Journals / Turkish Journal of Veterinary and Animal Sciences / 2014 / Cilt: 38 - Sayı: 2

Treatment of canine transmissible venereal tumor using L-asparaginase, prednisone, and surgery in a clinical chemotherapy-resistant case

Pages
220–223
Publication Date
2014-05-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Complete remission was obtained with combined-modality therapy with surgery, L-asparaginase, and prednisone.

📌 3 Key Takeaways

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Objective & Hypothesis:A 4-year-old intact female dog was presented with a vaginal transmissible venereal tumor (TVT) that had clinically developed multidrug resistance to vincristine, vinblastine, and doxorubicin.
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Key Findings & Data:A 4-year-old intact female dog was presented with a vaginal transmissible venereal tumor (TVT) that had clinically developed multidrug resistance to vincristine, vinblastine, and doxorubicin.
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Conclusion & Impact:Complete remission was obtained with combined-modality therapy with surgery, L-asparaginase, and prednisone.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Key words: Cancer · Sticker tumor · transmissible venereal tumor

Abstract

A 4-year-old intact female dog was presented with a vaginal transmissible venereal tumor (TVT) that had clinically developed multidrug resistance to vincristine, vinblastine, and doxorubicin. Complete remission was obtained with combined-modality therapy with surgery, L-asparaginase, and prednisone.

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Cite This Article

SILVA, D. M. D., REUSING, M. S. D. O., FRANCIOSI, A. İ., BELO, C. E. P., GONÇALVES, K. A., SOUSA, R. S. D., GUERIOS, S. D. (2014). Treatment of canine transmissible venereal tumor using L-asparaginase, prednisone, and surgery in a clinical chemotherapy-resistant case. Turkish Journal of Veterinary and Animal Sciences, Cilt: 38 - Sayı: 2, 220–223. https://ajindex.com/articles/121624

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References (5)

  1. Thrall MA. Diagnostic cytology in clinical oncology. In: Withrow SJ, Vail DM, editors. Small Animal Clinical Oncology. 4th ed. St. Louis, MO, USA: Elsevier; 2007. pp. 112–133.
  2. Spugnini EP, Dotsinsky I, Mudrov N, Citro G, D´Avino A, Baldi A. Biphasic pulses enhance bleomycin efficacy in a spontaneous canine genital tumor model of chemoresistance: Sticker sarcoma. J Exp Clin Cancer Res 2008; 27: 58. Johnson CA. Infecções genitais e tumor venéreo transmissível. In: Nelson RW, Couto CG, editors. Fundamentos de Medicina Interna de Pequenos Animais. Rio de Janeiro, Brazil: Guanabara Koogan; 1994. pp. 522–525 (book chapter in Portuguese). Lorimier LP, Fan TM. Canine transmissible venereal tumor. In: Withrow SJ, Vail DM, editors. Small Animal Clinical Oncology. 4th ed. St. Louis, MO, USA: Elsevier; 2007. pp. 799–803.
  3. Nak D, Nak Y, Cangul IT, Tuna B. A clinico-pathological study on the effect of vincristine on transmissible venereal tumour in dogs. J Vet Med A Physiol Pathol Clin Med 2005; 52: 366–370.
  4. Sousa J, Saito V, Nardi AB, Rodaski S, Guérios SD, Bacila M. A survey on the incidence and the therapeutic procedures of the canine transmissible venereal tumor, the Sticker’s lymphosarcoma. Archives of Veterinary Science 2000; 5: 41–48 (article in Portuguese with an English abstract). Sudjaidee P, Theewasutrakul P, Techarungchaikul S, Ponglowhapan S, Chatdarong K. Treatment of canine transmissible venereal tumor using vincristine sulfate combined with L-asparaginase in clinical vincristine-resistant cases: a case report. Thai J Vet Med 2012; 42: 117–122.
  5. Said RA, Silva LF, Albuquerque AROL, Sousa-Neta EM, Lavinsky MO. Efficacy and side effects of vincristine sulfate treatment on canine transmissible venereal tumor. In: Proceedings of the 34th World Small Animal Veterinary Congress. São Paulo, Brazil: WSAVC; 2009. p. 438. Gaspar LFJ, Ferreira I, Colodel MM, Brandão CVS, Rocha NS. Spontaneous canine transmissible venereal tumor: cell morphology and influence on P-glycoprotein expression. Turk J Vet Anim Sci 2010; 34: 447–454.