Concentrations of manganese, iron, and strontium in bones of thedomestic dog (Canis lupus familiaris)

Objective & Hypothesis:The aim of this study was to determine concentrations of manganese (Mn), iron (Fe), and strontium (Sr) in the cartilage, compact bone, spongy bone, and cartilage with adjacent compact bone of the domestic dog (Canis lupus familiaris).

📊

Key Findings & Data:The experiment was carried out on bones from the hip joints of 24 dogs (dogs of 8 years) from northwestern Poland.

💡

Conclusion & Impact:Keywords: Iron, manganese, strontium, dog, Poland Full Text: PDF

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Iron · manganese · strontium

Abstract

The aim of this study was to determine concentrations of manganese (Mn), iron (Fe), and strontium (Sr) in the cartilage, compact bone, spongy bone, and cartilage with adjacent compact bone of the domestic dog (Canis lupus familiaris). The experiment was carried out on bones from the hip joints of 24 dogs (dogs of 8 years) from northwestern Poland. The concentrations of Mn, Fe, and Sr were assessed by atomic absorption spectrophotometry. Fe concentration was the highest in the cartilage and compact bone. Mn concentration was the lowest in all three types of bone material and had a significantly lower concentration in spongy bone than in the other bone materials. Sr concentration was the highest in the spongy bone. Age-dependent comparison showed that both Mn and Fe concentration in dogs of 0.70) were found between Mn and Fe and between Mn and Sr concentrations in cartilage, and between Sr concentrations in compact bone and cartilage with adjacent compact bone. In most of the studied dogs, bone Mn, Fe, and Sr concentrations were similar to those found in other canines and different from ungulates and micromammals. Keywords: Iron, manganese, strontium, dog, Poland Full Text: PDF

Özet

The aim of this study was to determine concentrations of manganese (Mn), iron (Fe), and strontium (Sr) in the cartilage, compact bone, spongy bone, and cartilage with adjacent compact bone of the domestic dog (Canis lupus familiaris). The experiment was carried out on bones from the hip joints of 24 dogs (dogs of 8 years) from northwestern Poland. The concentrations of Mn, Fe, and Sr were assessed by atomic absorption spectrophotometry. Fe concentration was the highest in the cartilage and compact bone. Mn concentration was the lowest in all three types of bone material and had a significantly lower concentration in spongy bone than in the other bone materials. Sr concentration was the highest in the spongy bone. Age-dependent comparison showed that both Mn and Fe concentration in dogs of 0.70) were found between Mn and Fe and between Mn and Sr concentrations in cartilage, and between Sr concentrations in compact bone and cartilage with adjacent compact bone. In most of the studied dogs, bone Mn, Fe, and Sr concentrations were similar to those found in other canines and different from ungulates and micromammals. Keywords: Iron, manganese, strontium, dog, Poland Full Text: PDF

Keywords

Iron manganese strontium dog Poland

🔖

Cite This Article

BUDIS, H., KALISINSKA, E., LANOCHA, N., KOSIK_BOGACKA, D. (2015). Concentrations of manganese, iron, and strontium in bones of thedomestic dog (Canis lupus familiaris). Turkish Journal of Veterinary and Animal Sciences, Cilt: 39 - Sayı: 3, 279–286. https://ajindex.com/articles/121440

📄 Full Text PDF Viewer

Open in New Tab ↗

↗New Tab

📄

PDF görüntüleyici hazırlanıyor...

References (10)

Gehrke M. Copper and manganese in the pathogenesis of diseases of the skeletal system of animals. Med Wet 1997; 53: 644–646. 7. Agency for Toxic Substances and Disease Registry. Toxicological Profile for Manganese. Washington, DC, USA: United States Department of Health and Human Services; 2008. 8. Sanchez D, Domingo JL, Llobet JM, Keen CL. Maternal and developmental toxicity of manganese in the mouse. Toxicol Lett 1993; 69: 45–52. 9. Doyle D, Kapron CM. Inhibition of cell differentiation by manganese chloride in micromass cultures of mouse embryonic limb bud cells. Toxicol In Vitro 2002; 16: 101–106.
Shorr E, Carter AC. The usefulness of strontium as an adjuvant to calcium in the remineralization of skeleton in man. Bull Hosp Joint Dis 1952; 13: 59–66.
Delanoy P, Bazot D, Marie PJ. Long-term treatment with strontium ranelate increases vertebral bone mass without deleterious effect in mice. Metabolism 2002; 51: 906–911.
Choundary S, Halbout P, Alander C, Raisz L, Pilbeam C. Strontium ranelate promotes osteoblastic differentiation and mineralization of murine bone marrow stromal cells: involvement of prostaglandins. J Bone Miner Res 2007; 22: 1002–1010. World Health Organization. Strontium and strontium compounds. Concr Int Chem Assess Doc 2010; 77: 1–67.
Johnson AR, Armstrong WD, Singer L. The incorporation and removal of large amounts of strontium by physiologic mechanisms in mineralized tissues. Calcif Tissue Res 1968; 2: 242–252.
Lindblad-Toh K, Wade CM, Mikkelsen TS, Karlsson EK, Jaffe DB, Kamal M, Clamp M, Chang JL, Kulbokas EJ 3rd, Zody MC et al. Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature 2005; 438: 803–819.
Egermann M, Goldhahn J, Schneider E. Animal models for fracture treatment in osteoporosis. Osteoporos Int 2005; 16: 129–138.
Scurula CP, Pluhar GE, Frankel DJ, Egger EL, James SP. Assessing the dog as a model for human total hip replacement. Analysis of 38 canine cemented components retrieved at post- mortem. J Bone Joint Surg Br 2005; 87: 120–127.
Lanocha N, Kalisinska E, Kosik-Bogacka D, Budis H. Evaluation of dog bones in the indirect assessment of environmental contamination with trace elements. Biol Trace Elem Res 2012; 147:103–112.
Millan J, Mateo R, Taggart MA, Lopez-Bao JV, Viota M, Monsalve L, Camarero PR, Blazquez E, Jimenez B. Levels of heavy metals and metalloids in critically endangered Iberian lynx and other wild carnivores from Southern Spain. Sci Total Environ 2008; 399: 193–201. Howe