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Journals / Turkish Journal of Veterinary and Animal Sciences / 2015 / Cilt: 39 - Sayı: 3

Estimating allele frequencies of some hereditary diseases in Holstein cattlereared in Burdur Province, Turkey

Özgecan Korkmaz AĞAOĞLU
Ali Reha AĞAOĞLU
Mustafa SAATCI
Pages
338
Publication Date
2015-08-13
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The results showed that the percentages of carrier animals for BLAD and FXID were 2% and 1.8%, respectively, while no DUMPS or BC was found in the study population.

📌 3 Key Takeaways

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Objective & Hypothesis:The economics of dairy cattle breeding around the world has been significantly affected by the autosomal recessive hereditary diseases of bovine leukocyte adhesion deficiency (BLAD), factor XI deficiency (FXID), bovine citrullinemia (BC), and deficiency of uridine monophosphate synthase (DUMPS).
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Key Findings & Data:This study involved taking blood samples randomly from 500 head of Holstein cattle at various dairy farms in different towns in Burdur Province.
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Conclusion & Impact:The results showed that the percentages of carrier animals for BLAD and FXID were 2% and 1.8%, respectively, while no DUMPS or BC was found in the study population.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Cattle · BLAD · FXID

Abstract

The economics of dairy cattle breeding around the world has been significantly affected by the autosomal recessive hereditary diseases of bovine leukocyte adhesion deficiency (BLAD), factor XI deficiency (FXID), bovine citrullinemia (BC), and deficiency of uridine monophosphate synthase (DUMPS). The aim of this study was to determine BLAD, FXID, BC, and DUMPS alleles in Holstein cattle raised in Burdur Province in Turkey. This study involved taking blood samples randomly from 500 head of Holstein cattle at various dairy farms in different towns in Burdur Province. Polymerase chain reaction and restriction fragment length polymorphism (PCR-RFLP) analysis was employed to identify cows with these diseases. The results showed that the percentages of carrier animals for BLAD and FXID were 2% and 1.8%, respectively, while no DUMPS or BC was found in the study population. This is the first study on BLAD, FXID, BC, and DUMPS in Holstein cattle raised in Burdur Province in Turkey.

Özet

The economics of dairy cattle breeding around the world has been significantly affected by the autosomal recessive hereditary diseases of bovine leukocyte adhesion deficiency (BLAD), factor XI deficiency (FXID), bovine citrullinemia (BC), and deficiency of uridine monophosphate synthase (DUMPS). The aim of this study was to determine BLAD, FXID, BC, and DUMPS alleles in Holstein cattle raised in Burdur Province in Turkey. This study involved taking blood samples randomly from 500 head of Holstein cattle at various dairy farms in different towns in Burdur Province. Polymerase chain reaction and restriction fragment length polymorphism (PCR-RFLP) analysis was employed to identify cows with these diseases. The results showed that the percentages of carrier animals for BLAD and FXID were 2% and 1.8%, respectively, while no DUMPS or BC was found in the study population. This is the first study on BLAD, FXID, BC, and DUMPS in Holstein cattle raised in Burdur Province in Turkey.

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Cite This Article

AĞAOĞLU, Ö. K., AĞAOĞLU, A. R., SAATCI, M. (2015). Estimating allele frequencies of some hereditary diseases in Holstein cattlereared in Burdur Province, Turkey. Turkish Journal of Veterinary and Animal Sciences, Cilt: 39 - Sayı: 3, 338. https://ajindex.com/articles/121439

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References (12)

  1. Marron BM, Robinson JL, Gentry PA, Beever JE. Identification of a mutation associated with factor XI deficiency in Holstein cattle. Anim Genet 2004; 35: 454–456.
  2. Meydan H, Yıldız MA, Agerholm JS. Screening for bovine leukocyte adhesion deficiency, deficiency of uridine monophosphate synthase, complex vertebral malformation, bovine citrullinaemia, and factor XI deficiency in Holstein cows reared in Turkey. Acta Vet Scand 2010; 52: 56. Citek J, Rehout V, Hajkova J Pavkova J. Monitoring of the genetic health of cattle in the Czech Republic. Vet Med 2006; 51: 333–339.
  3. Shuster DE, Kehrli ME, Ackerman MR, Gilbert RO. Identification and prevalence of a genetic defect that causes leukocyte adhesion deficiency in Holstein cattle. Proceedings of the National Academy of Sciences 1992; 89: 9225–9229. Nagahata H. Bovine leukocyte adhesion deficiency (BLAD): a review. J Vet Med Sci 2004; 66: 1475–1482.
  4. Akyuz B, Ertugrul O. Detection of bovine leukocyte adhesion deficiency (BLAD) in Turkish native and Holstein cattle. Acta Vet Hung 2006; 54: 173–178.
  5. Li J, Wang H, Zhang Y, Hou M, Zhong J, Zhang Y. Identification of BLAD and citrullinemia carriers in Chinese Holstein cattle. Anim Sci Pap Rep 2011; 29: 37–42.
  6. Jorgensen CB, Agerholm JS, Pedersen J, Thomsen PD. Bovine leukocyte adhesion deficiency in Danish Holstein-Friesian cattle. I. PCR screening and allele frequency estimation. Acta Vet Scand 1993; 34: 231–236.
  7. Nagahata H, Nochi H, Tamto K, Tani Yama H, Noda H, Morita M, Kanamaki M, Kociba GJ. Bovine leukocyte adhesion deficiency in Holstein cattle. Can J Vet Res 1993; 55: 40–48.
  8. Öner Y, Keskin A, Elmaci C. Identification of BLAD, DUMPS, citrullinaemia and factor XI deficiency in Holstein cattle in Turkey. Asian J Anim Vet Adv 2010; 5: 60–65.
  9. Sahin E, Karslı T, Galiç A, Balcıoğlu MS. Identification of bovine leukocyte adhesion deficiency (BLAD) and bovine citrullinaemia (BC) alleles in Holstein cows reared in Antalya region. J App Anim Res 2013; 41: 56–60.
  10. Lee YK, Chang KW, Nam IS, Chang WK, Tak TY, Kim KN, Lee KJ. Studies on the detection of congenital genetic disorder in Holstein proven and candidate bulls. J Anim Sci Tech 2002; 44: 279–288.
  11. Citek J, Blahova B. Recessive disorders—a serious health hazard? J Appl Biomed 2004; 2: 187–194. Kamiñski S, Grzybowski G, Prusak B, Rusc A. No incidence of DUMPS carriers in Polish dairy cattle. J Appl Genet 2005; 46: 395–397.
  12. Kociba GD, Ratnoff OD, Loeb WF, Wall RL, Heider LE. Bovine thromboplastin antecedent (factor XI) deficien