The spectroscopic and structural properties of two different types of radicals induced by radiation were determined by spectrum simulation.
📌 3 Key Takeaways
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Objective & Hypothesis:In this study, the suitability of usage as a dosimetric material of Chlorpromazine, which is used in treatment of neurological diseases, was determined and also its signal fading, microwave saturation behaviour and dose-response curve information were investigated at room temperature. Chlorpromazine sample was irradiated by γ-rays at significiant doses and Electron Spin Resonance (ESR) spectra were recorded. ESR signal was not detected in unirradiated samples.
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Key Findings & Data:In this study, the suitability of usage as a dosimetric material of Chlorpromazine, which is used in treatment of neurological diseases, was determined and also its signal fading, microwave saturation behaviour and dose-response curve information were investigated at room temperature. Chlorpromazine sample was irradiated by γ-rays at significiant doses and Electron Spin Resonance (ESR) spectra were recorded. ESR signal was not detected in unirradiated samples.
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Conclusion & Impact:The spectroscopic and structural properties of two different types of radicals induced by radiation were determined by spectrum simulation.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:ESR · Dozimetri · Gama radyasyonu
Abstract
In this study, the suitability of usage as a dosimetric material of Chlorpromazine, which is used in treatment of neurological diseases, was determined and also its signal fading, microwave saturation behaviour and dose-response curve information were investigated at room temperature. Chlorpromazine sample was irradiated by γ-rays at significiant doses and Electron Spin Resonance (ESR) spectra were recorded. ESR signal was not detected in unirradiated samples. The spectroscopic and structural properties of two different types of radicals induced by radiation were determined by spectrum simulation.
Özet
Bu çalışmada, nörolojik hastalıkların tedavisinde kullanılan ilaç etkin madde Klorpromazin örneğinin dozimetrik malzeme olarak kullanıma uygunluğu, radikal sönüm bilgileri, mikrodalga güç değerlerinde doyum bilgileri ve doz-cevap eğrisi oda sıcaklığında araştırılmıştır. Klorpromazin örneği belli doz değerlerinde γ-ışınları ile ışınlanmış ve Elektron Spin Rezonans (ESR) spektrumları kaydedilmiştir. Işınlanmamış örneklerde ESR sinyali gözlenmemiştir. Spektrum simülasyonu (benzetişimi) yapılarak radyasyon sonucunda oluşan iki farklı türdeki radikalin spektroskopik ve yapısal özellikleri belirlenmiştir.
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