Journals / Kırıkkale Üniversitesi Tıp Fakültesi Dergisi / 2026 / Cilt: 28 Sayı: 2

PREDICTIVE PARAMETERS IN DECISION-MAKING FOR SURGICAL INTERVENTION AND PATIENTS' PROGNOSIS IN ISOLATED INTRACRANIAL EPIDURAL HEMATOMA

İzole İntrakraniyal Epidural Hematomda Cerrahi Müdahaleye Karar Vermede ve Hastanın Prognozunda Prediktif Parametreler

Alemiddin Özdemir(Kirikkale University Faculty of Medicine, Department of Neurosurgery)0000-0002-5431-7287
Ahmet Melih Erdoğan(Kirikkale University Faculty of Medicine, Department of Neurosurgery)0000-0002-9924-9476
Cansel Çetin(Clinic of Emergency Medicine, Ankara Bilkent City Hospital, Ministry of Health of Türkiye, ANKARA, TÜRKİYE)0000-0003-0921-7786
Nazlı Görmeli Kurt(Clinic of Emergency Medicine, Ankara Bilkent City Hospital, Ministry of Health of Türkiye, ANKARA, TÜRKİYE)0000-0003-1757-9488
Özge Aydın(Kirikkale University Faculty of Medicine, Department of Neurosurgery)0009-0004-6265-2351
Mustafa Öğden(Kirikkale University Faculty of Medicine, Department of Neurosurgery)0000-0002-7129-0936
Ulaş Yüksel(Kirikkale University Faculty of Medicine, Department of Neurosurgery)0000-0002-6398-4110
Bülent Bakar(Kirikkale University Faculty of Medicine, Department of Neurosurgery)0000-0002-6236-7647
Pages
263–277
Publication Date
2026-08-12
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: The study results suggested that hematoma thickness, midline shift values, and some blood biochemistry parameters could be used as predictive markers in the decision-making for surgical intervention in patients with isolated EDH.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: This study aimed to predict surgical intervention decision and early prognosis in patients with isolated intracranial epidural hematoma (EDH) using clinical, laboratory, and radiological parameters obtained at admission to the hospital.
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Key Findings & Data:Materials and Methods: Eighty-three patients with EDH due to "fall from a height" or "traffic accident" were examined.
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Conclusion & Impact:Conclusion: The study results suggested that hematoma thickness, midline shift values, and some blood biochemistry parameters could be used as predictive markers in the decision-making for surgical intervention in patients with isolated EDH.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Epidural hematom · cerrahi · prognoz.

Abstract

Objective: This study aimed to predict surgical intervention decision and early prognosis in patients with isolated intracranial epidural hematoma (EDH) using clinical, laboratory, and radiological parameters obtained at admission to the hospital. Materials and Methods: Eighty-three patients with EDH due to "fall from a height" or "traffic accident" were examined. For each patient, age, gender, Glasgow Coma Scale (GCS) scores on admission to the hospital, anisocoria, duration of stay in the intensive care unit and the hospital, and Glasgow Outcome Scale scores were recorded. Brain CT images obtained on admission to the hospital were examined, and the hematoma thickness and midline shift values were measured. Additionally, patients' blood biochemistry results were recorded. Results: ROC curve analysis revealed that hematoma thickness, midline shift, basophil count, and serum potassium level were predictive parameters for surgical intervention in pediatric patients. In addition, preoperative hematoma thickness and midline shift, serum sodium, potassium, ALT, and CRP values could predict the decision to perform surgical intervention in adult patients. Finally, GCS scores and serum sodium values could predict patients' early outcomes. Conclusion: The study results suggested that hematoma thickness, midline shift values, and some blood biochemistry parameters could be used as predictive markers in the decision-making for surgical intervention in patients with isolated EDH. Additionally, the GCS score determined at admission to the hospital could be used as a predictive marker of patients’ early prognosis.

Özet

Amaç: Bu çalışma, izole intrakraniyal epidural hematom (EDH) tanısı alan hastaların hastaneye kabulünden elde edilen klinik, laboratuvar ve radyolojik parametreleri kullanarak cerrahi müdahale kararı verme ve prognozunu öngörmeyi amaçladı. Gereç ve Yöntem: "Yüksekten düşme" veya "trafik kazası" nedeniyle EDH gelişen 83 hastanın verileri incelendi. Her hastanın yaşı, cinsiyeti, hastaneye başvuru anındaki Glasgow Koma Skalası (GCS) skorları, anizokori, yoğun bakım ve hastanede kalış süreleri ve Glasgow Sonuç Skalası skorları kaydedildi. Hastaneye başvuruda elde edilen beyin BT görüntüleri incelenerek hematom kalınlığı ve orta hat kayması değerleri ölçüldü. Ayrıca hastaların hastaneye başvuru anından itibaren elde edilen kan biyokimyası sonuçları da kaydedildi. Bulgular: ROC eğrisi analizi, preoperatif hematom kalınlığı ve orta hat kayması değerleri, bazofil sayısı ve serum potasyum düzeyi değerlerinin pediatrik hastalarda cerrahi müdahale kararının verilmesinde belirleyici parametreler olabileceğini ortaya koydu. Ayrıca ameliyat öncesi hematom kalınlığı ve orta hat kayması değerleri, serum sodyum, potasyum, ALT ve CRP değerleri erişkin hastalarda cerrahi müdahale kararını öngörebilecek parametreler olabileceği saptandı. Son olarak, regresyon analizi GCS skorlarının ve serum sodyum değerlerinin hastaların erken prognozunu öngörebileceğini ortaya koydu. Sonuç: Çalışma sonuçları, izole EDH'li hastalarda cerrahi müdahaleye karar vermede hematom kalınlığı, orta hat kayması değerleri ve bazı kan biyokimyası parametrelerinin öngörücü belirteçler olarak kullanılabileceğini düşündürdü. Ayrıca hastaneye başvuru sırasında belirlenen GCS skorunun hastaların erken dönem prognozunu öngörmede bir belirteç olarak kullanılabileceği savunuldu.

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Cite This Article

Özdemir, A., Erdoğan, A. M., Çetin, C., Kurt, N. G., Aydın, Ö., Öğden, M., Yüksel, U., Bakar, B. (2026). PREDICTIVE PARAMETERS IN DECISION-MAKING FOR SURGICAL INTERVENTION AND PATIENTS' PROGNOSIS IN ISOLATED INTRACRANIAL EPIDURAL HEMATOMA. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi, Cilt: 28 Sayı: 2, 263–277. https://doi.org/10.24938/kutfd.1893145

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References (23)

  1. Moon RD, Abdulla MA, Kolias AG, et al. The impact of major trauma centre implementation on the pathways and outcome of traumatic intracranial extradural haematoma in a regional centre. Br J Neurosurg. 2016;30(5):541-544.
  2. Jeong YH, Oh JW, Cho S; Korean Trauma Data Bank System Committee. Clinical Outcome of Acute Epidural Hematoma in Korea: Preliminary Report of 285 Cases Registered in the Korean Trauma Data Bank System. Korean J Neurotrauma. 2016;12(2):47-54.
  3. Lee EJ, Hung YC, Wang LC, Chung KC, Chen HH. Factors influencing the functional outcome of patients with acute epidural hematomas: analysis of 200 patients undergoing surgery. J Trauma. 1998;45(5):946-952.
  4. Lobato RD, Rivas JJ, Cordobes F, et al. Acute epidural hematoma: an analysis of factors influencing the outcome of patients undergoing surgery in coma. J Neurosurg. 1988;68(1):48-57.
  5. Rosyidi RM, Priyanto B, Al Fauzi A, Sutiono AB. Toward zero mortality in acute epidural hematoma: a review of 268 cases problems, and challenges in the developing country. Interdiscip Neurosurg. 2019; 17:12-18.
  6. Balmer B, Boltshauser E, Altermatt S, Gobet R. Conservative management of significant epidural haematomas in children. Child's Nerv Syst. 2006;22(4):363-367.
  7. Marmarou A, Lu J, Butcher I, et al. Prognostic value of the Glasgow Coma Scale and pupil reactivity in traumatic brain injury assessed pre-hospital and on enrollment: an IMPACT analysis. J Neurotrauma. 2007;24(2):270-280.
  8. Paci GM, Sise MJ, Sise CB, et al. Preemptive craniectomy with craniotomy: what role in the management of severe traumatic brain injury? J Trauma. 2009;67(3):531-536.
  9. Bullock MR, Chesnut R, Ghajar J, et al Surgical management of acute epidural hematomas. Neurosurgery. 2006;58(3 Suppl):S7-15.
  10. Gutowski P, Meier U, Rohde V, Lemcke J, von der Brelie C. Clinical Outcome of Epidural Hematoma Treated Surgically in the Era of Modern Resuscitation and Trauma Care. World Neurosurg. 2018;118:e166-e174.
  11. Flaherty BF, Moore HE, Riva-Cambrin J, Bratton SL. Pediatric patients with traumatic epidural hematoma are at low risk for deterioration and need for surgical treatment. J Pediatr Surg. 2017;52(2):334-339.
  12. Call L, Qiu Q, Morris J, et al. Characteristics of pediatric patients with traumatic epidural hematomas who can be safely observed: a clinical validation study. Br J Radiol. 2020;93(1114):20190968.
  13. Choi DH, Jeong TS, Kim WK; KNTDB Investigators. Clinical Outcome of Patients Diagnosed with Traumatic Intracranial Epidural Hematoma with Severe Brain Injury (Glasgow Coma Scale ≤8) Who Undergo Surgery: A Report from the Korean Neuro-Trauma Data Bank System. Korean J Neurotrauma. 2022;18(2):153-160.
  14. Teasdale G, Jennett B. Assessment of coma and impaired consciousness. A practical scale. Lancet. 1974;2(7872):81-84.
  15. Jennett B, Bond M. Assessment of outcome after severe brain damage. Lancet. 1975;1(7905):480-484.
  16. Kang J, Hong S, Hu C, et al. Clinical Analysis of Delayed Surgical Epidural Hematoma. Korean J Neurotrauma. 2015;11(2):112-117.
  17. Xiao B, Ma MY, Duan ZX, Liu JG, Chen RP, Mao Q. Could a traumatic epidural hematoma on early computed tomography tell us about its future development? A multi-center retrospective study in China. J Neurotrauma. 2015;32(7):487-494.
  18. Srinivasaiah B, Venkataramaiah S, Sadashiva N, Kamath S, Shukla D. Impact of perioperative factors on short-term outcomes after emergency surgery for acute traumatic extradural hematoma - A retrospective cohort study. Clin Neurol Neurosurg. 2023; 232: 107874.
  19. Echara M, Das AK, Agrawal M, Gupta A, Sharma A, Singh SK. Prognostic Factors and Outcome of Surgically Treated Supratentorial versus Infratentorial Epidural Hematoma in Pediatrics: A Comparative Study of 350 Patients at a Tertiary Center of a Developing Country. World Neurosurg. 2023;171: e447-e455.
  20. Pang D, Horton JA, Herron JM, Wilberger JE Jr, Vries JK. Nonsurgical management of extradural hematomas in children. J Neurosurg. 1983;59(6):958-971.
  21. Knuckey NW, Gelbard S, Epstein MH. The management of "asymptomatic" epidural hematomas. A prospective study. J Neurosurg. 1989;70(3):392-396.
  22. Khalid S, Khan SA, Abbasi T, Aurangzeb A, Faiza, Khan AM. Mortality and Prognostic Factors In Patients Operated on for Acute Epidural Hematoma. J Ayub Med Coll Abbottabad. 2023;35(Suppl 1):S769-S773.
  23. Kim NY, Lim J, Lee S, Kim K, Hong JH, Chun DH. Hematological factors predicting mortality in patients with traumatic epidural or subdural hematoma undergoing emergency surgical evacuation: A retrospective cohort study. Medicine (Baltimore). 2020;99(37):e22074.