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Journals / Kırıkkale Üniversitesi Tıp Fakültesi Dergisi / 2026 / Cilt: 23 Sayı: 2

Gamma Glutamyl Transpeptidase Effect in Testicular Tumor; Is a New Biomarker Born?

TESTİS TÜMÖRÜNDE GAMA GLUTAMİL TRANSPEPTİDAZ ETKİSİ; YENİ BİR BİYOBELİRTEÇ Mİ DOĞUYOR?

Batuhan Ergani(Beyhekim Eğitim ve Araştırma Hastanesi)0000-0002-4667-855X
Mehmet Yalçın(Şanlıurfa Eğitim ve Araştırma Hastanesi)0000-0001-9943-7453
Mert Hamza Özbilen(Tepecik Eğitim ve Araştırma Hastanesi, İzmir)0000-0002-5733-6790
Çağdaş Bildirici(Tepecik Eğitim ve Araştırma Hastanesi, İzmir)0000-0002-4220-8147
Erkin Karaca(Tepecik Eğitim ve Araştırma Hastanesi, İzmir)0000-0002-9123-4069
Erkan Aravacık(Tepecik Eğitim ve Araştırma Hastanesi, İzmir)0000-0002-6791-4566
Hayal Boyacıoğlu(EGE ÜNİVERSİTESİ, FEN FAKÜLTESİ, İSTATİSTİK BÖLÜMÜ)0000-0002-2990-4383
Yusuf Özlem İlbey(Tepecik Eğitim ve Araştırma Hastanesi, İzmir)0000-0002-1483-9160
Pages
309–317
Publication Date
2021-08-31
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Objective: The aim of this study is to investigate the use of serum gamma-glutamyl transpeptidase level as a biomarker especially in seminomatous subtype disease in testicular tumor patients and to investigate the superiority of biomarkers currently in use, and to examine the role of serum gamma-glutamyl transpeptidase levels in chemotherapy response, maintenance and nephrotoxicity in patients receiving cisplatin-based chemotherapy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: The aim of this study is to investigate the use of serum gamma-glutamyl transpeptidase level as a biomarker especially in seminomatous subtype disease in testicular tumor patients and to investigate the superiority of biomarkers currently in use, and to examine the role of serum gamma-glutamyl transpeptidase levels in chemotherapy response, maintenance and nephrotoxicity in patients receiving cisplatin-based chemotherapy.
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Key Findings & Data:Objective: The aim of this study is to investigate the use of serum gamma-glutamyl transpeptidase level as a biomarker especially in seminomatous subtype disease in testicular tumor patients and to investigate the superiority of biomarkers currently in use, and to examine the role of serum gamma-glutamyl transpeptidase levels in chemotherapy response, maintenance and nephrotoxicity in patients receiving cisplatin-based chemotherapy.
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Conclusion & Impact:Objective: The aim of this study is to investigate the use of serum gamma-glutamyl transpeptidase level as a biomarker especially in seminomatous subtype disease in testicular tumor patients and to investigate the superiority of biomarkers currently in use, and to examine the role of serum gamma-glutamyl transpeptidase levels in chemotherapy response, maintenance and nephrotoxicity in patients receiving cisplatin-based chemotherapy.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Biyobelirteç · Gama-glutamil transpeptidaz · Testis tümörü.

Abstract

Objective: The aim of this study is to investigate the use of serum gamma-glutamyl transpeptidase level as a biomarker especially in seminomatous subtype disease in testicular tumor patients and to investigate the superiority of biomarkers currently in use, and to examine the role of serum gamma-glutamyl transpeptidase levels in chemotherapy response, maintenance and nephrotoxicity in patients receiving cisplatin-based chemotherapy.

Özet

Amaç: Bu çalışmanın amacı testis tümörü hastalarında serum gama-glutamil transpeptidaz düzeyinin özellikle seminomatöz alt tipteki hastalıkta bir biyobelirteç olarak kullanılabilirliğinin, mevcut kullanımda olan biyobelirteçlere üstünlüğünün araştırılması ile sisplatin temelli kemoterapi alan hastalarda serum gama-glutamil transpeptidaz seviyelerinin kemoterapi yanıtı, devamı ve nefrotoksisitedeki rollerini incelemektir.

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Cite This Article

Ergani, B., Yalçın, M., Özbilen, M. H., Bildirici, Ç., Karaca, E., Aravacık, E., Boyacıoğlu, H., İlbey, Y. Ö. (2021). Gamma Glutamyl Transpeptidase Effect in Testicular Tumor; Is a New Biomarker Born?. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi, Cilt: 23 Sayı: 2, 309–317. https://doi.org/10.24938/kutfd.900045

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