potential subclinical endometritis in repeat breeder dairy cows.

📌 3 Key Takeaways

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Objective & Hypothesis:Subclinical endometritis contributes to repeat breeder syndrome in dairy cows.
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Key Findings & Data:This study evaluated the effect of intrauterine cephapirin benzathine administration after timed artificial insemination (TAI) on the conception rate (CR) in repeat breeder dairy cows.
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Conclusion & Impact:Thus, post-TAI intrauterine cephapirin administration was not found to be useful for the treatment of potential subclinical endometritis in repeat breeder dairy cows.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Key words: Repeat breeder · conception rate · endometritis

Abstract

Subclinical endometritis contributes to repeat breeder syndrome in dairy cows. This study evaluated the effect of intrauterine cephapirin benzathine administration after timed artificial insemination (TAI) on the conception rate (CR) in repeat breeder dairy cows. To determine the antibiotic effects, all cows (n = 335) that had more than 3 services with no clinical abnormalities of the reproductive tract received the same combined synchronisation protocol: an ear implant containing progestagen using the Ovsynch protocol and a third gonadotropin-releasing hormone (GnRH) administration 7 days after TAI. Cows in the treatment group (TRT; n = 160) received intrauterine cephapirin 12 h after TAI, and cows in the control group (CON; n = 175) did not receive intrauterine antibiotics. The percentage of cows that responded to the first (67.5% in TRT, 70.9% in CON) and second (98.8% in TRT, 97.1% in CON) GnRH of Ovsynch was similar between the groups. In addition, the response to the third GnRH administration after TAI (88.1% in TRT, 83.9% in CON) did not differ between the groups. However, there was no effect of the cephapirin administration on CR on days 31 and 62 in the repeat breeder cows (43.8% in TRT and 44.0% in CON; 39.4% in TRT and 40.6% in CON, respectively). Thus, post-TAI intrauterine cephapirin administration was not found to be useful for the treatment of potential subclinical endometritis in repeat breeder dairy cows.

Özet

Subclinical endometritis contributes to repeat breeder syndrome in dairy cows. This study evaluated the effect of intrauterine cephapirin benzathine administration after timed artificial insemination (TAI) on the conception rate (CR) in repeat breeder dairy cows. To determine the antibiotic effects, all cows (n = 335) that had more than 3 services with no clinical abnormalities of the reproductive tract received the same combined synchronisation protocol: an ear implant containing progestagen using the Ovsynch protocol and a third gonadotropin-releasing hormone (GnRH) administration 7 days after TAI. Cows in the treatment group (TRT; n = 160) received intrauterine cephapirin 12 h after TAI, and cows in the control group (CON; n = 175) did not receive intrauterine antibiotics. The percentage of cows that responded to the first (67.5% in TRT, 70.9% in CON) and second (98.8% in TRT, 97.1% in CON) GnRH of Ovsynch was similar between the groups. In addition, the response to the third GnRH administration after TAI (88.1% in TRT, 83.9% in CON) did not differ between the groups. However, there was no effect of the cephapirin administration on CR on days 31 and 62 in the repeat breeder cows (43.8% in TRT and 44.0% in CON; 39.4% in TRT and 40.6% in CON, respectively). Thus, post-TAI intrauterine cephapirin administration was not found to be useful for the treatment of potential subclinical endometritis in repeat breeder dairy cows.

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Cite This Article

GÜMEN, A., MECİTOĞLU, G. Y., KESKİN, A., KARAKAYA, E., ALKAN, A., TAŞDEMİR, U., OKUT, H. (2012). The effect of intrauterine cephapirin treatment after insemination on conception rate in repeat breeder dairy cows subjected to the progesterone-based Ovsynch protocol. Turkish Journal of Veterinary and Animal Sciences, Cilt: 36 - Sayı: 6, 622–627. https://ajindex.com/articles/121680

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References (11)

  1. Veselinovic, S., Kosarcic, D., Ivkov, V., Veselinovic, S., Medic, D., Grubac, S., Popovski, K., Mickovski, G., Kosarcic, S.: Medication of chronic endometritis of cows by use of Metricure preparation. Proceedings of 2nd Symposium on Animal Reproduction, Ohrid, Macedonia. 1996.
  2. Shams-Esfandabadi, N., Shirazi, A., Ghamsemzadeh-Nava, H.: Pregnancy rate following post-insemination intrauterine treatment of endometritis in dairy cattle. J. Vet. Med., 2004; A51: 155–156.
  3. Kasimanickam, R., Duffield, T.F., Foster, R.A., Gartley, C.J., Leslie, K.E., Walton, J.S., Johnson, W.H.: Th e eff ect of a single administration of cephapirin or cloprostenol on the reproductive performance of dairy cows with subclinical endometritis. Th eriogenology, 2005; 63: 818–830.
  4. Ahmadi, M.R., Dehghan, S.A.: Evaluation of the treatment of repeat breeder dairy cows with uterine lavage plus PGF2α, with and without cephapirin. Turk J. Vet. Anim. Sci., 2007; 31: 125–129.
  5. McDougall, S.: Eff ect of periparturient disease on the reproductive performance of New Zealand dairy cows. N.Z. Vet. J., 2001; 49: 60–67.
  6. LeBlanc, S.J., Duffi eld, T.F., Leslie, K.E., Bateman, K.G., Keefe, G.P., Walton, J.S., Johnson WH.: Th e eff ect of treatment of clinical endometritis on reproductive performance in dairy cows. J. Dairy Sci. 2002; 85: 2237–2249. National Research Council: Nutrient Requirements of Dairy Cattle. 7th edn., National Academy of Sciences, Washington, DC, USA. 2001.
  7. Ferguson, J.D., Galligan, D.T., Th omsen, N.: Principal descriptors of body condition score in Holstein cows. J. Dairy Sci., 1994; 77: 2695–2703.
  8. Pursley, J.R., Mee, M.O., Wiltbank, M.C.: Synchronisation of ovulation in dairy cows using PGF2α and GnRH. Th eriogenology, 1995; 44: 915–923. Galvão, K.N., Santos, J.E.P.: Factors aff ecting synchronisation and conception rate aft er the Ovsynch protocol in lactating Holstein cows. Reprod. Domest. Anim., 2010; 45: 439–446.
  9. Stevenson, J.S., Pursley, J.R., Garverick, H.A., Fricke, P.M., Kesler, D.J., Ottobre, J.S., W iltbank, M.C.: Treatment of cycling and noncycling lactating dairy cows with progesterone during Ovsynch. J. Dairy Sci., 2006; 89: 2567–2578.
  10. Gümen, A., Guenther, J.N., Wiltbank, M.C.: Follicular size and response to Ovsynch versus detection of estrus in anovular and ovular lactating dairy cows. J. Dairy Sci., 2003; 86: 3184–3194.
  11. Bello, N.M., Steibel, J.P., Pursley, J.R.: Optimizing ovulation to fi rst GnRH improved outcomes to each hormonal injection of Ovsynch in lactating d